Výsledky vyhledávání - "Robert C G Martin"

Akademický článek

Irreversible electroporation augments β-glucan induced trained innate immunity for the treatment of pancreatic ductal adenocarcinoma

Autor: Hong Li, Yan Li, Min Tan, Shu Li, Jun Yan, Robert A Mitchell, Matthew R Woeste, Rejeena Shrestha, Anne E Geller, Diego Montoya-Durango, Chuanlin Ding, Xiaoling Hu, Aaron Puckett, Traci Hayat, Kelly M McMasters, Robert C G Martin

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)

Background Pancreatic cancer (PC) is a challenging diagnosis that is yet to benefit from the advancements in immuno-oncologic treatments. Irreversible electroporation (IRE), a non-thermal method of tumor ablation, is used in treatment of select patie

Externí odkaz: https://doaj.org/article/81f07e10f9b0454480f2773ff2d338dc

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Akademický článek

Irreversible electroporation ablation (IRE) of unresectable soft tissue tumors: learning curve evaluation in the first 150 patients treated.

Autor: Prejesh Philips, David Hays, Robert C G Martin

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e76260 (2013)

BACKGROUND: Irreversible electroporation (IRE) is a novel technology that uses peri-target discrete probes to deliver high-voltage localized electric current to induce cell death without thermal-induced coagulative necrosis. "Learnability" and consis

Externí odkaz: https://doaj.org/article/d89ee3a5d45840f3a2d4e7a9884ca1f1

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Akademický článek

The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control pancreatic cancer progression

Autor: Anne E. Geller, Rejeena Shrestha, Matthew R. Woeste, Haixun Guo, Xiaoling Hu, Chuanlin Ding, Kalina Andreeva, Julia H. Chariker, Mingqian Zhou, David Tieri, Corey T. Watson, Robert A. Mitchell, Huang-ge Zhang, Yan Li, Robert C. G. Martin II, Eric C. Rouchka, Jun Yan

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)

The advent of immunotherapy has revolutionised cancer therapeutics, but its application in the context of pancreatic ductal adenocarcinoma has been limited. Here authors explore the effect of innate trained responses to fungal β-glucan and assess it

Externí odkaz: https://doaj.org/article/60896ee968874b53b16e34db9dd843ba

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Akademický článek

Multicenter randomized controlled trial and registry study to assess the safety and efficacy of the NanoKnife® system for the ablation of stage 3 pancreatic adenocarcinoma: overview of study protocols

Autor: Govindarajan Narayanan, Malcolm M. Bilimoria, Peter J. Hosein, Zhaohui Su, Kathleen M. Mortimer, Robert C. G. Martin

Publikováno v: BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background Irreversible electroporation (IRE) is a local ablation technique utilizing high voltage, low energy direct current to create nanopores in cell membrane which disrupt homeostasis and leads to cell death. Previous reports have sugge

Externí odkaz: https://doaj.org/article/517df446e4354201898909c2250a52b5

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Akademický článek

Optimizing Patient Selection for Irreversible Electroporation of Locally Advanced Pancreatic Cancer: Analyses of Survival

Autor: Matthew R. Woeste, Khaleel D. Wilson, Edward J. Kruse, Matthew J. Weiss, John D. Christein, Rebekah R. White, Robert C. G. Martin

Publikováno v: Frontiers in Oncology, Vol 11 (2022)

BackgroundIrreversible electroporation (IRE) has emerged as a viable consolidative therapy after induction chemotherapy, in which this combination has improved overall survival of locally advanced pancreatic cancer (LAPC). Optimal timing and patient

Externí odkaz: https://doaj.org/article/283b0dffc21a45ee9f9574d9cfdf0fcc

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