Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robert C. Peery"'
Autor:
Jian-Ting Zhang, Jing-Yuan Liu, Shaobo Zhang, Robert C. Peery, Jianguo Liu, Zizheng Dong, Jing Qi
Many oncoproteins are considered undruggable because they lack enzymatic activities. In this study, we present a small-molecule–based anticancer agent that acts by inhibiting dimerization of the oncoprotein survivin, thereby promoting its degradati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f2e36d965c6eb35195e2eebe7cf543
https://doi.org/10.1158/0008-5472.c.6507885
https://doi.org/10.1158/0008-5472.c.6507885
Autor:
Jian-Ting Zhang, Jing-Yuan Liu, Shaobo Zhang, Robert C. Peery, Jianguo Liu, Zizheng Dong, Jing Qi
Effect of compounds from in-silico screening on cancer cell survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1094aa0d0831812d0fa5947844b3fd51
https://doi.org/10.1158/0008-5472.22409976.v1
https://doi.org/10.1158/0008-5472.22409976.v1
Publikováno v:
Seminars in perinatology. 45(6)
The interaction between the gut and its eventual trillions of microbe inhabitants during microbial colonization, represents a critical time period for establishing the overall health and wellbeing of an individual. The gut microbiome represents a div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3d97a5dbe1cda8441fdc8d16cb799a
https://pubmed.ncbi.nlm.nih.gov/34246487
https://pubmed.ncbi.nlm.nih.gov/34246487
Autor:
Jing-Yuan Liu, Jian Ting Zhang, Robert C. Peery, Pedro de Andrade Horn, Kwaku Kyei-Baffour, Jianguo Liu, Zizheng Dong, Mingji Dai
Publikováno v:
J Med Chem
Survivin, a homodimeric member of the Inhibitor of Apoptosis Protein (IAP) family, is required for cancer cell survival and overexpressed in almost all solid tumors. However, targeting survivin has been challenging due to its "undruggable" nature. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bea68b8b6f4d3a1c5405891f77f6227
https://pubmed.ncbi.nlm.nih.gov/32421328
https://pubmed.ncbi.nlm.nih.gov/32421328
Publikováno v:
Drug Discovery Today. 22:1466-1477
Survivin, the smallest member of the inhibitor of apoptosis protein (IAP) family, is overexpressed in cells of almost all cancers but not in most normal tissues in adults. Survivin expression is required for cancer cell survival and knocking down its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a5329e78160c36a557e669882e16a0
https://doi.org/10.1016/j.drudis.2017.05.009
https://doi.org/10.1016/j.drudis.2017.05.009
Autor:
Jing Qi, Robert C. Peery, Jianguo Liu, Jian Ting Zhang, Jing-Yuan Liu, Zizheng Dong, Shaobo Zhang
Publikováno v:
Cancer research. 78(24)
In the original version of [this article][1] ([1][2]), the Western blot image in Fig. 4F was inadvertently taken from the results of a different experiment. The authors provided the Western blot image from the correct experiment and the error has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68038ceee9f5b95f2456c4a0e1514487
https://pubmed.ncbi.nlm.nih.gov/26744521
https://pubmed.ncbi.nlm.nih.gov/26744521
Autor:
Robert C. Peery
Publikováno v:
Cancer Research. 78:4396-4396
Despite therapeutic advancements, castration-resistant prostate cancer (CRPC) remains the second most common cause of cancer-related mortality in men. Docetaxel is the first cytotoxic agent to show modest improvements in overall survival rate in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952174c8927bf3434a0e64296fd719df
https://doi.org/10.1158/1538-7445.am2018-4396
https://doi.org/10.1158/1538-7445.am2018-4396
Autor:
Jianguo Liu, Jing Qi, Zizheng Dong, Shaobo Zhang, Jian Ting Zhang, Robert C. Peery, Jing-Yuan Liu
Publikováno v:
Cancer research. 76(2)
Many oncoproteins are considered undruggable because they lack enzymatic activities. In this study, we present a small-molecule–based anticancer agent that acts by inhibiting dimerization of the oncoprotein survivin, thereby promoting its degradati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f3f67df20664a7af52b1089f52258a
https://pubmed.ncbi.nlm.nih.gov/30552122
https://pubmed.ncbi.nlm.nih.gov/30552122