Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robert C Hoy"'
Autor:
Devorah M Natelson, Alon Lai, Divya Krishnamoorthy, Robert C Hoy, James C Iatridis, Svenja Illien-Jünger
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0227527 (2020)
Type 2 diabetes and obesity are associated with back pain in juveniles and adults and are implicated in intervertebral disc (IVD) degeneration. Hypercaloric Western diets are associated with both obesity and type 2 diabetes. The objective of this stu
Externí odkaz:
https://doaj.org/article/96d5e4c409cb45338ed2d60d9828eb94
Autor:
Vagner Oliveira Carvalho Rigaud, Robert C. Hoy, Justin Kurian, Clare Zarka, Michael Behanan, Isabella Brosious, Jennifer Pennise, Tej Patel, Tao Wang, Jaslyn Johnson, Lindsay M. Kraus, Sadia Mohsin, Steven R. Houser, Mohsin Khan
Publikováno v:
Circulation. 147:324-337
Background: Developmental cardiac tissue holds remarkable capacity to regenerate after injury and consists of regenerative mononuclear diploid cardiomyocytes. On maturation, mononuclear diploid cardiomyocytes become binucleated or polyploid and exit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5470f1e2a258bc9819abc515ee8d128
https://doi.org/10.1161/circulationaha.122.059346
https://doi.org/10.1161/circulationaha.122.059346
Autor:
Lindsay Kraus, Lena Ma, Yijun Yang, Faustina Nguyen, Robert C. Hoy, Tomoko Okuno, Mohsin Khan, Sadia Mohsin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The adult heart following injury such as a myocardial infarction forms a fibrotic scar associated with transformation of resident cardiac fibroblasts into myofibroblast, accelerating cardiac remodeling and dysfunction. Cell therapies provide a novel
Externí odkaz:
https://doaj.org/article/519d550cf9f34b6195ecc9ce36ca851a
Autor:
Divya Krishnamoorthy, Robert C. Hoy, Devorah M. Natelson, Olivia M. Torre, Damien M. Laudier, James C. Iatridis, Svenja Illien-Jünger
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 12 (2018)
Back pain is a leading cause of disability and is strongly associated with intervertebral disc (IVD) degeneration. Reducing structural disruption and catabolism in IVD degeneration remains an important clinical challenge. Pro-oxidant and structure-mo
Externí odkaz:
https://doaj.org/article/c0b99b40da8241b3acb5ad2e352222ae
Autor:
Deepak Vashishth, Svenja Illien-Jünger, Philip Nasser, Devorah M. Natelson, Damien M. Laudier, Alon Lai, Jashvant Poeran, Divya Krishnamoorthy, Andrew Torres, Robert C. Hoy, Danielle N. D'Erminio, James C. Iatridis
Publikováno v:
J Orthop Res
Back pain and spinal pathologies are associated with obesity in juveniles and adults, yet studies identifying causal relationships are lacking and none investigate sex differences. This study determined if high fat (HF) diet causes structural and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcb05b5615347041f7d38b624051440
https://pubmed.ncbi.nlm.nih.gov/34676612
https://pubmed.ncbi.nlm.nih.gov/34676612
Autor:
Victoria Mroz, Changli Zhang, Elizabeth W. Bradley, George Zhou, Olivia M. Torre, Alon Lai, Svenja Illien-Jünger, Robert C Hoy, James C. Iatridis, Madeline P. Smith, Jennifer J. Westendorf, Damien M. Laudier
Publikováno v:
Cell Death and Disease, Vol 10, Iss 10, Pp 1-15 (2019)
Cell Death & Disease
Cell Death & Disease
Back pain is a leading cause of global disability and is strongly associated with intervertebral disc (IVD) degeneration (IDD). Hallmarks of IDD include progressive cell loss and matrix degradation. The Akt signaling pathway regulates cellularity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b305d99b970117e1a959da319b3f8c
http://link.springer.com/article/10.1038/s41419-019-1985-3
http://link.springer.com/article/10.1038/s41419-019-1985-3
Autor:
Robert C Hoy, Michael Lee, Timothy Kaseta, Thomas W. Evashwick-Rogler, Philip Nasser, Grace E. Mosley, James C. Iatridis, Alon Lai
Publikováno v:
Spine (Phila Pa 1976)
Study design A rat puncture injury intervertebral disc (IVD) degeneration model with structural, biomechanical, and histological analyses. Objective To determine if males and females have distinct responses in the IVD after injury. Summary of backgro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001bec72e1071caf1814da68bdb9a7ee
https://doi.org/10.1097/brs.0000000000003055
https://doi.org/10.1097/brs.0000000000003055
Autor:
Grace E. Mosley, James C. Iatridis, Jennifer Gansau, Damien M. Laudier, Robert C Hoy, Zachary S Gallate, Jashvant Poeran, Lawrence Zeldin
Publikováno v:
JOR Spine
Collagen plays a key structural role in both the annulus fibrosus (AF) and nucleus pulposus (NP) of intervertebral disks (IVDs). Changes in collagen content with degeneration suggest a shift from collagen type II to type I within the NP, and the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c41d6a9425aa65737d66854acc374a
https://doi.org/10.1002/jsp2.1129
https://doi.org/10.1002/jsp2.1129
Publikováno v:
Cells, Vol 9, Iss 2490, p 2490 (2020)
Cells
Cells
Cell-based therapeutics for cardiac repair have been extensively used during the last decade. Preclinical studies have demonstrated the effectiveness of adoptively transferred stem cells for enhancement of cardiac function. Nevertheless, several cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f635adb9215e127d72e077c65624c4
https://www.mdpi.com/2073-4409/9/11/2490
https://www.mdpi.com/2073-4409/9/11/2490
Autor:
Lena Ma, Tomoko Okuno, Lindsay Kraus, Faustina Nguyen, Yijun Yang, Robert C Hoy, Mohsin Khan, Sadia Mohsin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
The adult heart following injury such as a myocardial infarction forms a fibrotic scar associated with transformation of resident cardiac fibroblasts into myofibroblast, accelerating cardiac remodeling and dysfunction. Cell therapies provide a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b03475d1400b1f3d7547b64152e2e2