Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Robert D Stevens"'
Autor:
Chiara Robba, Romain Pirracchio, Raphaël Cinotti, Nicholas Fong, Jean Digitale, Gregory Burns, Julian Boesel, Robert D Stevens
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Introduction There is little consensus and high heterogeneity on the optimal set of relevant clinical outcomes in research studies regarding extubation in neurocritical care patients with brain injury undergoing mechanical ventilation. The aims of th
Externí odkaz:
https://doaj.org/article/38e6d15df3ec4e4fa4cbc9e133f599ff
Autor:
Shubhayu Bhattacharyay, Ioan Milosevic, Lindsay Wilson, David K Menon, Robert D Stevens, Ewout W Steyerberg, David W Nelson, Ari Ercole, CENTER-TBI investigators participants
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270973 (2022)
When a patient is admitted to the intensive care unit (ICU) after a traumatic brain injury (TBI), an early prognosis is essential for baseline risk adjustment and shared decision making. TBI outcomes are commonly categorised by the Glasgow Outcome Sc
Externí odkaz:
https://doaj.org/article/97b50c5106ae452994669df34ef857a0
Autor:
Melissa M Keenan, Beiyu Liu, Xiaohu Tang, Jianli Wu, Derek Cyr, Robert D Stevens, Olga Ilkayeva, Zhiqing Huang, Laura A Tollini, Susan K Murphy, Joseph Lucas, Deborah M Muoio, So Young Kim, Jen-Tsan Chi
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005599 (2015)
In order to propagate a solid tumor, cancer cells must adapt to and survive under various tumor microenvironment (TME) stresses, such as hypoxia or lactic acidosis. To systematically identify genes that modulate cancer cell survival under stresses, w
Externí odkaz:
https://doaj.org/article/0d3f4fffafb2491ca3549fa1521250a2
Autor:
Jesse F Gregory, Youngja Park, Yvonne Lamers, Nirmalya Bandyopadhyay, Yueh-Yun Chi, Kichen Lee, Steven Kim, Vanessa da Silva, Nikolas Hove, Sanjay Ranka, Tamer Kahveci, Keith E Muller, Robert D Stevens, Christopher B Newgard, Peter W Stacpoole, Dean P Jones
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e63544 (2013)
Marginal deficiency of vitamin B-6 is common among segments of the population worldwide. Because pyridoxal 5'-phosphate (PLP) serves as a coenzyme in the metabolism of amino acids, carbohydrates, organic acids, and neurotransmitters, as well as in as
Externí odkaz:
https://doaj.org/article/a4d251589e4f428ab4dda7dc474ccecb
Autor:
Bon Jeong Ku, Tae Hoon Kim, Jae Hee Lee, Eric D Buras, Lisa D White, Robert D Stevens, Olga R Ilkayeva, James R Bain, Christopher B Newgard, Francesco J DeMayo, Jae-Wook Jeong
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42915 (2012)
The disruption of cholesterol homeostasis leads to an increase in cholesterol levels which results in the development of cardiovascular disease. Mitogen Inducible Gene 6 (Mig-6) is an immediate early response gene that can be induced by various mitog
Externí odkaz:
https://doaj.org/article/0e6359e405594a9ba2f1da5581cf38fe
Autor:
Kim M Huffman, Leanne M Redman, Lawrence R Landerman, Carl F Pieper, Robert D Stevens, Michael J Muehlbauer, Brett R Wenner, James R Bain, Virginia B Kraus, Christopher B Newgard, Eric Ravussin, William E Kraus
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e28190 (2012)
To determine if caloric restriction (CR) would cause changes in plasma metabolic intermediates in response to a mixed meal, suggestive of changes in the capacity to adapt fuel oxidation to fuel availability or metabolic flexibility, and to determine
Externí odkaz:
https://doaj.org/article/02e6b7fb4190457b8721f0b5c8321b7b
Autor:
Brante P Sampey, Alex J Freemerman, Jimmy Zhang, Pei-Fen Kuan, Joseph A Galanko, Thomas M O'Connell, Olga R Ilkayeva, Michael J Muehlbauer, Robert D Stevens, Christopher B Newgard, Heather A Brauer, Melissa A Troester, Liza Makowski
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38812 (2012)
Obesity has reached epidemic proportions worldwide. Several animal models of obesity exist, but studies are lacking that compare traditional lard-based high fat diets (HFD) to "Cafeteria diets" (CAF) consisting of nutrient poor human junk food. Our p
Externí odkaz:
https://doaj.org/article/8123c07fdc0d45b6ac1702b037a95c4d
Autor:
Christine T Ferrara, Ping Wang, Elias Chaibub Neto, Robert D Stevens, James R Bain, Brett R Wenner, Olga R Ilkayeva, Mark P Keller, Daniel A Blasiole, Christina Kendziorski, Brian S Yandell, Christopher B Newgard, Alan D Attie
Publikováno v:
PLoS Genetics, Vol 4, Iss 3, p e1000034 (2008)
Although numerous quantitative trait loci (QTL) influencing disease-related phenotypes have been detected through gene mapping and positional cloning, identification of the individual gene(s) and molecular pathways leading to those phenotypes is ofte
Externí odkaz:
https://doaj.org/article/48e820b028a54bf79bb5efbff00034d9
Surviving critical illness is not always the happy ending we imagine for patients. Many ICU survivors suffer from a range of long-lasting physical and psychological issues such end stage renal disease, congestive heart failure, cognitive impairment,
Autor:
Shiker S. Nair, Alina Guo, Joseph Boen, Ataes Aggarwal, Ojas Chahal, Arushi Tandon, Meer Patel, Sreenidhi Sankararaman, Robert D. Stevens
ObjectiveIntracranial pressure (ICP) is a vital waveform used to assess the conditions of patients with intracranial pathologies, such as traumatic brain injury. The current standard for monitoring ICP requires a catheter to be inserted into the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::489e7bb18090cba0a9926fc532725eb2
https://doi.org/10.1101/2023.05.16.23289747
https://doi.org/10.1101/2023.05.16.23289747