Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Robert D. Bruno"'
Autor:
Martina Zamponi, Peter A. Mollica, Yara Khodour, Julie S. Bjerring, Robert D. Bruno, Patrick C. Sachs
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
We have previously shown that human and murine breast extracellular matrix (ECM) can significantly impact cellular behavior, including stem cell fate determination. It has been established that tissue-specific extracellular matrix from the central ne
Externí odkaz:
https://doaj.org/article/ebf6f577917c464b981c1a91673613af
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Standard three-dimensional (3D) in vitro culture techniques, such as those used for mammary epithelial cells, rely on random distribution of cells within hydrogels. Although these systems offer advantages over traditional 2D model
Externí odkaz:
https://doaj.org/article/875beeaad55440a08b782c6a10833273
Publikováno v:
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-11 (2017)
Abstract The accumulated evidence points to the microenvironment as the primary mediator of cellular fate determination. Comprised of parenchymal cells, stromal cells, structural extracellular matrix proteins, and signaling molecules, the microenviro
Externí odkaz:
https://doaj.org/article/6b4a55bc67084b68a546f9ee81438b44
Supplementary Figures 1-3, Tables 1-2 from Reprogramming Human Cancer Cells in the Mouse Mammary Gland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad5604dff36985fa3d1112e482b3161
https://doi.org/10.1158/0008-5472.22383426
https://doi.org/10.1158/0008-5472.22383426
The tissue microenvironment directs stem/progenitor cell behavior. Cancer cells are also influenced by the microenvironment. It has been shown that, when placed into blastocysts, cancer cells respond to embryonic cues and differentiate according to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357c47db70dec9db052e5949710fc16d
https://doi.org/10.1158/0008-5472.c.6500535
https://doi.org/10.1158/0008-5472.c.6500535
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-1 (2018)
Following publication of the original article [1], the authors reported a typesetting error in the spelling of the second author’s name.
Externí odkaz:
https://doaj.org/article/d8872fc0f0644722879ef2ceb6034355
Autor:
Elizabeth N. Booth-Creech, Shea M. Sullivan, Patrick C. Sachs, Robert D. Bruno, Xavier-Lewis Palmer, Martina Zamponi, Peter A. Mollica, John A. Reid
Publikováno v:
Acta Biomater
The extracellular matrix (ECM) of tissues is an important mediator of cell function. Moreover, understanding cellular dynamics within their specific tissue context is also important for developmental biology, cancer research, and regenerative medicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b5e237c714fa85c797ac93aeeff627
https://doi.org/10.1016/j.actbio.2019.06.017
https://doi.org/10.1016/j.actbio.2019.06.017
Autor:
Corinne A Boulanger, Robert D Bruno, David L Mack, Monica Gonzales, Nadia P Castro, David S Salomon, Gilbert H Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62019 (2013)
Experiments were conducted to redirect mouse Embryonic Stem (ES) cells from a tumorigenic phenotype to a normal mammary epithelial phenotype in vivo. Mixing LacZ-labeled ES cells with normal mouse mammary epithelial cells at ratios of 1:5 and 1:50 in
Externí odkaz:
https://doaj.org/article/42866e0bc41b4b1ba0cfd1a5bbfe8ba5
Publikováno v:
Mech Dev
Long-label retention has been used by many to prove Cairns’ immortal strand hypothesis and to identify potential stem cells. Here, we describe two strategies using 5-ethynl-2’-deoxyuridine (EdU) to identify and understand the distribution of long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b21e3d34430a7ac1c17a920a6b36cee
https://pubmed.ncbi.nlm.nih.gov/31336167
https://pubmed.ncbi.nlm.nih.gov/31336167
Autor:
Patrick C. Sachs, Nicole Northam, Robert D. Bruno, Xavier-Lewis Palmer, John A. Reid, Peter A. Mollica
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
The normal mammary microenvironment can suppress tumorigenesis and redirect cancer cells to adopt a normal mammary epithelial cell fate in vivo. Understanding of this phenomenon offers great promise for novel treatment and detection strategies in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b58c611ed2f7aae8e38c1eb59ba8a2
https://doi.org/10.1038/s41598-019-43922-z
https://doi.org/10.1038/s41598-019-43922-z