Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Robert C. Klipp"'
Publikováno v:
eLife, Vol 12 (2023)
Acid-sensing ion channels (ASICs) are trimeric proton-gated sodium channels. Recent work has shown that these channels play a role in necroptosis following prolonged acidic exposure like occurs in stroke. The C-terminus of ASIC1a is thought to mediat
Externí odkaz:
https://doaj.org/article/217688c146a2459fb987c3950f921eef
Autor:
Robert C. Klipp, John R. Bankston
Publikováno v:
Biophysical Journal. 122:394a-395a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::244c95c6d639a872076b913e66cb4615
https://doi.org/10.1016/j.bpj.2022.11.2155
https://doi.org/10.1016/j.bpj.2022.11.2155
Publikováno v:
Channels
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Acid-sensing ion channels (ASICs) are a family of proton-gated cation channels that contribute to a diverse array of functions including pain sensation, cell death during ischemia, and more broadly to neurotransmission in the central nervous system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c723441c0da90716aaceab7b399ecbe
https://doi.org/10.1080/19336950.2021.1976946
https://doi.org/10.1080/19336950.2021.1976946
Autor:
Bankston, Robert C Klipp
Acid-sensing ion channels (ASICs) are thought to be endogenous sensors of acidic pain in inflammatory pathways. It has previously been demonstrated that arachidonic acid (AA), a pain and inflammation promoting molecule, potentiates ASICs. However, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de9feee8c3c6cdf4d10122c127b4b022
https://doi.org/10.1101/2021.06.25.449979
https://doi.org/10.1101/2021.06.25.449979
Autor:
Robert C. Klipp, John Bankston
Publikováno v:
Biophysical Journal. 121:381a-382a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec7eb0b54d7d6bf306af1dacbfa15906
https://doi.org/10.1016/j.bpj.2021.11.836
https://doi.org/10.1016/j.bpj.2021.11.836
Autor:
Robert M. Strongin, Na Li, Jonathan J. Abramson, Robert C. Klipp, Xander H.T. Wehrens, Martha Sibrian-Vazquez, Qiongling Wang, Tarah A. Word
Publikováno v:
Heart Rhythm. 15:578-586
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an arrhythmogenic disorder caused by mutations in the cardiac ryanodine receptor RyR2 that increase diastolic calcium cation (Ca2+) leak from the sarcoplasmic reticulum (SR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5632a6bd047aaaa6aec3f48b06deff7c
https://doi.org/10.1016/j.hrthm.2017.12.017
https://doi.org/10.1016/j.hrthm.2017.12.017
Publikováno v:
The Journal of General Physiology
The integral membrane protein stomatin inhibits the gating of acid-sensing ion channels by an unknown mechanism. Klipp et al. suggest that stomatin binds to the C-terminus of ASIC3 and stabilizes the desensitized state via an interaction with the cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768edb042c1171097d8b32608dbbcbb8
Autor:
Robert C. Klipp, John R. Bankston
Publikováno v:
Biophysical Journal. 118:580a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2abba3986e0adc33672175dac0d26d0
https://doi.org/10.1016/j.bpj.2019.11.3147
https://doi.org/10.1016/j.bpj.2019.11.3147
Autor:
Robert C. Klipp, John R. Bankston
Publikováno v:
Biophysical Journal. 116:110a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37feee1f869964495112fac056ee919f
https://doi.org/10.1016/j.bpj.2018.11.625
https://doi.org/10.1016/j.bpj.2018.11.625