Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Robert C. Sonders"'
1
Simultaneous determination of clarithromycin and 14(R)-hydroxyclarithromycin in plasma and urine using high-performance liquid chromatography with electrochemical detection
Autor: Lawrence T. Sennello, Robert C. Sonders, Sou-Yie Chu
Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications. 571:199-208
A sensitive method for the simultaneous high-performance liquid chromatographic determination of clarithromycin and its active metabolite in plasma and urine is described. Alkalinized samples were coextracted with an internal standard and analyzed on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3989053ac3d47a76328d988429fcf5f
https://doi.org/10.1016/0378-4347(91)80446-j
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2
Simultaneous Analysis of the Single and Multiple Dose Pharmacokinetics of the Non-Steroidal Anti-Inflammatory, Alclofenac
Autor: Nadav Friedmann, William G Jochimsen, Lawrence T. Sennello, Robert C. Sonders
Publikováno v: Journal of International Medical Research. 7:253-262
Two clinical studies were conducted to study the pharmacokinetics of alclofenac in healthy adult male volunteers when the drug was administered in both single and multiple dosing regimens. The first study involved the participation of thirty-two subj
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0573881c5f62311d08bdaa7b75c9e85f
https://doi.org/10.1177/030006057900700401
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3
Cefsulodin kinetics in healthy subjects after intramuscular and intravenous injection
Autor: Elizabeth W Thomas, Robert C. Sonders, G. Richard Granneman, Lawrence T. Sennello, Beverly Wynne
Publikováno v: Clinical Pharmacology and Therapeutics. 31:95-103
We evaluated cefsulodin kinetics in normal subjects after 250-, 500-, and 1,000-mg, intramuscular injections and 500-, 1,000-, and 2,000-mg 30-min intravenous infusions. Twelve plasma and four urine samples were collected in the first 12 and 24 hr. P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bde266d5b4ad956cfea7e703ec0dd0
https://doi.org/10.1038/clpt.1982.15
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5
Toxicological aspects of cyclamate and cyclohexylamine
Autor: Barbara A. Bopp, Robert C. Sonders, James W. Kesterson, A. G. Renwick
Publikováno v: CRC Critical Reviews in Toxicology. 16:213-306
In the late 1960s the artificial sweetener cyclamate was implicated as a bladder carcinogen in rats. This finding and other concerns about its safety ultimately led to a ban on cyclamate in the U.S. and restrictions on its use in many other countries
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e79bcab55411bfde001dc140f39738
https://doi.org/10.3109/10408448609037465
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7
Excretion of Cyclamate in the Rat
Autor: J C Netwal, Robert C. Sonders, R G Wiegand
Publikováno v: Journal of AOAC INTERNATIONAL. 51:136-140
The utility of the gas chromatographic procedure for cyclamate has been confirmed. 14C-cyclamate was traced through the procedure to determine distribution at each step. The recovery of dietary cyclamate in excreta of the rat was found to be complete
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d2e2307e3c809c45bd4c5099f0befc4
https://doi.org/10.1093/jaoac/51.1.136
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9
Metabolic fate of selected selenium compounds in laboratory animals and man
Autor: Robert C. Sonders, Barbara A. Bopp, James W. Kesterson
Publikováno v: Drug metabolism reviews. 13(2)
(1982). Metabolic Fate of Selected Selenium Compounds in Laboratory Animals and Man. Drug Metabolism Reviews: Vol. 13, No. 2, pp. 271-318.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3d0eeb8ac6cf95680ba01bc36a1cbc
https://pubmed.ncbi.nlm.nih.gov/7047128
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