Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Robert D, Stevens"'
Autor:
Shubhayu Bhattacharyay, Pier Francesco Caruso, Cecilia Åkerlund, Lindsay Wilson, Robert D. Stevens, David K. Menon, Ewout W. Steyerberg, David W. Nelson, Ari Ercole, the CENTER-TBI investigators and participants
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Existing methods to characterise the evolving condition of traumatic brain injury (TBI) patients in the intensive care unit (ICU) do not capture the context necessary for individualising treatment. Here, we integrate all heterogenous data st
Externí odkaz:
https://doaj.org/article/658b564643594c16b2584d0096c8e4c3
Autor:
Sarah Wahlster, Monisha Sharma, Shaurya Taran, James A. Town, Robert D. Stevens, Raphaël Cinotti, Karim Asehoune, Paolo Pelosi, Chiara Robba, ENIO Study Group Collaborators
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-16 (2023)
Abstract Background There is insufficient evidence to guide ventilatory targets in acute brain injury (ABI). Recent studies have shown associations between mechanical power (MP) and mortality in critical care populations. We aimed to describe MP in v
Externí odkaz:
https://doaj.org/article/06775a52f7f84b2e8942ada75caa1d75
Autor:
Chiara Robba, Romain Pirracchio, Raphaël Cinotti, Nicholas Fong, Jean Digitale, Gregory Burns, Julian Boesel, Robert D Stevens
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Introduction There is little consensus and high heterogeneity on the optimal set of relevant clinical outcomes in research studies regarding extubation in neurocritical care patients with brain injury undergoing mechanical ventilation. The aims of th
Externí odkaz:
https://doaj.org/article/38e6d15df3ec4e4fa4cbc9e133f599ff
Autor:
Andrea I. Luppi, Joana Cabral, Rodrigo Cofre, Pedro A.M. Mediano, Fernando E. Rosas, Abid Y. Qureshi, Amy Kuceyeski, Enzo Tagliazucchi, Federico Raimondo, Gustavo Deco, James M. Shine, Morten L. Kringelbach, Patricio Orio, ShiNung Ching, Yonatan Sanz Perl, Michael N. Diringer, Robert D. Stevens, Jacobo Diego Sitt
Publikováno v:
NeuroImage, Vol 275, Iss , Pp 120162- (2023)
Disorders of consciousness are complex conditions characterised by persistent loss of responsiveness due to brain injury. They present diagnostic challenges and limited options for treatment, and highlight the urgent need for a more thorough understa
Externí odkaz:
https://doaj.org/article/fc2682b4006f431f83d6438f1b9584ed
Autor:
Sarah E. Nelson, Jose I. Suarez, Alexander Sigmon, Jun Hua, Casey Weiner, Haris I. Sair, Robert D. Stevens
Publikováno v:
Neurological Research and Practice, Vol 4, Iss 1, Pp 1-7 (2022)
Abstract Purpose External ventricular drains (EVD) are commonly used in aneurysmal subarachnoid hemorrhage (aSAH) patients and can be life-saving by diverting cerebrospinal fluid. However, the overall relationship between EVD use and outcome is poorl
Externí odkaz:
https://doaj.org/article/22a5067ee5d74aeaa0a4233f777db8eb
Autor:
Alec G. Trub, Gregory R. Wagner, Kristin A. Anderson, Scott B. Crown, Guo-Fang Zhang, J. Will Thompson, Olga R. Ilkayeva, Robert D. Stevens, Paul A. Grimsrud, Rhushikesh A. Kulkarni, Donald S. Backos, Jordan L. Meier, Matthew D. Hirschey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Statin therapy is associated with numerous cellular effects. Here, the authors show that statin treatment increases post-translational modifications on fatty acid synthase in the active site, revealing communication between the cholesterol and lipid
Externí odkaz:
https://doaj.org/article/6da5de5206424c06a24ccdd0b2b403ff
Autor:
Shubhayu Bhattacharyay, John Rattray, Matthew Wang, Peter H. Dziedzic, Eusebia Calvillo, Han B. Kim, Eshan Joshi, Pawel Kudela, Ralph Etienne-Cummings, Robert D. Stevens
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Our goal is to explore quantitative motor features in critically ill patients with severe brain injury (SBI). We hypothesized that computational decoding of these features would yield information on underlying neurological states and outcome
Externí odkaz:
https://doaj.org/article/4a186e855583415e958f502e895821dd
Surviving critical illness is not always the happy ending we imagine for patients. Many ICU survivors suffer from a range of long-lasting physical and psychological issues such end stage renal disease, congestive heart failure, cognitive impairment,
Autor:
Anil K. Palepu, Aditya Murali, Jenna L. Ballard, Robert Li, Samiksha Ramesh, Hieu Nguyen, Hanbiehn Kim, Sridevi Sarma, Jose I. Suarez, Robert D. Stevens
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Traumatic brain injury (TBI) is a leading neurological cause of death and disability across the world. Early characterization of TBI severity could provide a window for therapeutic intervention and contribute to improved outcome. We hypothes
Externí odkaz:
https://doaj.org/article/8e1932ab8403438ba6b918f49dfeab32
Autor:
Rui Wang, Chengyan Chu, Zhiliang Wei, Lin Chen, Jiadi Xu, Yajie Liang, Miroslaw Janowski, Robert D. Stevens, Piotr Walczak
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background Cell transplantation-based treatments for neurological disease are promising, yet graft rejection remains a major barrier to successful regenerative therapies. Our group and others have shown that long-lasting tolerance of transpl
Externí odkaz:
https://doaj.org/article/46b259a4337b422788c1b17cbe55e20c