Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Robert C Piper"'
Autor:
Natalya Pashkova, Lokesh Gakhar, Liping Yu, Nicholas J Schnicker, Annabel Y Minard, Stanley Winistorfer, Ivan E Johnson, Robert C Piper
Publikováno v:
eLife, Vol 10 (2021)
Attachment of ubiquitin (Ub) to cell surface proteins serves as a signal for internalization via clathrin-mediated endocytosis (CME). How ubiquitinated membrane proteins engage the internalization apparatus remains unclear. The internalization appara
Externí odkaz:
https://doaj.org/article/8261cc559c5b4ab88fd1e6fa0e9ec498
Autor:
Peng Xu, Hannah M Hankins, Chris MacDonald, Samuel J Erlinger, Meredith N Frazier, Nicholas S Diab, Robert C Piper, Lauren P Jackson, Jason A MacGurn, Todd R Graham
Publikováno v:
eLife, Vol 6 (2017)
The COPI coat forms transport vesicles from the Golgi complex and plays a poorly defined role in endocytic trafficking. Here we show that COPI binds K63-linked polyubiquitin and this interaction is crucial for trafficking of a ubiquitinated yeast SNA
Externí odkaz:
https://doaj.org/article/e86d0fb2b2b3432b834acaa7444ecda2
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104017 (2014)
The Caspase Recruitment Domain (CARD) from the innate immune receptor NOD1 was crystallized with Ubiquitin (Ub). NOD1 CARD was present as a helix-swapped homodimer similar to other structures of NOD1 CARD, and Ub monomers formed a homodimer similar i
Externí odkaz:
https://doaj.org/article/91780476fdd04f74865170b068ff9c29
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/e1e98ca527de421b83ba51f37d17256b
Autor:
David A. Ruhl, Ewa Bomba-Warczak, Emma T. Watson, Mazdak M. Bradberry, Tabitha A. Peterson, Trina Basu, Alyssa Frelka, Chantell S. Evans, Joseph S. Briguglio, Tamara Basta, Michael H. B. Stowell, Jeffrey N. Savas, Avtar Roopra, Robert A. Pearce, Robert C. Piper, Edwin R. Chapman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The functional role of synaptotagmin-17 (syt-17) has remained unanswered. In this study, authors demonstrate that syt-17 exists in two distinct pools in hippocampal neurons (Golgi complex and early endosomes), where it served two completely independe
Externí odkaz:
https://doaj.org/article/2285b841eadf401cae3e662ea7ba2f42
Publikováno v:
Kidney360. 4:162-176
Autor:
Christopher P. Ptak, Tabitha A. Peterson, Jesse B. Hopkins, Christopher A. Ahern, Michael E. Shy, Robert C. Piper
Mutations in Myelin Protein Zero (MPZ) account for 5% of Charcot-Marie-Tooth cases and can cause demyelinating or axonal phenotypes, reflecting the diverse roles of MPZ in Schwann cells. MPZ holds the apposing membranes of the myelin sheath together,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52ea1c55e4a10e4fdf90d568145b698
https://doi.org/10.1101/2023.03.18.533291
https://doi.org/10.1101/2023.03.18.533291
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db603490832812e2263955b9cf1ba41b
https://doi.org/10.1016/b978-0-12-821618-7.00025-0
https://doi.org/10.1016/b978-0-12-821618-7.00025-0
Autor:
Brian A. Davies, Johanna A. Payne, Cole P. Martin, Destiny Schultz, Bennett G. Childs, Cheng Zhang, Karthik Jeganathan, Ines Sturmlechner, Thomas A. White, Alain de Bruin, Huiqin Chen, Michael A. Davies, Sarah Jachim, Nathan K. LeBrasseur, Robert C. Piper, Hu Li, Darren J. Baker, Jan van Deursen, David J. Katzmann
Endosomal Sorting Complexes Required for Transport (ESCRTs) drive reverse topology membrane remodeling events including the formation of intralumenal vesicles within multivesicular bodies, the budding of retroviruses from the plasma membrane, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cb5c3cb386817736dfe03b4a5f056e3
https://doi.org/10.1101/2022.08.02.502401
https://doi.org/10.1101/2022.08.02.502401
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 44(8)
The Endosomal Sorting Complexes Required for Transport (ESCRTs) drive membrane remodeling in a variety of cellular processes that include the formation of endosomal intralumenal vesicles (ILVs) during multivesicular body (MVB) biogenesis. During MVB