Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Robert D. Guber"'
Publikováno v:
Annals of Global Health, Vol 88, Iss 1 (2022)
Coronavirus disease 2019 (COVID-19) has placed an unprecedented strain on healthcare systems worldwide, but while high-income countries (HICs) have been able to adapt, low- and middle-income countries (LMICs) have been much slower to do so due to a l
Externí odkaz:
https://doaj.org/article/43fa2f98f1694793a3cbfe6f750c00e2
Publikováno v:
Thrombosis Research. 208:52-57
The Caprini risk assessment model is widely used for venous thromboembolism (VTE) but has limited data in trauma. The study objective was to determine if the Caprini risk assessment model could effectively risk stratify trauma patients.We performed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbaa8fbe027353550b2d419854a6c15
https://doi.org/10.1016/j.thromres.2021.10.016
https://doi.org/10.1016/j.thromres.2021.10.016
Autor:
Robert D. Guber, Karim Alavi, Jennifer S. Davids, Jeremy E. Springer, Paul R. Sturrock, Justin A. Maykel
Publikováno v:
Diseases of the colon and rectum. 64(10)
INTRODUCTION Completion proctectomy is traditionally performed using a combination of abdominal and perineal approaches. Access to and exposure of the pelvis through the abdominal cavity can be limited in patients with prior surgery or inflammatory c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a71f525f5f3b05b0057a627694a818e
https://pubmed.ncbi.nlm.nih.gov/34285146
https://pubmed.ncbi.nlm.nih.gov/34285146
Autor:
Maher S. Budron, Christopher Grunseich, Robert D. Guber, Alice B. Schindler, Yuebing Li, Ke-lian Chen, Kenneth H. Fischbeck
Publikováno v:
Annals of Clinical and Translational Neurology
Amyotrophic lateral sclerosis 8 (ALS8) is a rare progressive neurodegenerative disease resulting from mutation in the gene for vesicle‐associated membrane protein‐associated protein B. We evaluated a North American patient using exome sequencing,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e03ce3849789142ce04d6fabca36904
https://doi.org/10.1002/acn3.515
https://doi.org/10.1002/acn3.515
Autor:
Varun Takyar, Dara Bakar, Yaron Rotman, Stephen M. Hewitt, Chia-Ying Liu, Christopher Grunseich, Kenneth H. Fischbeck, Colleen Hadigan, Angela Kokkinis, Robert D. Guber, Ilona Kats, Derrick Fox, Hawwa Alao, Alan T. Remaley, David E. Kleiner
Publikováno v:
Neurology
Objective:To determine the prevalence and features of fatty liver disease in spinal and bulbar muscular atrophy (SBMA).Methods:Two groups of participants with SBMA were evaluated. In the first group, 22 participants with SBMA underwent laboratory ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14398b44b05a152bf326ffac61730e5
https://doi.org/10.1212/wnl.0000000000004748
https://doi.org/10.1212/wnl.0000000000004748
Autor:
Kenneth H. Fischbeck, Alice B. Schindler, Chad Heatwole, Angela Kokkinis, Robert D. Guber, Christopher Grunseich, Roxanna M. Bendixen
Publikováno v:
Muscle & Nerve
Introduction: The effects of spinal bulbar muscular atrophy (SBMA) on quality of life (QoL) are not well understood. This study describes symptoms from the patient's perspective, and the impact these symptoms have on QoL. Methods: We conducted open-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110fd1c77bcf1cee849e4ef93724983d
https://doi.org/10.1002/mus.25957
https://doi.org/10.1002/mus.25957
Publikováno v:
Critical Care Medicine. 49:663-663
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f7a528c9e11a352b5f06345775f01a3
https://doi.org/10.1097/01.ccm.0000731136.38116.cb
https://doi.org/10.1097/01.ccm.0000731136.38116.cb
Autor:
Christopher Grunseich, Ram Miller, Therese Swan, David J Glass, Mohamed El Mouelhi, Mara Fornaro, Olivier Petricoul, Igor Vostiar, Ronenn Roubenoff, Matthew N Meriggioli, Angela Kokkinis, Robert D Guber, Maher S Budron, John Vissing, Gianni Soraru, Tahseen Mozaffar, Albert Ludolph, John T Kissel, Kenneth H Fischbeck, Julia Dahlqvist, Nanna Witting, Ilaria Martinelli, Giorgia Querin, Namita A Goyal, Tiyonnoh M Cash, Brian Minton, Angela Rosenbohm, Ulrike Weiland, Patrick Weydt, Sharon Chelnick, Stanley Iyadurai, Wendy King
Publikováno v:
The Lancet. Neurology. 17(12)
Summary Background Spinal and bulbar muscular atrophy is an X-linked neuromuscular disease caused by CAG repeat expansion in the androgen receptor gene. Patients with this disease have low concentrations of insulin-like growth factor-1 (IGF-1), and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9881dd84f555fcde41505704071e3d8e
https://pubmed.ncbi.nlm.nih.gov/30337274
https://pubmed.ncbi.nlm.nih.gov/30337274
Autor:
Sander Kersten, Takamasa Inoue, Shengyi Sun, James C. Paton, John R. Yates, Xuemei Han, Takao Iwawaki, Xiling Shen, Kenneth W. Simpson, Robert D. Guber, Haoquan Wu, Guojun Shi, Yewei Ji, Adrienne W. Paton, Deyu Fang, Haibo Sha, Hongming Ma, Qiaoming Long, Hana Kim, Pengcheng Bu, Beixue Gao, Xin Shu, Ann-Hwee Lee, Gerald E. Duhamel, Ling Qi, Billy Tsai
Publikováno v:
Nature cell biology
Nature Cell Biology 17 (2015) 12
Nature Cell Biology, 17(12), 1546-1555
Nature Cell Biology 17 (2015) 12
Nature Cell Biology, 17(12), 1546-1555
Endoplasmic reticulum (ER)-associated degradation (ERAD) represents a principle quality control mechanism to clear misfolded proteins in the ER; however, its physiological significance and the nature of endogenous ERAD substrates remain largely unexp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9763dcaa3cf897e84c36df2ef4a4715d
https://doi.org/10.1038/ncb3266
https://doi.org/10.1038/ncb3266
Autor:
Robert D. Guber, Haibo Sha, Qiaoming Long, J. Thomas Brenna, Adam B. Francisco, Lei Liu, André Bensadoun, Peter Lawrence, Ling Qi, Muhammad Siyab Panhwar, Nicole Ehrhardt, Frits Mattijssen, Bingzhong Xue, Sander Kersten, Hang Shi, Zhen Xue, Shengyi Sun, Miklós Péterfy
Publikováno v:
Cell Metabolism 20 (2014) 3
Cell Metabolism, 20(3), 458-470
Cell Metabolism, 20(3), 458-470
SummarySel1L is an essential adaptor protein for the E3 ligase Hrd1 in the endoplasmic reticulum (ER)-associated degradation (ERAD), a universal quality-control system in the cell; but its physiological role remains unclear. Here we show that mice wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f376320335c6e78c7f3e9976c338f8