Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robert D. Klein"'
Autor:
Thomas M. Fandel, Tom F. Lue, Kavirach Tantiwongse, Anthony J Bella, William O. Brant, Robert D Klein, Carlos A Garcia
Publikováno v:
Journal of Brachial Plexus and Peripheral Nerve Injury
Journal of Brachial Plexus and Peripheral Nerve Injury, Vol 2, Iss 1, p 5 (2007)
Journal of Brachial Plexus and Peripheral Nerve Injury, Vol 2, Iss 1, p 5 (2007)
Background The molecular mechanisms responsible for the survival and preservation of function for adult parasympathetic ganglion neurons following injury remain incompletely understood. However, advances in the neurobiology of growth factors, neural
Autor:
Christopher E. Henderson, Daniel Eric Sherman, Frederic J. de Sauvage, Alain Garces, Richard Vejsada, Robert D. Klein, Malú G. Tansey, Kelli S. Simburger, Kristian Todd Poulsen, Patricia A. Lampe, Robert O. Heuckeroth, Christa L. Gray, Eugene M. Johnson, Paul T. Kotzbauer, Judith P. Golden, Ann C. Kato, Li-Chong Wang, Melanie L. Leitner, Jeffrey Milbrandt, Merry Nishimura, Barbara Moffat, Heidi S. Phillips, Richard Vandlen, Robert H. Baloh, Timothy J. Fahrner, Jamie A. Davies, Mary Hynes
Publikováno v:
Neuron. 20(2):245-253
A novel neurotrophic factor named Persephin that is approximately 40% identical to glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) has been identified using degenerate PCR. Persephin, like GDNF and NTN, promotes the survival of
Autor:
Robert D. Klein, Arnon Rosenthal, Heidi S. Phillips, Mark Armanini, Mary Hynes, Kristian Todd Poulsen
Publikováno v:
Neuron. 13:1245-1252
The vertebrate ventral midbrain contains 3-4 x 10(4) dopaminergic neurons that influence motor activity, emotional behavior, and cognition. Recently, glial cell line-derived neurotrophic factor (GDNF) was shown to be a potent survival factor for thes
Autor:
Barbara J Meyer, Robert D. Klein
Publikováno v:
Cell. 72:349-364
sdc-3 is an early-acting regulatory gene that controls both sex determination and X chromosome dosage compensation in C. elegans. It is unique among sdc genes in that its sex determination and dosage compensation functions act independently. The mole
Autor:
Bruce F. O'Hara, Paul Franken, Robert D. Klein, Winston Thomas, Thadd Reeder, Theodore C. Dumas, Xinmin Xie, Judith Flores, Lamont Tang, Thomas J. Brennan, H. Craig Heller
Publikováno v:
Brain research. 1052(2)
The Na(+)-independent alanine-serine-cysteine transporter 1 (Asc-1) is exclusively expressed in neuronal structures throughout the central nervous system (CNS). Asc-1 transports small neutral amino acids with high affinity especially for D-serine and
Autor:
Masahide Takahashi, Yosuke Iwata, Keizo Horibe, Chika Nozaki, Robert D. Klein, Hideki Murakami, Toshihide Iwashita, Arnon Rosenthal, Naoya Asai
Publikováno v:
Oncogene. 16(3)
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) define a new family of neurotrophic factors that play crucial roles in survival and differentiation of various neurons. Recent studies demonstrated that GDNF and NTN use a multico
Autor:
Audrey Goddard, Gregory L. Bennett, Daniel Eric Sherman, Barbara Moffat, Mark Armanini, Qimin Gu, Kristian Todd Poulsen, Robert D. Klein, Chris E. Henderson, Wei-Hsien Ho, Arnon Rosenthal, Chika Nozaki, Naoya Asai, Heidi S. Phillips, Richard Vandlen, Masahide Takahashi, Donna M. Stone, Brigitte Devaux, Laura C. Simmons, Jo-Anne Hongo
Publikováno v:
Nature. 387(6634)
Glial-cell-line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent survival factors for sympathetic, sensory and central nervous system neurons. GDNF mediates its actions through a multicomponent receptor syst
Autor:
Robert D. Klein, Hansjorg Sauer, Heidi S. Phillips, Mark Armanini, Isabel Fariñas, Mark W. Moore, Anne M. Ryan, Karen Carver-Moore, Arnon Rosenthal, Louis F. Reichardt
Publikováno v:
Nature. 382(6586)
GLIAL cell-line derived neurotrophic factor (GDNF) is a potent survival factor for embryonic midbrain dopaminergic1, spinal motor2, cranial sensory3, sympathetic, and hindbrain noradrenergic4 neurons, and is available to these cells in vivo. It is th
Autor:
Christopher E. Henderson, Audrey Goddard, A. Takahashi, Wei-Hsien Ho, Kristian Todd Poulsen, Gregory L. Bennett, Mark Armanini, Heidi S. Phillips, Richard Vandlen, J. A. Hongo, Brigitte Devaux, Qimin Gu, Chika Nozaki, Laura C. Simmons, Donna M. Stone, Daniel Eric Sherman, Robert D. Klein, Arnon Rosenthal, Naoya Asai, Barbara Moffat
Publikováno v:
Nature. 392:210-210
Autor:
Craig A. Hauser, Tammy K. Learned, Alexandra L. Joyner, Robert D. Klein, Gail R. Martin, Robert Tjian
Publikováno v:
Cell. 43(1)
Human chromosome 17 contains a cluster of at least three distinct homeo box regions, Hu1, Hu2, and Hu5, within a 20 kb stretch of DNA. A mouse homeo box region, Mu1, which maps to chromosome 11, was isolated and found to contain extensive nucleotide