Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Robert D, Ladner"'
Autor:
Craig Davison, Roisin Morelli, Catherine Knowlson, Melanie McKechnie, Robbie Carson, Xanthi Stachtea, Kylie A. McLaughlin, Vivien E. Prise, Kienan Savage, Richard H. Wilson, Karl A. Mulligan, Peter M. Wilson, Robert D. Ladner, Melissa J. LaBonte
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Triple-negative breast cancer (TNBC) remains the most lethal breast cancer subtype with poor response rates to the current chemotherapies and a lack of additional effective treatment options. We have identified deoxyuridine 5′-triphosphate
Externí odkaz:
https://doaj.org/article/d3cd97feebf847539e7f6183d26a60c8
Chemotherapies that target thymidylate synthase (TS) continue to see considerable clinical expansion in non–small cell lung cancer (NSCLC). One drawback to TS-targeted therapies is drug resistance and subsequent treatment failure. Novel therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2089c13f6765ad5f92362f53a9b5fb29
https://doi.org/10.1158/1535-7163.c.6535269.v1
https://doi.org/10.1158/1535-7163.c.6535269.v1
Autor:
Heinz-Josef Lenz, Robert D. Ladner, Nicos A. Petasis, Stan G. Louie, Kalyan C. Nagulapalli Venkata, David O. Rosenberg, David Paez, Leonor Benhaim, Dongyun Yang, Armin Gerger, Pierre O. Bohanes, Wu Zhang, Melissa J. Labonte, Yan Ning
Colorectal cancer is the second most common cause of cancer-related death in the United States. Recent studies showed that interleukin-8 (IL-8) and its receptors (CXCR1 and CXCR2) are significantly upregulated in both the tumor and its microenvironme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8701c959f80be42b6a03a73a6f759053
https://doi.org/10.1158/1535-7163.c.6536059
https://doi.org/10.1158/1535-7163.c.6536059
Autor:
Heinz-Josef Lenz, Robert D. Ladner, Nicos A. Petasis, Stan G. Louie, Kalyan C. Nagulapalli Venkata, David O. Rosenberg, David Paez, Leonor Benhaim, Dongyun Yang, Armin Gerger, Pierre O. Bohanes, Wu Zhang, Melissa J. Labonte, Yan Ning
PDF file, 5.9MB, Clonogenicity assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91517df17e6912e6fa6cf0c909094ee
https://doi.org/10.1158/1535-7163.22499077
https://doi.org/10.1158/1535-7163.22499077
Autor:
Heinz-Josef Lenz, Robert D. Ladner, Nicos A. Petasis, Stan G. Louie, Kalyan C. Nagulapalli Venkata, David O. Rosenberg, David Paez, Leonor Benhaim, Dongyun Yang, Armin Gerger, Pierre O. Bohanes, Wu Zhang, Melissa J. Labonte, Yan Ning
PDF file, 770K, SCH-527123 treatment inhbits downstream activation of CXCR2 by decreasing phosphoryaltion of NF-kB and MAPK signaling cascades in CRC cell line models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3e16eaef6ebb00fae960718e4e13f0
https://doi.org/10.1158/1535-7163.22499080.v1
https://doi.org/10.1158/1535-7163.22499080.v1