Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Robert C M Stephens"'
Publikováno v:
International Journal of Environmental Research and Public Health. 20:4678
Background: The use of exercise testing has expanded in recent decades and there is a wealth of information examining the prognostic significance of exercise variables, such as peak oxygen consumption or ventilatory measures whilst exercising. Howeve
Autor:
Anna Reyes, Tom E.F. Abbott, Brian H. Cuthbertson, Shaun M. May, Rupert M Pearse, Gladys Martir, Gareth L. Ackland, Ana Gutierrez del Arroyo, Duminda N. Wijeysundera, Robert C M Stephens, David Brealey
Publikováno v:
Br J Anaesth
BACKGROUND: Elevated plasma or serum troponin, indicating perioperative myocardial injury (PMI), is common after noncardiac surgery. However, underlying mechanisms remain unclear. Acute coronary syndrome (ACS) is associated with the early appearance
Autor:
Ana Gutierrez del Arroyo, Tom E.F. Abbott, David Brealey, Duminda N. Wijeysundera, Robert C M Stephens, Brian H. Cuthbertson, Shaun M. May, Gladys Martir, Rupert M Pearse, Gareth L. Ackland, Anna Reyes
BackgroundElevated plasma/serum troponin, indicating perioperative myocardial injury (PMI), is common after non-cardiac surgery. However, underlying mechanisms remain unclear. Acute coronary syndrome (ACS) is associated with the early appearance of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6a30c105eda1600d8633d756a6421b
https://doi.org/10.1101/2020.02.24.20027383
https://doi.org/10.1101/2020.02.24.20027383
Autor:
Harindra C. Wijeysundera, Marcin Wasowicz, M. Ellis, S. Pitt, Robert C M Stephens, Ethel Black, N. McMillan, B. Riedel, J. Tai, Manuel Pinto, Lisa Loughney, C. Wilde, D. Bramley, H. Thompson, H. Lawrence, Y. Kirabiyik, E. Smith, C. Bolger, Usha Gurunathan, N. Tantony, Hannah Collins, Timothy G. Short, A. Raj, Thais Creary, N. Ami, B. Borg, S. Gabriel, A.M. Southcott, S. Yagnik, D. Campbell, A. Hunt, Chang Joon Kim, Paul Oh, T. Ahmad, Sarah James, C. Crescini, K. Hagen, J. Malherbe, M. Lorimer, R. Raobaikady, D. Mcallister, R. Jang, Annette Dent, L. Day, Philip Masel, Helder Filipe, W.S. Beattie, J.K. Higgie, Thomas Painter, M. Gertsman, Angela Jerath, H. Sivakumar, Christopher X. Wong, A. Jason-Smith, M. Stanbrook, Marta Januszewska, L. Lee, Keyvan Karkouti, Phoebe Bodger, G. Back, P. Sivalingam, Michael H-G. Li, Andrew Macalister Hall, Hugh Taylor, J. Douglas, Helen Houston, K. Steele, R. Belliard, Kirsty Everingham, Ellen Waymouth, Shelly Au, S. Macklin, C.H. Angus Lee, E. Wright, Bruce Thompson, A. Bodger, Jeffrey J. Pretto, Mark J. Edwards, Edyta Niebrzegowska, J. Whalley, Fiona H. Marshall, M. Lum, S. Allen, Mandeep-Kaur Phull, C.D. Mazer, Christopher A. Stonell, Daniel Martin, K. Brunello, John J McNeil, Sandy Jack, Neil MacDonald, A. Gutierrez del Arroyo, S. Bates, Richard Brull, Graham S Hillis, A. Kennedy, J. Kunasingam, J. Pazmino-Canizares, Hilmy Ismail, Karen Salmon, M. Towns, L. Andrews, Gareth L. Ackland, M. Melo, A. Murmane, Kwok M. Ho, Karen Dobson, K. Pirie, R. Miller, J. Samuels, Richard Haslop, J. Brannan, J. Kumar, R Kerridge, Michael Celinski, S. Wallace, John Grant, P. Dalley, Leanne Seaward, Colin J L McCartney, Christian M. Beilstein, Stuart A. McCluskey, J. Van Der Westhuizen, Shaman Jhanji, S. Kynaston, Kate