Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate.

Autor: Maria Traka, Amy V Gasper, Antonietta Melchini, James R Bacon, Paul W Needs, Victoria Frost, Andrew Chantry, Alexandra M E Jones, Catharine A Ortori, David A Barrett, Richard Y Ball, Robert D Mills, Richard F Mithen

Publikováno v: PLoS ONE, Vol 3, Iss 7, p e2568 (2008)

Epidemiological studies suggest that people who consume more than one portion of cruciferous vegetables per week are at lower risk of both the incidence of prostate cancer and of developing aggressive prostate cancer but there is little understanding

Externí odkaz: https://doaj.org/article/df0dbabdba7a4c4f89a2615f4c02582b

The Urine Biomarker PUR-4 Is Positively Associated with the Amount of Gleason 4 in Human Prostate Cancers

Autor: Jeremy Clark, Mark Simon Winterbone, Colin Cooper, Rachel Hurst, Lauren D'Sa, Robert D. Mills, Chris Parker, Marcelino Yazbek Hanna, Daniel Brewer, Richard Y. Ball, Ryan Cardenas

Publikováno v: Life
Volume 11
Issue 11
Life, Vol 11, Iss 1172, p 1172 (2021)

The Prostate Urine Risk (PUR) biomarker is a four-group classifier for predicting outcome in patients prior to biopsy and for men on active surveillance. The four categories correspond to the probabilities of the presence of normal tissue (PUR-1), D�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6335fbb1668ac7d63bda52527d2393a9

Integration of urinary EN2 protein & cell-free RNA data in the development of a multivariable risk model for the detection of prostate cancer prior to biopsy

Autor: Jeremy Clark, Daniel Brewer, Shea P. Connell, Colin Cooper, Robert D. Mills, Richard Morgan, Hardev Pandha

Publikováno v: Cancers
Cancers, Vol 13, Iss 2102, p 2102 (2021)

Simple Summary Prostate cancer is a disease responsible for a large proportion of all male cancer deaths but there is a high chance that a patient will die with the disease rather than from. Therefore, there is a desperate need for improvements in di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f8bb740d14d624e11471bf0f2813d5
https://ueaeprints.uea.ac.uk/id/eprint/79899/

Methodology for the at-home collection of urine samples for prostate cancer detection

Autor: Colin Cooper, Ingrid Jenny Guldvik, Shea P. Connell, Rachel Hurst, Malgorzata Palczynska, Jeremy Clark, Kate Manley, Robert D. Mills, Martyn Webb, Ian G. Mills, Daniel Brewer, Mireia Olivan

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Webb, M, Manley, K, Olivan, M, Guldvik, I, Palczynska, M, Hurst, R, Connell, S P, Mills, I G, Brewer, D S, Mills, R, Cooper, C S & Clark, J 2019, ' Methodology for the at-home collection of urine samples for prostate cancer detection ', BioTechniques . https://doi.org/10.2144/btn-2019-0092

Urine from patients with prostate cancer (PCa) contains gene transcripts that have been used for PCa diagnosis and prognosis. Historically, patient urine samples have been collected after a digital rectal examination of the prostate, which was though

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dce1acb3e849c8d12f5128f6e2b1c57
http://hdl.handle.net/2445/169203

Exercise-induced attenuation of treatment side-effects in patients with newly diagnosed prostate cancer beginning androgen-deprivation therapy: a randomised controlled trial

Autor: Robert D. Mills, Mark Rochester, Samuel T. Orange, Alasdair F. O'Doherty, John M. Saxton, Anthony S. Leicht, Wilphard Ndjavera

Publikováno v: BJU internationalReferences. 125(1)

Objectives: (i) To assess whether exercise training attenuates the adverse effects of treatment in patients with newly diagnosed prostate cancer beginning androgen-deprivation therapy (ADT), and (ii) to examine whether exercise-induced improvements a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3099a10a3ab57b8cf8f0bf2bf125057
https://pubmed.ncbi.nlm.nih.gov/31605663