Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Robert D. Arnold"'
Autor:
Irene B. Vazquez Fuster, Amanda R. Taylor, Annette N. Smith, Sue H. Duran, William R. Ravis, Shanese L. Jasper, Robert D. Arnold
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 4, Pp 1563-1569 (2020)
Abstract Background Prolonged cytotoxic concentrations of cytarabine (CA) are required for maximum cytotoxicity. DepoCyt is a human liposomal cytarabine (LC) product that lasts longer in plasma and CSF compared with free CA (FC). The use of LC has no
Externí odkaz:
https://doaj.org/article/7c3801370dfc4426bede529a55a4420f
Autor:
Taraswi Mitra Ghosh, Jason White, Joshua Davis, Suman Mazumder, Teeratas Kansom, Elena Skarupa, Grafton S. Barnett, Gary A. Piazza, R. Curtis Bird, Amit K. Mitra, Clayton Yates, Brian S. Cummings, Robert D. Arnold
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Repetitive, low-dose (metronomic; METRO) drug administration of some anticancer agents can overcome drug resistance and increase drug efficacy in many cancers, but the mechanisms are not understood fully. Previously, we showed that METRO dosing of to
Externí odkaz:
https://doaj.org/article/78bf5631e26f44058e9dd33c413cb9f1
Autor:
Shelby C. Osburn, Paul A. Roberson, Jessica A. Medler, Jacob Shake, Robert D. Arnold, Nima Alamdari, Luke R. Bucci, Arianne Vance, Mastaneh Sharafi, Kaelin C. Young, Michael D. Roberts
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
The purpose of this study was to validate the efficacy of a customized vitamin-mineral supplement on blood biomarkers in pre-menopausal females. Women (21–40 years old) who were apparently healthy were recruited from the local community (ClinicalTr
Externí odkaz:
https://doaj.org/article/b087cc4db38248d18872bdb121a4bc70
Autor:
Ahmad H. Alhowail, Priyanka D. Pinky, Matthew Eggert, Jenna Bloemer, Lauren N. Woodie, Manal A. Buabeid, Subhrajit Bhattacharya, Shanese L. Jasper, Dwipayan Bhattacharya, Muralikrishnan Dhanasekaran, Martha Escobar, Robert D. Arnold, Vishnu Suppiramaniam
Publikováno v:
Heliyon, Vol 7, Iss 7, Pp e07456- (2021)
Doxorubicin (Dox) is a chemotherapeutic agent used widely to treat a variety of malignant cancers. However, Dox chemotherapy is associated with several adverse effects, including “chemobrain,” the observation that cancer patients exhibit through
Externí odkaz:
https://doaj.org/article/dfa5b2291c5f46db888c362442553cd6
Autor:
Manjusha Annaji, Ishwor Poudel, Sai H. S. Boddu, Robert D. Arnold, Amit K. Tiwari, R. Jayachandra Babu
Publikováno v:
Cancer Reports, Vol 4, Iss 3, Pp n/a-n/a (2021)
Abstract Background Resveratrol (3, 5, 4′‐trihydroxystilbene), a natural polyphenol and phytoalexin, has drawn considerable attention in the past decade due to its wide variety of therapeutic activities such as anticancer, anti‐inflammatory, an
Externí odkaz:
https://doaj.org/article/4d80c3d7e08947db80794ebe90d60426
Autor:
Hamad Alrbyawi, Ishwor Poudel, Manjusha Annaji, Sai H. S. Boddu, Robert D. Arnold, Amit K. Tiwari, R. Jayachandra Babu
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1128 (2022)
Daunorubicin (DNR) was delivered using a pH-sensitive liposomal system in B16-BL6 melanoma cell lines for enhanced cytotoxic effects. DNR was encapsulated within liposomes and CL as a component of the lipid bilayer. PEGylated pH-sensitive liposomes,
Externí odkaz:
https://doaj.org/article/0a65fed69e8e49a4a8af0ac22bb19d33
Autor:
Yueru Li, Yinghui Rong, Lisui Bao, Ben Nie, Guang Ren, Chen Zheng, Rajesh Amin, Robert D. Arnold, Ramesh B. Jeganathan, Kevin W. Huggins
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background Increased consumption of omega-3 (ω-3) fatty acids found in cold-water fish and fish oil has been reported to protect against obesity. A potential mechanism may be through reduction in adipocyte differentiation. Stearidonic acid
Externí odkaz:
https://doaj.org/article/dfca0a7188754f1c86a96188f3f3c6a4
Autor:
Cody T. Haun, Christopher G. Vann, Christopher B. Mobley, Paul A. Roberson, Shelby C. Osburn, Hudson M. Holmes, Petey M. Mumford, Matthew A. Romero, Kaelin C. Young, Jordan R. Moon, L. Bruce Gladden, Robert D. Arnold, Michael A. Israetel, Annie N. Kirby, Michael D. Roberts
Publikováno v:
Frontiers in Nutrition, Vol 5 (2018)
We examined hypertrophic outcomes of weekly graded whey protein dosing (GWP) vs. whey protein (WP) or maltodextrin (MALTO) dosed once daily during 6 weeks of high-volume resistance training (RT). College-aged resistance-trained males (training age =
Externí odkaz:
https://doaj.org/article/63f1cedbd3e149b49d4ff5e07d6c793d
Autor:
Ahmad H Alhowail, Matthew Eggert, Jenna Bloemer, Priyanka D Pinky, Lauren Woodie, Subhrajit Bhattacharya, Dwipayan Bhattacharya, Manal A Buabeid, Bruce Smith, Muralikrishnan Dhanasekaran, Gary Piazza, Miranda N Reed, Martha Escobar, Robert D Arnold, Vishnu Suppiramaniam
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294280 (2023)
Chemotherapy-induced memory loss ("chemobrain") can occur following treatment with the widely used chemotherapeutic agent doxorubicin (DOX). However, the mechanisms through which DOX induces cognitive dysfunction are not clear, and there are no comme
Externí odkaz:
https://doaj.org/article/ccf614b2e1554047a552692cd9b4ca07
Autor:
Jean M. Feugang, Ghassan M. Ishak, Matthew W. Eggert, Robert D. Arnold, Orion S. Rivers, Scott T. Willard, Peter L. Ryan, Eduardo L. Gastal
Publikováno v:
Theriogenology. 192:132-140
Despite the progress in assisted reproductive techniques, there is still a lack of rapid and minimally invasive in situ approaches for further enhancements of female fertility. Therefore, we synthesized clinically relevant liposome nanoparticles for