Zobrazeno 1 - 10
of 532
pro vyhledávání: '"Robert C. Kaplan"'
Autor:
Kai Luo, Alkis Taryn, Eun-Hye Moon, Brandilyn A. Peters, Scott D. Solomon, Martha L. Daviglus, Mayank M. Kansal, Bharat Thyagarajan, Marc D. Gellman, Jianwen Cai, Robert D. Burk, Rob Knight, Robert C. Kaplan, Susan Cheng, Carlos J. Rodriguez, Qibin Qi, Bing Yu
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Background Left ventricular diastolic dysfunction (LVDD) is an important precursor of heart failure (HF), but little is known about its relationship with gut dysbiosis and microbial-related metabolites. By leveraging the multi-omics data fro
Externí odkaz:
https://doaj.org/article/0605ae6bad3d410f866c056035d292cb
Autor:
Kai Luo, Brandilyn A. Peters, Jee-Young Moon, Xiaonan Xue, Zheng Wang, Mykhaylo Usyk, David B. Hanna, Alan L. Landay, Michael F. Schneider, Deborah Gustafson, Kathleen M. Weber, Audrey French, Anjali Sharma, Kathryn Anastos, Tao Wang, Todd Brown, Clary B. Clish, Robert C. Kaplan, Rob Knight, Robert D. Burk, Qibin Qi
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Gut dysbiosis has been linked with both HIV infection and diabetes, but its interplay with metabolic and inflammatory responses in diabetes, particularly in the context of HIV infection, remains unclear. Methods We first conducted
Externí odkaz:
https://doaj.org/article/ddd735eae386481991401f432e4d62a0
Autor:
Yasmin Mossavar-Rahmani, Juan Lin, Stephanie Pan, Rebecca J. Song, Xiaonan Xue, Nicole L. Spartano, Vanessa Xanthakis, Daniela Sotres-Alvarez, David X. Marquez, Martha Daviglus, Jordan A. Carlson, Humberto Parada, Kelly R. Evenson, Ana C. Talavera, Marc Gellman, Krista M. Perreira, Linda C. Gallo, Ramachandran S. Vasan, Robert C. Kaplan
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Physical activity promotes health and is particularly important during middle and older age for decreasing morbidity and mortality. We assessed the correlates of changes over time in moderate-to-vigorous physical activity (MVPA) i
Externí odkaz:
https://doaj.org/article/40e05441211a4c9b81c5dbc6ba037b4d
Autor:
Brandilyn A. Peters, Qibin Qi, Mykhaylo Usyk, Martha L. Daviglus, Jianwen Cai, Nora Franceschini, James P. Lash, Marc D. Gellman, Bing Yu, Eric Boerwinkle, Rob Knight, Robert D. Burk, Robert C. Kaplan
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTBackground The gut microbiome is altered in chronic kidney disease (CKD), potentially contributing to CKD progression and co-morbidities, but population-based studies of the gut microbiome across a wide range of kidney function and damage are
Externí odkaz:
https://doaj.org/article/6788ea50aa19424296eff1eb82380f3a
Autor:
Nuzulul Kurniansyah, Matthew O. Goodman, Alyna T. Khan, Jiongming Wang, Elena Feofanova, Joshua C. Bis, Kerri L. Wiggins, Jennifer E. Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J. Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L. Kinney, Jennifer A. Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, JoAnn E. Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C. Charles Gu, Donald M. Lloyd-Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M. Psaty, Donna K. Arnett, Carmen R. Isasi, Stephen S. Rich, Robert C. Kaplan, Susan Redline, Braxton D. Mitchell, Nora Franceschini, Daniel Levy, Jerome I. Rotter, Alanna C. Morrison, Tamar Sofer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population groups. We compare “clumping-and-thresholding” (PRSice2) and LD-based (LDPred2) methods to construct
Externí odkaz:
https://doaj.org/article/d721f599909e48e7aa862786e05f3dd9
Autor:
