Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Robert Coopersmith"'
Autor:
Robert Coopersmith, Rachael L. Neve
Publikováno v:
BioTechniques, Vol 27, Iss 6, Pp 1156-1160 (1999)
The study of protein-protein interactions in the nervous system has become dependent on the ability to express foreign proteins (or to overexpress endogenous proteins) within neurons. Often, multiple genes need to be overexpressed in the same cell. T
Externí odkaz:
https://doaj.org/article/9a012f3f5c814fec99ab6bb53d8c0229
Autor:
Rachael L. Neve, Kathryn J. Ivins, Donna L. McPhie, Robert Coopersmith, Michael R. Kozlowski, Kim A. Neve, Susan P. Manly, Yuzhi Chen, Andrew Hines-Peralta
Publikováno v:
The Journal of Neuroscience. 23:6914-6927
Apoptotic pathways and DNA synthesis are activated in neurons in the brains of individuals with Alzheimer disease (AD). However, the signaling mechanisms that mediate these events have not been defined. We show that expression of familial AD (FAD) mu
Autor:
Rachael L. Neve, Robert Coopersmith
Publikováno v:
BioTechniques. 27:1156-1160
The study of protein-protein interactions in the nervous system has become dependent on the ability to express foreign proteins (or to overexpress endogenous proteins) within neurons. Often, multiple genes need to be overexpressed in the same cell. T
Autor:
Donna L. McPhie, Curran J. Murphy, Robert Coopersmith, Rachael L. Neve, Christopher Santeufemio, Kara G. Pratt, Stephanie D. Lynn
Publikováno v:
The Journal of Neuroscience. 18:7757-7767
Structural plasticity of nerve cells is a requirement for activity-dependent changes in the brain. The growth-associated protein GAP-43 is thought to be one determinant of such plasticity, although the molecular mechanism by which it mediates dynamic
Autor:
Robert Coopersmith, Michael Leon
Publikováno v:
Brain Research. 674:230-237
The olfactory bulb exhibits high glycogen phosphorylase activity, the rate-limiting enzyme in the mobilization of glycogen. The bulb also receives dense noradrenergic innervation and noradrenaline is known to stimulate glycogen breakdown. We determin
Publikováno v:
Neurochemical Research. 16:475-481
The activity of glucose-6-phosphate dehydrogenase, the rate-limiting enzyme of the hexose monophosphate shunt, was examined in olfactory epithelium, respiratory epithelium, olfactory bulb, and occipital cortex in Fisher 344 rats aged 4 and 24 months.
Publikováno v:
Brain Research. 543:341-346
Olfactory receptor neurons are a CNS entry point for a wide variety of airborne substances. Therefore, it is probable that detoxification mechanisms are present in these neurons to neutralize such agents. Glutathione (GSH) is an essential component o
Autor:
Jonathan Rees, Yelena Eltsefon, Michael P. Cary, Patrick Wieghardt, David Rose, Chris Sander, John J. Hunter, Joel Pradines, Laura A. Rudolph-Owen, Steve Rowley, Alan Ruttenberg, Patrick J. LeRoy, Vlado Dančík, Christophe Leroy, Victor Farutin, Robert Coopersmith, Christian G. Reich
Publikováno v:
Journal of biopharmaceutical statistics. 14(3)
We present a new computational method for identifying regulated pathway components in transcript profiling (TP) experiments by evaluating transcriptional activity in the context of known biological pathways. We construct a graph representing thousand
Autor:
Robert Coopersmith, Charles Otis Adler
Publikováno v:
13th Applied Aerodynamics Conference.
Autor:
Robert Coopersmith, Charles Otis Adler
Publikováno v:
13th Applied Aerodynamics Conference.