Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Robert Cardiff"'
1
Akademický článek
Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes
Autor: Won Kyung Kim, Adam W. Olson, Jiaqi Mi, Jinhui Wang, Dong-Hoon Lee, Vien Le, Alex Hiroto, Joseph Aldahl, Christian H. Nenninger, Alyssa J. Buckley, Robert Cardiff, Sungyong You, Zijie Sun
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Activation of the androgen receptor (AR) through androgen binding is essential for prostate tumorigenesis. Here the authors show that AR activation in a subpopulation of prostatic progenitor cells can initiate prostatic intraepithelial neoplasia form
Externí odkaz: https://doaj.org/article/41964beab6684388acb4a29f190f0143
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2
Akademický článek
Single unpurified breast tumor-initiating cells from multiple mouse models efficiently elicit tumors in immune-competent hosts.
Autor: Natasza A Kurpios, Adele Girgis-Gabardo, Robin M Hallett, Stephen Rogers, David W Gludish, Lisa Kockeritz, James Woodgett, Robert Cardiff, John A Hassell
Publikováno v: PLoS ONE, Vol 8, Iss 3, p e58151 (2013)
The tumor-initiating cell (TIC) frequency of bulk tumor cell populations is one of the criteria used to distinguish malignancies that follow the cancer stem cell model from those that do not. However, tumor-initiating cell frequencies may be influenc
Externí odkaz: https://doaj.org/article/70d30803d5c14f6c903339ecc6b17fc7
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6
Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes
Autor: Won Kyung Kim, Adam W. Olson, Jiaqi Mi, Jinhui Wang, Dong-Hoon Lee, Vien Le, Alex Hiroto, Joseph Aldahl, Christian H. Nenninger, Alyssa J. Buckley, Robert Cardiff, Sungyong You, Zijie Sun
Publikováno v: Nature communications. 13(1)
Androgen/androgen receptor (AR) signaling pathways are essential for prostate tumorigenesis. However, the fundamental mechanisms underlying the AR functioning as a tumor promoter in inducing prostatic oncogenesis still remain elusive. Here, we demons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b69e3a0c6b0a3b4e8780d2bcb61da70
https://pubmed.ncbi.nlm.nih.gov/35902588
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7
Abstract LB-200: Loss of the scaffold protein Kibra in a mouse model of triple-negative breast cancer
Autor: Jennifer France Knight, Tina Gruosso, Danielle Angeline de Verteuil, Sadiq Saleh, Robert Lesurf, Hong Zhao, Ryan Davis, Dongmei Zuo, Robert Cardiff, Jeffrey Gregg, Michael Hallett, Morag Park
Publikováno v: Cancer Research. 75:LB-200
Introduction: Targeted therapies in breast cancer rely on tumor cell expression of Estrogen and/or HER2 receptors. Triple negative breast cancers (TNBCs), lacking these receptors, have no targeted therapies. We have developed a preclinical murine mod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6845f0a3763d50e46c142a9b6c845bc6
https://doi.org/10.1158/1538-7445.am2015-lb-200
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8
SU-EE-A4-06: Longitudinal Correlations in a Small-Animal PET Studies
Autor: Simon R Cherry, Robert Cardiff, E. Mcgoldrick, Alexander D Borowsky, Craig K. Abbey, Jeffrey Gregg
Publikováno v: Medical Physics. 32:1901-1901
Purpose: One area of interest in the rapidly developing field of small‐animal imaging is preclinical evaluations of cancertherapeutics. It is clear that longitudinal imaging studies reduce the number of animals necessary for such evaluations by fol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e79cf20b9253e357d004339d82e0458e
https://doi.org/10.1118/1.1997470
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