Leslie, L. Gallego-Paredes, J. Dimech, R. Lifford, M.G. Godsall, Vincent W. S. Chan, Andrew M. Brown, L. Navarra, Ying Hu, Marlynn Ali, M. Koutra, Brian H. Cuthbertson, N Terblanche, Stephen Choi, Helen A. Lindsay, M. Abolfathi, Hance Clarke, Bryony Tyrell, Duminda N. Wijeysundera, A.M. Carrera, Martin Rooms, R. Sara, Oystein Tronstad, P. Somascanthan, H. Ismail, K. Greaves, S. Olliff, A. MacCormick, A. Collingwood, Adrian D. Elliott, M. Pakats, Muhammad Mamdani, K. Kenchington, C. Corriea, Denny Z. H. Levett, K. Flores, S. Hurford, Anmol Yagnik, A. Tippett, Bernhard Riedel, Anna Reyes, A. Melville, N. Beauchamp, Kim Golder
Publikováno v:
British journal of anaesthesia. 126(1)
Background Accurate assessment of functional capacity, a predictor of postoperative morbidity and mortality, is essential to improving surgical planning and outcomes. We assessed if all 12 items of the Duke Activity Status Index (DASI) were equally i
Autor:
Gary Minto, Gareth L. Ackland, Thomas Owen, Robert C M Stephens, Pradeep Prabhu, Ana Gutierrez del Arroyo, Martin Clark, John Whittle
Publikováno v:
Brain, Behavior, and Immunity. 67:47-53
Objective Experimental animal models demonstrate that autonomic activity regulates systemic inflammation. By contrast, human studies are limited in number and exclusively use heart rate variability (HRV) as an index of cardiac autonomic regulation. H
Autor:
Gary Minto, Richard Green, Ana Gutierrez del Arroyo, Pradeep Pradhu, Claire West, Tom E.F. Abbott, Alexandra Williams, Martin Clark, Abigail Patrick, G. Minto, Claire Williams, Thomas Owen, Shamir Karmali, Claire Pollak, Emma Vickers, Anna Lach, Andrew J. Toner, John Whittle, G.L. Ackland, Rupert M Pearse, James M. Otto, Laura Montague, Gareth L. Ackland, Laura Gallego Paredes, Angela King, Daniel Hull, Robert C M Stephens, Amy Jones, J. Whittle
Publikováno v:
British Journal of Anaesthesia. 120:94-100
Systemic arterial pulse pressure (systolic minus diastolic pressure) ≤53 mm Hg in patients with cardiac failure is correlated with reduced stroke volume and is independently associated with accelerated morbidity and mortality. Given that deconditio
Autor:
Shaun M. May, Gareth L. Ackland, Gladys Martir, Shamir Karmali, Anna Reyes, Robert C M Stephens, David Brealey, Joseph Reynolds
Publikováno v:
British Journal of Anaesthesia. 123:e509-e510
Autor:
Laura Gallego Paredes, Joseph Reynolds, Robert C M Stephens, Gareth L. Ackland, Shaun M. May, David Brealey, Gladys Martir, Anna Reyes, Shamir Karmali
BackgroundMyocardial injury is more frequent after non-cardiac surgery in patients with preoperative cardiac vagal dysfunction as quantified by delayed heart rate recovery after cessation of cardiopulmonary exercise testing. Here, we hypothesised tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeeb5f66ca5c92b25ee587f87845d0e0
https://doi.org/10.1101/623165
https://doi.org/10.1101/623165
Autor:
Alexander J. Fowler, E. Niebrzegowska, Anna Reyes, Gareth L. Ackland, A.W. Khan, R.A. Archbold, Shamir Karmali, A. Gutierrez del Arroyo, Tom E.F. Abbott, Robert C M Stephens, Pervez Sultan, L. Gallego Paredes, S. Woldman, John Whittle, David Cain, Andrew Wragg, Elisa Kam, Mark R Edwards, N.J. MacDonald, Rupert M Pearse, T. Ahmad
Publikováno v:
British journal of anaesthesia. 122(2)
