Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Robert C. Roach"'
Autor:
Nicolas Bourdillon, Sasan Yazdani, Jean-Marc Vesin, Andrew W. Subudhi, Andrew T. Lovering, Robert C. Roach, Bengt Kayser
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
IntroductionBaroreflex sensitivity (BRS) is essential to ensure rapid adjustment to variations in blood pressure (BP). Spontaneous baroreflex function can be assessed using continuous recordings of blood pressure. The goal of this study was to compar
Externí odkaz:
https://doaj.org/article/4a497c45c7fd4bf7b12ca50143b3be12
Autor:
Anren Song, Yujin Zhang, Leng Han, Gennady G. Yegutkin, Hong Liu, Kaiqi Sun, Angelo D’Alessandro, Jessica Li, Harry Karmouty-Quintana, Takayuki Iriyama, Tingting Weng, Shushan Zhao, Wei Wang, Hongyu Wu, Travis Nemkov, Andrew W. Subudhi, Sonja Jameson-Van Houten, Colleen G. Julian, Andrew T. Lovering, Kirk C. Hansen, Hong Zhang, Mikhail Bogdanov, William Dowhan, Jianping Jin, Rodney E. Kellems, Holger K. Eltzschig, Michael Blackburn, Robert C. Roach, Yang Xia
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Humans that reach high altitude soon after the first ascent show faster adaptation to hypoxia. Songet al. show that this adaptive response relies on decreased red blood cell uptake of plasma adenosine due to reduced levels of nucleoside transporter E
Externí odkaz:
https://doaj.org/article/ab90ef4532bf424aa26dc070a2adc9be
Autor:
Kaiqi Sun, Yujin Zhang, Angelo D’Alessandro, Travis Nemkov, Anren Song, Hongyu Wu, Hong Liu, Morayo Adebiyi, Aji Huang, Yuan E. Wen, Mikhail V. Bogdanov, Alejandro Vila, John O’Brien, Rodney E. Kellems, William Dowhan, Andrew W. Subudhi, Sonja Jameson-Van Houten, Colleen G. Julian, Andrew T. Lovering, Martin Safo, Kirk C. Hansen, Robert C. Roach, Yang Xia
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The presence of the signalling lipid Sphingosine 1-phosphate (S1P) in erythrocytes has unclear physiological implications. Here the authors show that the S1P-generating enzyme Sphingosine kinase type 1 and its product S1P play an important role in th
Externí odkaz:
https://doaj.org/article/39c2f9d37bab46039537980e86d2c562
Autor:
Nicolas Bourdillon, Sasan Yazdani, Andrew W. Subudhi, Andrew T. Lovering, Robert C. Roach, Jean-Marc Vesin, Bengt Kayser
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: Baroreflex sensitivity (BRS) is essential to ensure rapid adjustment to variations in blood pressure (BP). Little is known concerning the adaptive responses of BRS during acclimatization to high altitude at rest and during exercise.Meth
Externí odkaz:
https://doaj.org/article/805b7b9b9f5c443c93740bde35956430
Autor:
Travis Nemkov, Kaiqi Sun, Julie A. Reisz, Anren Song, Tatsuro Yoshida, Andrew Dunham, Matthew J. Wither, Richard O. Francis, Robert C. Roach, Monika Dzieciatkowska, Stephen C. Rogers, Allan Doctor, Anastasios Kriebardis, Marianna Antonelou, Issidora Papassideri, Carolyn T. Young, Tiffany A. Thomas, Kirk C. Hansen, Steven L. Spitalnik, Yang Xia, James C. Zimring, Eldad A. Hod, Angelo D’Alessandro
Publikováno v:
Haematologica, Vol 103, Iss 2 (2018)
Hypoxanthine catabolism in vivo is potentially dangerous as it fuels production of urate and, most importantly, hydrogen peroxide. However, it is unclear whether accumulation of intracellular and supernatant hypoxanthine in stored red blood cell unit
Externí odkaz:
https://doaj.org/article/383f9de361b74e8a85e1f353c5c2cad1
Autor:
Jui-Lin eFan, Andrew W Subudhi, James eDuffin, Andrew T Lovering, Robert C Roach, Bengt eKayser
Publikováno v:
Frontiers in Physiology, Vol 6 (2016)
Previous studies reported enhanced cerebrovascular CO2 reactivity upon ascent to high altitude using linear models. However, there is evidence that this response may be sigmoidal in nature. Moreover, it was speculated that these changes at high altit
Externí odkaz:
https://doaj.org/article/75abde482fe249a2878c125a580e3751
Autor:
Kaitlyn G. DiMarco, Kara M. Beasley, Karina Shah, Julia P. Speros, Jonathan E. Elliott, Steven S. Laurie, Joseph W. Duke, Randall D. Goodman, Joel Eben Futral, Jerold A. Hawn, Robert C. Roach, Andrew T. Lovering
Publikováno v:
Experimental physiologyREFERENCES. 107(2)
What is the central question to this study? Is there a relationship between a patent foramen ovale and the development of acute mountain sickness and an exaggerated increase in pulmonary pressure in response to 7-10 h of normobaric hypoxia? What is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29754eda0cc04af9b2583222ab33062
https://pubmed.ncbi.nlm.nih.gov/34907608
https://pubmed.ncbi.nlm.nih.gov/34907608
Autor:
Benjamin J Ryan, Nadine B Wachsmuth, Walter F Schmidt, William C Byrnes, Colleen G Julian, Andrew T Lovering, Andrew W Subudhi, Robert C Roach
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108788 (2014)
It is classically thought that increases in hemoglobin mass (Hbmass) take several weeks to develop upon ascent to high altitude and are lost gradually following descent. However, the early time course of these erythropoietic adaptations has not been
Externí odkaz:
https://doaj.org/article/90e889f7762f4134a3bff40e0bd5de15
Autor:
Andrew W Subudhi, Nicolas Bourdillon, Jenna Bucher, Christopher Davis, Jonathan E Elliott, Morgan Eutermoster, Oghenero Evero, Jui-Lin Fan, Sonja Jameson-Van Houten, Colleen G Julian, Jonathan Kark, Sherri Kark, Bengt Kayser, Julia P Kern, See Eun Kim, Corinna Lathan, Steven S Laurie, Andrew T Lovering, Ryan Paterson, David M Polaner, Benjamin J Ryan, James L Spira, Jack W Tsao, Nadine B Wachsmuth, Robert C Roach
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92191 (2014)
An understanding of human responses to hypoxia is important for the health of millions of people worldwide who visit, live, or work in the hypoxic environment encountered at high altitudes. In spite of dozens of studies over the last 100 years, the b
Externí odkaz:
https://doaj.org/article/c923b4453ad34a8982e035a8ee50a6a2
Autor:
Mollie Scanagatta‐Long, Steven S. Laurie, Andrew T. Lovering, Trevor A. Day, Jonathan E. Elliott, Robert C. Roach, Donna Zehner, Randall D. Goodman, Jerold A. Hawn, Eben Futral
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba403e687990f9ecbe3f01873d6b9488
https://doi.org/10.1096/fasebj.2021.35.s1.04586
https://doi.org/10.1096/fasebj.2021.35.s1.04586