Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Robert D. Dayton"'
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 1, Pp 64-73 (2005)
Using a viral vector for mutant (P301L) tau, we studied the effects of gene transfer to the rat substantia nigra in terms of structural and functional properties of dopaminergic neurons. The mutant tau vector caused progressive loss of pars compacta
Externí odkaz:
https://doaj.org/article/a7585fbd8e21480fb8d6503c09d807c7
Autor:
Kasey L Jackson, Wen-Lang Lin, Sumitra Miriyala, Robert D Dayton, Manikandan Panchatcharam, Kevin J McCarthy, Monica Castanedes-Casey, Dennis W Dickson, Ronald L Klein
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169291 (2017)
One of the proteins most frequently found in neuropathological lesions is the ubiquitin binding protein p62 (sequestosome 1). Post-mortem analysis of p62 is a defining diagnostic marker in several neurodegenerative diseases including amyotrophic late
Externí odkaz:
https://doaj.org/article/3dee2022fb8c45f6b60958ecc55492be
Akademický článek
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Autor:
William M. Baldwin, Robert D. Dayton, Aaron W. Bivins, Rona S. Scott, Andrew D. Yurochko, John A. Vanchiere, Terry Davis, Connie L. Arnold, Jose.E.T. Asuncion, Mohammad A.N. Bhuiyan, Brandon Snead, William Daniel, Deborah G. Smith, Nicholas E. Goeders, Christopher G. Kevil, Jennifer Carroll, Kevin S. Murnane
Publikováno v:
Environmental Research. 222:115351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041f0ea94c1386a78effdf99db226c21
https://doi.org/10.1016/j.envres.2023.115351
https://doi.org/10.1016/j.envres.2023.115351
Autor:
Courtney N. Jamison, Kenneth E. McMartin, Brian Latimer, Hannah G. Mitchell, Robert D. Dayton, Mary P. McKinney
Publikováno v:
Clin Toxicol (Phila)
CONTEXT: Diethylene glycol (DEG) is an organic compound found in household products but also as an adulterant in medicines by acting as counterfeit solvent. DEG poisonings have been characterized predominately by acute kidney injury (AKI), but also b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef04088a3b5d9a3d93a9f64ffc5fc5d
https://doi.org/10.1080/15563650.2021.1874403
https://doi.org/10.1080/15563650.2021.1874403
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Widespread genetic modification of cells in the central nervous system (CNS) with a viral vector has become possible and increasingly more efficient. We previously applied an AAV9 vector with the cytomegalovirus/chicken beta-actin hybrid (CBA) promot
Externí odkaz:
https://doaj.org/article/02cb778cff0f4c5a97b168bf26e3940c
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
AAV9 has emerged as an efficient adeno-associated virus (AAV) serotype for gene transfer to the central nervous system. We have used this technique to study aspects of amyotrophic lateral sclerosis (ALS) by administering AAV encoding the ALS-related
Externí odkaz:
https://doaj.org/article/228dd4ace9214eb2939389fdba90db0f
Autor:
Hannah G. Mitchell, Mary P. McKinney, Brian Latimer, Courtney N. Jamison, Kenneth E. McMartin, Robert D. Dayton
Publikováno v:
Clin Toxicol (Phila)
Context Diethylene glycol (DEG) is an organic compound found in household products but also as a counterfeit solvent in medicines. DEG poisonings are characterized by acute kidney injury (AKI) and by neurological sequelae such as decreased reflexes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edbe6ec23b617f95f16bf722048d830
https://europepmc.org/articles/PMC9661884/
https://europepmc.org/articles/PMC9661884/
Autor:
Robert D. Dayton, Ronald Klein, Susmita Sarkar, Stephanie E. Tanninen, Kaori Takehara-Nishiuchi, Bardia Nouriziabari
Publikováno v:
Journal of Alzheimer's Disease. 63:725-740
Trace eyeblink conditioning is a hippocampus-dependent associative learning paradigm which is impaired in patients with Alzheimer's disease (AD) and animal AD models. Learning in this paradigm accompanies changes in oscillatory activity in forebrain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3430a06d7e1e2f6622653c00d9b0697f
https://doi.org/10.3233/jad-171033
https://doi.org/10.3233/jad-171033
Autor:
Ronald Klein, Robert D. Dayton, Mychal S. Grames, Xiao-Hong Lu, Kasey L. Jackson, Adam D. Richard
Publikováno v:
The FASEB Journal. 32:4420-4427
Recombinant adeno-associated virus (AAV) vectors are a popular genetic approach in neuroscience because they confer such efficient transgene expression in the brain and spinal cord. A number of studies have used AAV to express pathological disease-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dac5f0184f9a9a0b713de63623cb4f
https://doi.org/10.1096/fj.201701529rr
https://doi.org/10.1096/fj.201701529rr