Background Systemic inflammation is pivotal in the pathogenesis of cardiovascular disease. As inflammation can directly cause cardiomyocyte injury, we hypothesised that established systemic inflammation, as reflected by elevated preoperative neutroph
Autor:
Tom E.F. Abbott, Johan Malherbe, Hannah Collins, Chang Joon Kim, Michelle Gertsman, Charmagne Crescini, Andrew MacCormick, Brigette Borg, J. Tai, Miriam Towns, Rene Belliard, Althea Ambosta, Rupert M Pearse, Mandeep Phull, H. Lawrence, Martin Rooms, Denny Z. H. Levett, Sandra Allen, Stuart A. McCluskey, Maria Koutra, Shaman Jhanji, Mathew Ellis, Fiona H. Marshall, Kevin E. Thorpe, Sally Hurford, Anna Tippett, Colin J. L. McCartney, Adrian Hall, Gareth L. Ackland, Paul Oh, K. Pirie, T. Ahmad, Harindra C. Wijeysundera, R Kerridge, Miriam Abolfathi, J. Douglas, Rhiannon Lifford, Simon Macklin, C. David Mazer, Edyta Niebrzegowska, Alanna Bodger, Magda Melo, J. Whalley, Marta Januszewska, Julian Dimech, Pheobe Bodger, Alistair Brown, Ann Kennedy, Douglas M Campbell, S. Olliff, Angela Jerath, Anna Maria Carrera, Anmol Yagnik, Bernhard Riedel, Andrew Murmane, Philip Masel, Manuel Pinto, Sanjay Yagnik, N Terblanche, Paul S. Myles, Leanlove Navarra, Sophie Wallace, W. Scott Beattie, Robert C M Stephens, Pal Sivalingam, Helder Filipe, Thais Creary, Geraldine Back, Guy Godsall, Natasha Tantony, Stephen Choi, Ellen Waymouth, Kirsty Everingham, Adrian D. Elliott, Chris Wilde, Sandy Jack, Natalie McMillan, Katherine Steele, Mark A Shulman, Mark J. Edwards, Helen Houston, Vincent W. S. Chan, Catherine Farrington, Lauren Day, Kushlin Higgie, Hugh Taylor, Shelly Au, John Brannan, Clare Bolger, Bruce Thompson, Andrew Melville, John Grant, Katherine Hagen, Paul Dalley, Daniel Martin, Reuben Miller, Muhammad Mamdani, Hilmy Ismail, Harry Sivakumar, Karen Salmon, N. Ami, Joanne Samuel, Graham S. Hillis, D. Bramley, H. Thompson, Ravishanar Raobaikady, Michael Lorimer, Andrew Collingwood, Yesim Kirabiyik, Michael Celinski, Ewan Wright, Usha Gurunathan, R. Sara, Carmen Corriea, Sharon Gabriel, Emma Smith, Lynn Andrews, Janarthanee Kunasingam, Ryan Jang, Kim Golder, Hance Clarke, Laura Gallego-Paredes, Kate Leslie, Jane McNeil, Thomas Painter, Timothy G. Short, Mari Liis Pakats, Brian H. Cuthbertson, Adelaide Jason-Smith, Bryony Tyrell, K. Flores, D. Mcallister, Samantha Bates, Anna Reyes, Helen A. Lindsay, Jonathan Kumar, John Granton, Richard Brull, Nicola Beauchamp, Marcin Wasowicz, Duminda N. Wijeysundera, Leanne Seaward, Kate Brunello, Mark Lum, Jeffrey J. Pretto, Lisa Loughney, Ethel Black, Ying Hu, Simon Pitt, Chris Stonell, Marlynn Ali, Ashok Raj, Kay Kenchington, Matthew Stanbrook, Michael P.W. Grocott, Annette Dent, Anna Hunt, Sarah James, A.M. Southcott, Joreline Van Der Westhuizen, Keyvan Karkouti, Ana Gutierrez del Arroyo, J. Pazmino-Canizares, N Macdonald, Leanna Lee, Richard Haslop, K. Greaves, Stephen Kynaston, Bernard L. Croal, Elizabeth B. Torres, Karen Dobson, Christian M. Beilstein, Christopher X. Wong, Oystein Tronstad, P. Somascanthan
Publikováno v:
Lancet (London, England). 391(10140)
Summary Background Functional capacity is an important component of risk assessment for major surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain accuracy. We did a study to compare preoperative subjective