Zobrazeno 1 - 10
of 678
pro vyhledávání: '"Robert C. Elston"'
Autor:
Iain A. Gillespie, Eleanor Barnes, Ian C. K. Wong, Philippa C. Matthews, Graham S. Cooke, Craig Tipple, Robert C. Elston, Yunhao Liu, David A. Smith, Tingyan Wang, Jim Davies, Kinga A. Várnai, Oliver Freeman, Kenneth K. C. Man, Wallis C. Y. Lau, Ben Glampson, Xing Meng, Eleonora Morais, Sen Liu, Luca Mercuri, Naomi Boxall, Sarah Jenner, Stuart Kendrick, Jane Dong, Dickens Theodore
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 11, Pp 2513-2532 (2023)
Abstract Introduction Chronic hepatitis B virus (HBV) infection is associated with significant global morbidity and mortality. Low treatment rates are observed in patients living with HBV; the reasons for this are unclear. This study sought to descri
Externí odkaz:
https://doaj.org/article/07d54f87960d448e9f684c59b8715e9c
Autor:
Iain A. Gillespie, Eleanor Barnes, Ian C. K. Wong, Philippa C. Matthews, Graham S. Cooke, Craig Tipple, Robert C. Elston, Yunhao Liu, David A. Smith, Tingyan Wang, Jim Davies, Kinga A. Várnai, Oliver Freeman, Kenneth K. C. Man, Wallis C. Y. Lau, Ben Glampson, Xing Meng, Eleonora Morais, Sen Liu, Luca Mercuri, Naomi Boxall, Sarah Jenner, Stuart Kendrick, Jane Dong, Dickens Theodore
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 11, Pp 2533-2534 (2023)
Externí odkaz:
https://doaj.org/article/0b5399613fa9482087b0a6c07546eb13
Autor:
Bengt Zöller, MirNabi Pirouzifard, Peter J. Svensson, Björn Holmquist, Emelie Stenman, Robert C. Elston, Yeunjoo E. Song, Jan Sundquist, Kristina Sundquist
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 24 (2021)
Background This is the first nationwide segregation analysis that aimed to determine whether familial venous thromboembolism (VTE) is attributable to inheritance and/or shared environment, and the possible mode of inheritance. Methods and Results The
Externí odkaz:
https://doaj.org/article/a62e5963954440f6af803071b27ced0e
Autor:
Meiling Liu, Sanghoon Moon, Longfei Wang, Sulgi Kim, Yeon-Jung Kim, Mi Yeong Hwang, Young Jin Kim, Robert C. Elston, Bong-Jo Kim, Sungho Won
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Copy number variation (CNV) is known to play an important role in the genetics of complex diseases and several methods have been proposed to detect association of CNV with phenotypes of interest. Statistical methods for CNV associ
Externí odkaz:
https://doaj.org/article/47edb9babd434a258777f818dbbfcf9d
Autor:
Rong Yang, Lin Li, Sara Bretschger Seidelmann, Gong-Qing Shen, Sonia Sharma, Shaoqi Rao, Kalil G. Abdullah, Kenneth G. MacKinlay, Robert C. Elston, Qiuyun Chen, Eric J. Topol, Qing Kenneth Wang
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1442-1451 (2010)
Plasma HDL cholesterol levels (HDL-C) are an independent predictor of coronary artery disease (CAD). We have completed a genome-wide linkage scan for HDL-C in a US cohort consisting of 388 multiplex families with premature CAD (GeneQuest). The herita
Externí odkaz:
https://doaj.org/article/48a701ef30c84160a9ea692485c2ada9
Autor:
Amitabh Chak, Wendy Brock, James M. Warfe, Apoorva Chandar, Sanford D. Markowitz, Kishore Guda, Joseph E. Willis, Ye D. Tian, Julian A. Abrams, Prasad G. Iyer, Jean S. Wang, Nicholas J. Shaheen, Marcia Canto, Sumeet K. Mittal, Ashley Faulx, William M. Grady, Gary W. Falk, Jill S. Barnholtz-Sloan, Robert C. Elston, Xiangqing Sun
The relationship of age and date of birth (DOB) in the data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2af4ff4335ced3302a7244aa0e00f7
https://doi.org/10.1158/1055-9965.22436986
https://doi.org/10.1158/1055-9965.22436986
Autor:
Amitabh Chak, Wendy Brock, James M. Warfe, Apoorva Chandar, Sanford D. Markowitz, Kishore Guda, Joseph E. Willis, Ye D. Tian, Julian A. Abrams, Prasad G. Iyer, Jean S. Wang, Nicholas J. Shaheen, Marcia Canto, Sumeet K. Mittal, Ashley Faulx, William M. Grady, Gary W. Falk, Jill S. Barnholtz-Sloan, Robert C. Elston, Xiangqing Sun
Background: Barrett's esophagus is often asymptomatic and only a small portion of Barrett's esophagus patients are currently diagnosed and under surveillance. Therefore, it is important to develop risk prediction models to identify high-risk individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df4d0267e7d35a9b5d6ea39baedca80
https://doi.org/10.1158/1055-9965.c.6515653.v1
https://doi.org/10.1158/1055-9965.c.6515653.v1
Autor:
Robert C. Elston, Lara Sucheston-Campbell, Lina Jandorf, Deborah O. Erwin, Jill Barnholtz-Sloan, Yanwen Chen, Xiangqing Sun, Heather M. Ochs-Balcom
Supplementary Figure 4. Model-free multi-point linkage by RELPAL with a maximum of 1,000,000 permutations using all relative pairs, adjusting for age and global ancestry at the individual level. Linkage P values evaluated using the alternative varian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7b1ab44d072c2c92b97f9733017f95
https://doi.org/10.1158/1055-9965.22437547.v1
https://doi.org/10.1158/1055-9965.22437547.v1
Autor:
Amitabh Chak, Wendy Brock, James M. Warfe, Apoorva Chandar, Sanford D. Markowitz, Kishore Guda, Joseph E. Willis, Ye D. Tian, Julian A. Abrams, Prasad G. Iyer, Jean S. Wang, Nicholas J. Shaheen, Marcia Canto, Sumeet K. Mittal, Ashley Faulx, William M. Grady, Gary W. Falk, Jill S. Barnholtz-Sloan, Robert C. Elston, Xiangqing Sun
Supplementary Methods of imputation of age and estimating the parameters of the prediction model. Supplementary Table S1 Missing rates on the 8 covariates in the training and validation datasets. Supplementary Table S2 Stepwise removal of covariates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b15ab366ce0b096006f957299e55ab1
https://doi.org/10.1158/1055-9965.22436974.v1
https://doi.org/10.1158/1055-9965.22436974.v1
Autor:
Robert C. Elston, Lara Sucheston-Campbell, Lina Jandorf, Deborah O. Erwin, Jill Barnholtz-Sloan, Yanwen Chen, Xiangqing Sun, Heather M. Ochs-Balcom
Supplementary Figure 3. Genome-wide model-free multi-point linkage by SIBPAL, P-values based on up to 1,000,000 permutations (Haseman-Elston regression), with DOB (sibpair sum and difference) and global ancestry (sibpair difference) as covariates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59209e99c079c76674d113bf4ea27e40
https://doi.org/10.1158/1055-9965.22437550
https://doi.org/10.1158/1055-9965.22437550