Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Robert C. Getts"'
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1496 (2022)
3DNA holds promise as a carrier for drugs that can be intercalated into its core or linked to surface arms. Coupling 3DNA to an antibody targeting intercellular adhesion molecule 1 (ICAM-1) results in high lung-specific biodistributions in vivo. Whil
Externí odkaz:
https://doaj.org/article/dfc3a178d5a844d2847032fecb93661d
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 2, Pp n/a-n/a (2021)
Abstract Biodistribution studies are essential in drug carrier design and translation, and radiotracing provides a sensitive quantitation for this purpose. Yet, for biodegradable formulations, small amounts of free‐label signal may arise prior to o
Externí odkaz:
https://doaj.org/article/2a4a4d1b2a5648f9b3b88cead5a879eb
Publikováno v:
BioTechniques, Vol 44, Iss 6, Pp 815-818 (2008)
DNA dendrimers, conjugated with both anti-biotin antibodies and up to 350 labeling entities, were designed and adapted to protein microarray and enzyme-linked immunosorbent assay (ELISA) to improve the limits of protein detection with no additional s
Externí odkaz:
https://doaj.org/article/5e73e2a3b9774a288af34a3e2ce527de
Autor:
Johanna R. Mora, Robert C. Getts
Publikováno v:
BioTechniques, Vol 41, Iss 4, Pp 420-424 (2006)
Externí odkaz:
https://doaj.org/article/e2345f91bc0546eea20fc519a018cae3
Autor:
Janet A. Sawicki, Robert C. Getts, Jonathan R. Brody, Gregory E. Gonye, Masaya Jimbo, Neelanjan Mukherjee, Kelly Rhodes, Jacquelyn Gerhart, Narumi Furuuchi, Weidan Peng, Yu-Hung Huang
Growing evidence shows that cancer cells use mRNA-binding proteins and miRNAs to posttranscriptionally regulate signaling pathways to adapt to harsh tumor microenvironments. In ovarian cancer, cytoplasmic accumulation of mRNA-binding protein HuR (ELA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56789e52be814b2ce1f3f9f82b426db7
https://doi.org/10.1158/0008-5472.c.6508052.v1
https://doi.org/10.1158/0008-5472.c.6508052.v1
Autor:
Janet A. Sawicki, Robert C. Getts, Jonathan R. Brody, Gregory E. Gonye, Masaya Jimbo, Neelanjan Mukherjee, Kelly Rhodes, Jacquelyn Gerhart, Narumi Furuuchi, Weidan Peng, Yu-Hung Huang
Supplementary Fig. S2. A. HuR mRNA levels measured by RT-PCR in A2780 transiently-transfected with siHuR and siCtrl. B. Constitutively expressed shHuR maintains inhibition of HuR expression in ovarian tumor cells. Western blots of total cell lysates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2901d8fdd5f3861e0cac4328e2039c96
https://doi.org/10.1158/0008-5472.22410710
https://doi.org/10.1158/0008-5472.22410710
Autor:
Janet A. Sawicki, Robert C. Getts, Jonathan R. Brody, Gregory E. Gonye, Masaya Jimbo, Neelanjan Mukherjee, Kelly Rhodes, Jacquelyn Gerhart, Narumi Furuuchi, Weidan Peng, Yu-Hung Huang
Supplementary Table S1. Biological function of 5 up-regulated and 6 down-regulated genes having the highest fold differences in expression in response to HuR inhibition in A2780 cells. Shaded boxes indicate transcripts to which HuR binds directly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbf7ad65511c8490c8202a4cefd35bc
https://doi.org/10.1158/0008-5472.22410692
https://doi.org/10.1158/0008-5472.22410692
Autor:
Mayte Suárez-Fariñas, Hugh A. Sampson, Maria Suprun, Robert C. Getts, Rohit Raghunathan, George duToit, Gideon Lack, Henry T. Bahnson
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:835-842
Background In the LEAP (Learning Early About Peanut Allergy) trial, early consumption of peanut in high-risk infants was found to decrease the rate of peanut allergy at 5 years of age. Sequential epitope-specific (ses-)IgE is a promising biomarker of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccbcd822091839cd6b3213eac956f2a3
https://doi.org/10.1016/j.jaci.2021.01.030
https://doi.org/10.1016/j.jaci.2021.01.030
Autor:
Alex Porter, Stephen J. Galli, Kari C. Nadeau, Paul Kearney, Maria Suprun, Mayte Suárez-Fariñas, Clive Hayward, Galina Grishina, Marc Witmer, Hugh A. Sampson, Gideon Lack, Robert C. Getts, George Du Toit, Rebecca S. Chinthrajah, David Luta
Publikováno v:
Allergy. 76:3789-3797
Background Accurate diagnosis of peanut allergy is a significant clinical challenge. Here, a novel diagnostic blood test using the peanut bead-based epitope assay ("peanut BBEA") was developed utilizing the LEAP cohort and then validated using two in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5fef48135b833a2d713af48e3326a7
https://doi.org/10.1111/all.14905
https://doi.org/10.1111/all.14905
Autor:
Mayte Suárez-Fariñas, Helena L. Chang, Hugh A. Sampson, Kari C. Nadeau, Gustavo Gimenez, Maria Suprun, Robert C. Getts, Galina Grishina, Robert A. Wood
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: In a recent trial of milk oral immunotherapy (MOIT) with or without omalizumab in 55 patients with milk allergy treated for 28 months, 44 of 55 subjects passed a 10-g desensitization milk protein challenge; 23 of 55 subjects passed the 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed58e56322ce85eb913a91b02fe310dc
https://doi.org/10.1016/j.jaci.2018.10.028
https://doi.org/10.1016/j.jaci.2018.10.028