Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Robert C. Glen"'
Autor:
Thomas L. Williams, Duuamene Nyimanu, Rhoda E. Kuc, Richard Foster, Robert C. Glen, Janet J. Maguire, Anthony P. Davenport
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Pulmonary arterial hypertension (PAH) is characterised by endothelial dysfunction and pathological vascular remodelling, resulting in the occlusion of pulmonary arteries and arterioles, right ventricular hypertrophy, and eventually fata
Externí odkaz:
https://doaj.org/article/96d17a331f9240c6a1914d929b042de1
Autor:
Lesley Hoyles, Matthew G. Pontifex, Ildefonso Rodriguez-Ramiro, M. Areeb Anis-Alavi, Khadija S. Jelane, Tom Snelling, Egle Solito, Sonia Fonseca, Ana L. Carvalho, Simon R. Carding, Michael Müller, Robert C. Glen, David Vauzour, Simon McArthur
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-21 (2021)
Abstract Background Communication between the gut microbiota and the brain is primarily mediated via soluble microbe-derived metabolites, but the details of this pathway remain poorly defined. Methylamines produced by microbial metabolism of dietary
Externí odkaz:
https://doaj.org/article/c0d2035498a04a8b9ff53c987c2ef532
Autor:
Thies Ingwersen, Christian Linnenberg, Emanuela D’Acunto, Shabnam Temori, Irene Paolucci, David Wasilewski, Behnam Mohammadi, Johannes Kirchmair, Robert C. Glen, Elena Miranda, Markus Glatzel, Giovanna Galliciotti
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a progressive neurodegenerative disease caused by point mutations in the gene for neuroserpin, a serine protease inhibitor of the nervous system. Different mutations are kn
Externí odkaz:
https://doaj.org/article/82d3602c215e4fa28f209ae781dcc486
Autor:
Cai Read, Duuamene Nyimanu, Peiran Yang, Rhoda E. Kuc, Thomas L. Williams, Christopher M. Fitzpatrick, Richard Foster, Robert C. Glen, Janet J. Maguire, Anthony P. Davenport
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Signaling through the apelin receptor is beneficial for a number of diseases including pulmonary arterial hypertension. The endogenous small peptides, apelin and elabela/toddler, are downregulated in pulmonary arterial hypertension but are not suitab
Externí odkaz:
https://doaj.org/article/2d0660c081eb47399d2ca55e2ed4196f
Autor:
Lesley Hoyles, Tom Snelling, Umm-Kulthum Umlai, Jeremy K. Nicholson, Simon R. Carding, Robert C. Glen, Simon McArthur
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Background Gut microbiota composition and function are symbiotically linked with host health and altered in metabolic, inflammatory and neurodegenerative disorders. Three recognised mechanisms exist by which the microbiome influences the gut
Externí odkaz:
https://doaj.org/article/394e2c9e178040eab3c66dcc6bc67dd5
Autor:
Sita N Shah, Tobias B-A Knausenberger, Emily Connell, Gwenaelle Le Gall, Tom A. J. Hardy, David W. Randall, Kieran McCafferty, Muhammad M. Yaqoob, E. Solito, Michael Müller, Andrew V. Stachulski, Robert C. Glen, David Vauzour, Lesley Hoyles, Simon McArthur
Chronic kidney disease is linked to impaired cognitive function and increased neurovascular disease risk even after correction for classical risk factors. The mechanism(s) underlying these links are unclear but may involve interactions of uraemic tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40e45f1a8ea1b95a090ac47a2e7bff3a
https://doi.org/10.1101/2022.11.12.516113
https://doi.org/10.1101/2022.11.12.516113
Autor:
Egle Solito, Michael Müller, Matthew G. Pontifex, Simon McArthur, Tom Snelling, Ana L. Carvalho, M. Areeb Anis-Alavi, Ildefonso Rodríguez-Ramiro, Sonia Fonseca, Lesley Hoyles, David Vauzour, Simon R. Carding, Khadija S. Jelane, Robert C. Glen
Publikováno v:
Microbiome
Microbiome, Vol 9, Iss 1, Pp 1-21 (2021)
Microbiome, Vol 9, Iss 1, Pp 1-21 (2021)
Background Communication between the gut microbiota and the brain is primarily mediated via soluble microbe-derived metabolites, but the details of this pathway remain poorly defined. Methylamines produced by microbial metabolism of dietary choline a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975de936c832374ca01444ae479f2a65
https://irep.ntu.ac.uk/id/eprint/44485/7/1480090_a1940_Hoyles.pdf
https://irep.ntu.ac.uk/id/eprint/44485/7/1480090_a1940_Hoyles.pdf
Publikováno v:
Metabolomics
Introduction Inductively coupled plasma mass spectrometry (ICP-MS) experiments generate complex multi-dimensional data sets that require specialist data analysis tools. Objective Here we describe tools to facilitate analysis of the ionome composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33fcc63f5e0d826505debde213918cb
https://www.repository.cam.ac.uk/handle/1810/329853
https://www.repository.cam.ac.uk/handle/1810/329853
Autor:
Thomas L Williams, David J. Huggins, Petra Sulentic, Janet J. Maguire, Robyn Macrae, Cai Read, Duuamene Nyimanu, Peiran Yang, Robert C. Glen, Anthony P. Davenport
Publikováno v:
Pharmacological Reviews
The predicted protein encoded by the APJ gene discovered in 1993 was originally classified as a class A G protein-coupled orphan receptor but was subsequently paired with a novel peptide ligand, apelin-36 in 1998. Substantial research identified a fa
Autor:
Sara Anjomani-Virmouni, Clare M. Isacke, Zoltan Takats, George Poulogiannis, Adamo Valle, Aurelien Tripp, A van Weverwijk, Paolo Inglese, Robert C. Glen, Nikolaos Koundouros, Evdoxia Karali, Jeremy K. Nicholson, R Filipe-Soares, G Elder
Publikováno v:
The Journal of Pathology. 248:S1-S23