Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Robert C. Jones"'
Autor:
Fabio Zanini, Xibing Che, Nina E. Suresh, Carsten Knutsen, Paula Klavina, Yike Xie, Racquel Domingo-Gonzalez, Min Liu, Alexander Kum, Robert C. Jones, Stephen R. Quake, Cristina M. Alvira, David N. Cornfield
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Rapid expansion of the pulmonary microvasculature through angiogenesis drives alveolarization, the final stage of lung development that occurs postnatally and dramatically increases lung gas-exchange surface area. Disruption of pulmonary ang
Externí odkaz:
https://doaj.org/article/28e186d1c09b43ba95a13dc4cc7600e9
Autor:
Heidi K. Alleway, Tiffany J. Waters, Randall Brummett, Junning Cai, Ling Cao, Megan Reilly Cayten, Barry Antonio Costa‐Pierce, Yun‐Wei Dong, Steffen Cole Brandstrup Hansen, Shurong Liu, Qing Liu, Colin Shelley, Seth J. Theuerkauf, Lisa Tucker, Yue Wang, Robert C. Jones
Publikováno v:
Conservation Science and Practice, Vol 5, Iss 8, Pp n/a-n/a (2023)
Abstract The magnitude of negative environmental impacts generated by food production means it is now imperative we develop food systems in a way that can actively support the recovery of degraded ecosystems, while also meeting increasing demands for
Externí odkaz:
https://doaj.org/article/8104d6f333974fd889828656415b5fcf
Autor:
Fabio Zanini, Xibing Che, Carsten Knutsen, Min Liu, Nina E. Suresh, Racquel Domingo-Gonzalez, Steve H. Dou, Daoqin Zhang, Gloria S. Pryhuber, Robert C. Jones, Stephen R. Quake, David N. Cornfield, Cristina M. Alvira
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106097- (2023)
Summary: At birth, the lung is still immature, heightening susceptibility to injury but enhancing regenerative capacity. Angiogenesis drives postnatal lung development. Therefore, we profiled the transcriptional ontogeny and sensitivity to injury of
Externí odkaz:
https://doaj.org/article/b26cc1b660b54915931e23d68f0719cc
Autor:
Cristina Furlan, René A. M. Dirks, Peter C. Thomas, Robert C. Jones, Jing Wang, Mark Lynch, Hendrik Marks, Michiel Vermeulen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Affinity purification-mass spectrometry (AP-MS) can identify endogenous protein interactions but the need for high amounts of input material still limits its applicability. Here, the authors present a microfluidic-based AP-MS workflow that can captur
Externí odkaz:
https://doaj.org/article/b0ab23fc21264551ba1dea982ce9a0d1
Autor:
Felicia Reinitz, Elizabeth Y Chen, Benedetta Nicolis di Robilant, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
Publikováno v:
eLife, Vol 11 (2022)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease observed with aging that represents the most common form of dementia. To date, therapies targeting end-stage disease plaques, tangles, or inflammation have limited efficacy. Theref
Externí odkaz:
https://doaj.org/article/92c5abc287934048bbc8abb6eae7052f
Autor:
Ragini Phansalkar, Josephine Krieger, Mingming Zhao, Sai Saroja Kolluru, Robert C Jones, Stephen R Quake, Irving Weissman, Daniel Bernstein, Virginia D Winn, Gaetano D'Amato, Kristy Red-Horse
Publikováno v:
eLife, Vol 10 (2021)
Most cell fate trajectories during development follow a diverging, tree-like branching pattern, but the opposite can occur when distinct progenitors contribute to the same cell type. During this convergent differentiation, it is unknown if cells ‘r
Externí odkaz:
https://doaj.org/article/5b819ee9344840cb83dabc0bd4069398
Autor:
Colleen N McLaughlin, Maria Brbić, Qijing Xie, Tongchao Li, Felix Horns, Sai Saroja Kolluru, Justus M Kebschull, David Vacek, Anthony Xie, Jiefu Li, Robert C Jones, Jure Leskovec, Stephen R Quake, Liqun Luo, Hongjie Li
Publikováno v:
eLife, Vol 10 (2021)
Recognition of environmental cues is essential for the survival of all organisms. Transcriptional changes occur to enable the generation and function of the neural circuits underlying sensory perception. To gain insight into these changes, we generat
Externí odkaz:
https://doaj.org/article/74b6629249ee4630bde8783922a0e4bc
Autor:
Qijing Xie, Maria Brbic, Felix Horns, Sai Saroja Kolluru, Robert C Jones, Jiefu Li, Anay R Reddy, Anthony Xie, Sayeh Kohani, Zhuoran Li, Colleen N McLaughlin, Tongchao Li, Chuanyun Xu, David Vacek, David J Luginbuhl, Jure Leskovec, Stephen R Quake, Liqun Luo, Hongjie Li
Publikováno v:
eLife, Vol 10 (2021)
Neurons undergo substantial morphological and functional changes during development to form precise synaptic connections and acquire specific physiological properties. What are the underlying transcriptomic bases? Here, we obtained the single-cell tr
Externí odkaz:
https://doaj.org/article/52b08758320341fd9a60d8b91ca94a08
Autor:
Racquel Domingo-Gonzalez, Fabio Zanini, Xibing Che, Min Liu, Robert C Jones, Michael A Swift, Stephen R Quake, David N Cornfield, Cristina M Alvira
Publikováno v:
eLife, Vol 9 (2020)
At birth, the lungs rapidly transition from a pathogen-free, hypoxic environment to a pathogen-rich, rhythmically distended air-liquid interface. Although many studies have focused on the adult lung, the perinatal lung remains unexplored. Here, we pr
Externí odkaz:
https://doaj.org/article/7e460de9939643e49e63256515efae80
Autor:
Tzu-Chiao Lu, Maria Brbić, Ye-Jin Park, Tyler Jackson, Jiaye Chen, Sai Saroja Kolluru, Yanyan Qi, Nadja Sandra Katheder, Xiaoyu Tracy Cai, Seungjae Lee, Yen- Chung Chen, Niccole Auld, Chung-Yi Liang, Sophia H. Ding, Doug Welsch, Samuel D’Souza, Angela Oliveira Pisco, Robert C. Jones, Jure Leskovec, Eric C. Lai, Hugo J. Bellen, Liqun Luo, Heinrich Jasper, Stephen R. Quake, Hongjie Li
Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across the organism remain unclear. Here, we present the Aging Fly Cell Atlas, a single-nucleus transcriptomic map of the whole agingDrosophila.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af71a9446b3c4735eeefa4f24a01855d
https://doi.org/10.1101/2022.12.06.519355
https://doi.org/10.1101/2022.12.06.519355