Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert D. Jordan"'
Autor:
Sammy G. Duncan, Robert D. Jordan, Jenny L. Wiley, John W. Huffman, Julia A.H. Lainton, Dong Dai, David R. Compton, Billy R. Martin, W. Kenneth Banner, Shu Yu
Publikováno v:
Tetrahedron. 53:1557-1576
The synthesis of both side chain epimers of 1′-( 4 ), 2′-( 5 ), 3′-methyl-( 6 ) and 4′-methyl-Δ 8 -tetrahydrocannabinol ( 7 ) has been carried out. The synthetic approach entailed the acid catalyzed condensation of the appropriate substitute
Publikováno v:
ChemInform. 22
Autor:
John W. Huffman, S. G. Jun. Duncan, Jenny L. Wiley, Julia A.H. Lainton, Robert D. Jordan, Shu Yu, W. K. Banner, Dong Dai, David R. Compton, Billy R. Martin
Publikováno v:
ChemInform. 28
Publikováno v:
The Journal of Organic Chemistry. 56:2081-2086
Both enantiomers of the synthetic cannabinoid nabilone (4) have been synthesized from a common intermediate, enone 7. Enone 7 was prepared by reaction of [2,6-dimethoxy-4-(1,1-dimethylheptyl) phenyl] lithium with (+)-apoverbenone (2), followed by PDC
Publikováno v:
Life sciences. 56(23-24)
The synthesis of (2'RS)-2'-methyl-, (3'RS)-, (3'S)-3'-methyl-, and 4'-methyl-delta 8-THC has been carried out, and the pharmacology of all four compounds has been investigated. All four compounds showed typical cannabinoid activity both in vitro and