Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Robert C Grant"'
Autor:
Sarah M Goodday, Emma Karlin, Alexa Brooks, Carol Chapman, Christiana Harry, Nelly Lugo, Shannon Peabody, Shazia Rangwala, Ella Swanson, Jonell Tempero, Robin Yang, Daniel R Karlin, Ron Rabinowicz, David Malkin, Simon Travis, Alissa Walsh, Robert P Hirten, Bruce E Sands, Chetan Bettegowda, Matthias Holdhoff, Jessica Wollett, Kelly Szajna, Kallan Dirmeyer, Anna Dodd, Shawn Hutchinson, Stephanie Ramotar, Robert C Grant, Adrien Boch, Mackenzie Wildman, Stephen H Friend
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e57827 (2024)
BackgroundWearable digital health technologies and mobile apps (personal digital health technologies [DHTs]) hold great promise for transforming health research and care. However, engagement in personal DHT research is poor. ObjectiveThe objective o
Externí odkaz:
https://doaj.org/article/5e84f318bf6a46d793a1a2a87e064a7b
Autor:
Kai Duan, Gun-Ho Jang, Robert C. Grant, Julie M. Wilson, Faiyaz Notta, Grainne M. O’Kane, Jennifer J. Knox, Steven Gallinger, Sandra Fischer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Combination chemotherapy, either modified FOLFIRINOX (mFFX) or gemcitabine–nabpaclitaxel, are used in the treatment of most patients with advanced pancreatic ductal adenocarcinoma (PDAC), yet robust biomarkers of outcome are currently lack
Externí odkaz:
https://doaj.org/article/73ccc66b28ee408c885e22f743c92bee
Autor:
Bryn Golesworthy, Yifan Wang, Amanda Tanti, Alain Pacis, Joan Miguel Romero, Adeline Cuggia, Celine Domecq, Guillaume Bourdel, Robert E. Denroche, Gun Ho Jang, Robert C. Grant, Ayelet Borgida, Barbara T. Grünwald, Anna Dodd, Julie M. Wilson, Guillaume Bourque, Grainne M. O’Kane, Sandra E. Fischer, Chelsea Maedler Kron, Pierre-Olivier Fiset, Atilla Omeroglu, William D. Foulkes, Steven Gallinger, Marie-Christine Guiot, Zu-Hua Gao, George Zogopoulos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The immune contexture of pancreatic ductal adenocarcinoma (PDAC) is generally immunosuppressive. A role for immune checkpoint inhibitors (ICIs) in PDAC has only been demonstrated for the rare and hypermutated mismatch repair (MMR) deficient (MMR-d) s
Externí odkaz:
https://doaj.org/article/05e7545055d64a62972ea705edc792bf
Autor:
Lucy X. Ma, Yifan Wang, Osvaldo Espin-Garcia, Michael J. Allen, Gun Ho Jang, Amy Zhang, Anna Dodd, Stephanie Ramotar, Shawn Hutchinson, Mustapha Tehfe, Ravi Ramjeesingh, James Biagi, Julie M. Wilson, Faiyaz Notta, Sandra E. Fischer, George Zogopoulos, Steven Gallinger, Robert C. Grant, Rama Khokha, Nathan Chan, Barbara T. Grünwald, Jennifer J. Knox, Grainne M. O’Kane
Publikováno v:
British Journal of Cancer. 128:1916-1921
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bca148ea02eb21806d86de2e65a161c8
https://doi.org/10.1038/s41416-023-02214-0
https://doi.org/10.1038/s41416-023-02214-0
Autor:
Nicholas Holzapfel, Amy Zhang, Woo-Jin Choi, Robert Denroche, Gunho Jang, Anna Dodd, Roxana Bucur, Julie Wilson, Gonzalo Sapisochin, Faiyaz Notta, Robert C. Grant, Steven Gallinger, Jennifer J. Knox, Grainne M. O’Kane
Publikováno v:
Journal of Gastrointestinal Oncology. 14:379-389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::757834b11b9fc6aab52a3266eef62b1f
https://doi.org/10.21037/jgo-22-676
https://doi.org/10.21037/jgo-22-676
Autor:
Badr, Id Said, David, Buchan, Zijin, Liu, John, Kim, Ali, Hosni, James D, Brierley, Sami, Chadi, Robert C, Grant, Sangeetha, Kalimuthu, Zhihui Amy, Liu, Jelena, Lukovic
Publikováno v:
Colorectal Disease. 25:608-615
The aim of this study was to describe the baseline clinical features, treatment patterns and outcomes in rectal squamous cell carcinoma (SCC).This is a retrospective study of patients with rectal SCC treated at the Princess Margaret Cancer Centre (To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458eb1a88f076a3bc1d07760bd268fdb
https://doi.org/10.1111/codi.16417
https://doi.org/10.1111/codi.16417
Autor:
Grainne M. O'Kane, Jennifer J. Knox, Robert C. Grant, Steven Gallinger, Faiyaz Notta, George Zogopoulos, Sandra E. Fischer, Julie Wilson, Bernard Lam, James Biagi, Ravi Ramjeesingh, Mustapha Tehfe, Shawn Hutchinson, Stephanie Ramotar, Anna Dodd, Robert E. Denroche, Amy Zhang, Michael Allen, Deirdre Kelly, Yifan Wang, Gun Ho Jang, Sheron Perera
Purpose:Modified FOLFIRINOX (mFFX) and gemcitabine/nab-paclitaxel (GnP) remain standard first-line options for patients with advanced pancreatic ductal adenocarcinoma (PDAC). Human equilibrative nucleoside transporter 1 (hENT1) was hypothesized to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3043ebb9b5deae4957004105202ff8e0
https://doi.org/10.1158/1078-0432.c.6532926.v1
https://doi.org/10.1158/1078-0432.c.6532926.v1
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 1 shows the results of the Disambiguate algorithm used to assign the PDAC xenograft RNAseq reads to individual species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2551ac02968df13e31c3e40f57529427
https://doi.org/10.1158/1078-0432.22476474
https://doi.org/10.1158/1078-0432.22476474
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 9 shows the Cox proportional hazards model, integrating Moffitt transcriptomic subtype, tumour ploidy, stage and age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027feb79416c28565c2b063c69ff94c5
https://doi.org/10.1158/1078-0432.22476441.v1
https://doi.org/10.1158/1078-0432.22476441.v1
Autor:
Jennifer J. Knox, Steven Gallinger, Malcolm J. Moore, Julie M. Wilson, Faiyaz Notta, David Hedley, Neesha Dhani, Paul M. Krzyzanowski, Lee Timms, Jen Jen Yeh, Richard A. Moffitt, Ashton A. Connor, Spring Holter, Mathieu Lemire, Sangeet Ghai, John M.S. Bartlett, Ilinca M. Lungu, Danielle Pasternack, Faridah Mbabaali, Jessica K. Miller, Robert C. Grant, Shari Moura, Hamzeh Albaba, Grainne M. O'Kane, Amy Zhang, Dianne Chadwick, Sheng-Ben Liang, Bernadette Southwood, Sean Creighton, Anna Dodd, Gun-Ho Jang, Robert E. Denroche, Sandra E. Fischer, Kyaw L. Aung
Purpose: To perform real-time whole genome sequencing (WGS) and RNA sequencing (RNASeq) of advanced pancreatic ductal adenocarcinoma (PDAC) to identify predictive mutational and transcriptional features for better treatment selection.Experimental Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbe8fc5dfab94ff81688a693a53d954
https://doi.org/10.1158/1078-0432.c.6524567.v1
https://doi.org/10.1158/1078-0432.c.6524567.v1