Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Robert Cedergren"'
Autor:
Robert Cedergren, Nicolas Cermakian
This chapter evaluates the distribution of modified nucleosides in certain RNA species of the three domains of life (archaea, bacteria, and eukaryotes). Fourteen modifications are present in all three domains and of these several are found at compara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6116d24febc9b6182099329e8bd8574
https://doi.org/10.1128/9781555818296.ch29
https://doi.org/10.1128/9781555818296.ch29
Publikováno v:
Molecular and Biochemical Parasitology. 113:261-269
Nearly all mitochondrial RNA polymerase genes identified to date are encoded in the nucleus and have similarities to T3 and T7 bacteriophage RNA polymerases. Some chloroplast genes are also transcribed by T3/T7 phage-like RNA polymerases, raising the
Publikováno v:
Genome Research. 10:1011-1019
Hammerhead ribozymes previously were found in satellite RNAs from plant viroids and in repetitive DNA from certain species of newts and schistosomes. To determine if this catalytic RNA motif has a wider distribution, we decided to scrutinize the GenB
Autor:
Robert Cedergren, Jamie K. Scott, Sergey V. Steinberg, Pilar Blancafort, Bruno Paquin, Roscoe Klinck
Publikováno v:
Chemistry & Biology. 6:585-597
Background: The zinc finger (ZF) is the most abundant nucleic-acid-interacting protein motif. Although the interaction of ZFs with DNA is reasonably well understood, little is known about the RNA-binding mechanism. We investigated RNA binding to ZFs
Autor:
Robert Cedergren, Edouard Bertrand, Maurille J. Fournier, Dmitry Samarsky, Robert H. Singer, Gerardo Ferbeyre
Publikováno v:
Proceedings of the National Academy of Sciences. 96:6609-6614
A hammerhead ribozyme has been localized to the yeast nucleolus by using the U3 small nucleolar RNA as a carrier. The hybrid small nucleolar RNA:ribozyme, designated a “snorbozyme,” is metabolically stable and cleaves a target U3 RNA with nearly
Autor:
Gertraud Burger, Bernd Lang, G. B. Golding, Michael W. Gray, Claude Lemieux, Monique Turmel, David Sankoff, Robert Cedergren
Publikováno v:
The Biological Bulletin. 196:400-403
Program in Evolutionary Biology, Canadian Institute for Advanced Research, ‘Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia, Canada; *Departement de biochimie et 5Centre de recherches mathematiques, Universite’ de Montreal,
Autor:
Robert Cedergren, Gerardo Ferbeyre, Rémi Emond, Véronique Bourdeau, Nicolas Cermakian, Sergey V. Steinberg
Publikováno v:
Proceedings of the National Academy of Sciences. 95:1375-1380
The “cloverleaf” base-pairing pattern was established as the structural paradigm of active tRNA species some 30 years ago. Nevertheless, this pattern does not accommodate the folding of certain mitochondrial tRNAs. For these recalcitrant tRNAs, w
Autor:
Isabelle Plante, Diane Saint-Louis, Monique Turmel, David Sankoff, G. Brian Golding, Michael W. Gray, Claude Lemieux, Gertraud Burger, Eric Delage, Robert Cedergren, B. Franz Lang, Yun Zhu, Pierre A. Rioux, Tim G. Littlejohn, Nicolas Brossard
Publikováno v:
Nucleic Acids Research. 26:865-878
Although the collection of completely sequenced mitochondrial genomes is expanding rapidly, only recently has a phylogenetically broad representation of mtDNA sequences from protists (mostly unicellular eukaryotes) become available. This review surve
Publikováno v:
Nature Biotechnology. 15:432-435
We have evaluated inhibition of the plasmid-born chloramphenicol acetyl transferase gene (CAT) by the hammerhead ribozyme and antisense RNA in Escherichia coli where the translation and transcription rates have been modified. Whereas neither antisens
Publikováno v:
Journal of Molecular Biology. 266:269-282
The mitochondrial tRNAs (mtRNA) of five distinct, secondary structure types have been identified in the tRNA sequence compilation, and the three-dimensional modeling for representative sequences of these types has been carried out using a new criteri