Zheng Wang, Brandilyn A. Peters, MacKenzie Bryant, David B. Hanna, Tara Schwartz, Tao Wang, Christopher C. Sollecito, Mykhaylo Usyk, Evan Grassi, Fanua Wiek, Lauren St. Peter, Wendy S. Post, Alan L. Landay, Howard N. Hodis, Kathleen M. Weber, Audrey French, Elizabeth T. Golub, Jason Lazar, Deborah Gustafson, Anjali Sharma, Kathryn Anastos, Clary B. Clish, Robert D. Burk, Robert C. Kaplan, Rob Knight, Qibin Qi
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background Alterations in gut microbiota have been implicated in HIV infection and cardiovascular disease. However, how gut microbial alterations relate to host inflammation and metabolite profiles, and their relationships with atheroscleros
Externí odkaz:
https://doaj.org/article/da80297957c64761a09224215e94a1c0
Autor:
Hongjiao Liu, Wodan Ling, Xing Hua, Jee-Young Moon, Jessica S. Williams-Nguyen, Xiang Zhan, Anna M. Plantinga, Ni Zhao, Angela Zhang, Rob Knight, Qibin Qi, Robert D. Burk, Robert C. Kaplan, Michael C. Wu
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Background Understanding human genetic influences on the gut microbiota helps elucidate the mechanisms by which genetics may influence health outcomes. Typical microbiome genome-wide association studies (GWAS) marginally assess the associati
Externí odkaz:
https://doaj.org/article/198f7a84d6c048ee9cd0fcb3451401e4
Autor:
Kyndaron Reinier, Jee‐Young Moon, Harpriya S. Chugh, Arayik Sargsyan, Kotoka Nakamura, Faye L. Norby, Audrey Uy‐Evanado, Gregory A. Talavera, Linda C. Gallo, Martha L. Daviglus, Katy Hadduck, Daniel Shepherd, Angelo Salvucci, Robert C. Kaplan, Sumeet S. Chugh
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 20 (2023)
Background Out‐of‐hospital sudden cardiac arrest (SCA) is a leading cause of mortality, making prevention of SCA a public health priority. No studies have evaluated predictors of SCA risk among Hispanic or Latino individuals in the United States.
Externí odkaz:
https://doaj.org/article/9581722b198340fbb184bfc774d34d8a
Autor:
Marsha M. Wheeler, Adrienne M. Stilp, Shuquan Rao, Bjarni V. Halldórsson, Doruk Beyter, Jia Wen, Anna V. Mihkaylova, Caitlin P. McHugh, John Lane, Min-Zhi Jiang, Laura M. Raffield, Goo Jun, Fritz J. Sedlazeck, Ginger Metcalf, Yao Yao, Joshua B. Bis, Nathalie Chami, Paul S. de Vries, Pinkal Desai, James S. Floyd, Yan Gao, Kai Kammers, Wonji Kim, Jee-Young Moon, Aakrosh Ratan, Lisa R. Yanek, Laura Almasy, Lewis C. Becker, John Blangero, Michael H. Cho, Joanne E. Curran, Myriam Fornage, Robert C. Kaplan, Joshua P. Lewis, Ruth J. F. Loos, Braxton D. Mitchell, Alanna C. Morrison, Michael Preuss, Bruce M. Psaty, Stephen S. Rich, Jerome I. Rotter, Hua Tang, Russell P. Tracy, Eric Boerwinkle, Goncalo R. Abecasis, Thomas W. Blackwell, Albert V. Smith, Andrew D. Johnson, Rasika A. Mathias, Deborah A. Nickerson, Matthew P. Conomos, Yun Li, Unnur Þorsteinsdóttir, Magnús K. Magnússon, Kari Stefansson, Nathan D. Pankratz, Daniel E. Bauer, Paul L. Auer, Alex P. Reiner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Most genetic association studies have been done on single nucleotide polymorphisms and small indels, while other types of variants have been less studied. Here, the authors use whole genome sequencing in a diverse population to identify and provide e
Externí odkaz:
https://doaj.org/article/a133b13c75514301b2ec8c00097b28db
Autor:
Ayana K. April-Sanders, Martha L. Daviglus, Un Jung Lee, Krista M. Perreira, Robert C. Kaplan, Michael J Blaha, Amber Pirzada, Aida L. Giachello, Aruni Bhatnagar, Rose Marie Robertson, Thanh-Huyen T. Vu, Carlos J. Rodriguez
Publikováno v:
American Journal of Medicine Open, Vol 9, Iss , Pp 100029- (2023)
Objective: To determine the prevalence and determinants of electronic nicotine delivery systems (ENDS) use among Hispanic/Latino adults from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Methods: Cross-sectional data collected betw
Externí odkaz:
https://doaj.org/article/0415e054bdb443a5ba96d627180d34ce