Zobrazeno 1 - 10
of 1 161
pro vyhledávání: '"Robert C Bast"'
Autor:
Johannes F. Fahrmann, Seyyed Mahmood Ghasemi, Chae Y. Han, Ranran Wu, Jennifer B. Dennison, Jody Vykoukal, Joseph Celestino, Karen Lu, Zhen Lu, Charles Drescher, Kim-Anh Do, Samir Hanash, Robert C. Bast, Ehsan Irajizad
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-4 (2024)
Abstract Serial CA125 and second line transvaginal ultrasound (TVS) screening in the UKCTOCS indicated a shift towards detection of earlier stage ovarian cancer (OvCa), but did not yield a significant mortality reduction. There remains a need to esta
Externí odkaz:
https://doaj.org/article/2b8812a211ae4ae9b4d76a096e3b31c8
Autor:
Kate O’Rourke
Publikováno v:
Cancer. 128:3431-3432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55aaa265f28154edfb4b0878edb62f73
https://doi.org/10.1002/cncr.34437
https://doi.org/10.1002/cncr.34437
Akademický článek
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Autor:
Jing Guo, Chunyan Wang, Ning Luo, Yuliang Wu, Wei Huang, Jihui Zhu, Weihui Shi, Jinye Ding, Yao Ge, Chunhong Liu, Zhen Lu, Robert C. Bast, Guihai Ai, Weihong Yang, Rui Wang, Caixia Li, Rong Chen, Shupeng Liu, Huajun Jin, Binghui Zhao, Zhongping Cheng
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinical and clinical studie
Externí odkaz:
https://doaj.org/article/47172d00ce154c1d97952eab624ecce7
Autor:
Jones, Carleton 'Buck'
Publikováno v:
Journal of the Arizona-Nevada Academy of Science, 2002 Jan 01. 34(2), 120-120.
Externí odkaz:
https://www.jstor.org/stable/40022784
Autor:
Xiaowen Liang, Sung Yun Jung, Lon Wolf Fong, Gamze Bildik, Joshua P. Gray, Weiqun Mao, Shuxing Zhang, Steven W. Millward, Alemayehu A. Gorfe, Yong Zhou, Zhen Lu, Robert C. Bast, Jr.
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108151- (2023)
Summary: DIRAS3 is an imprinted tumor suppressor gene encoding a GTPase that has a distinctive N-terminal extension (NTE) not found in other RAS proteins. This NTE and the prenylated C-terminus are required for DIRAS3-mediated inhibition of RAS/MAP s
Externí odkaz:
https://doaj.org/article/70cacc6af2444e3e920cbf39c22bbaf4
Autor:
Xiu Shi, Xuejiao Yu, Juan Wang, Shimin Bian, Qiutong Li, Fengqing Fu, Xinwei Zou, Lin Zhang, Robert C. Bast Jr., Zhen Lu, Lingchuan Guo, Youguo Chen, Jinhua Zhou
Publikováno v:
Molecular Oncology, Vol 16, Iss 13, Pp 2558-2574 (2022)
Salt‐inducible kinase 2 (SIK2; also known as serine/threonine‐protein kinase SIK2) is overexpressed in several cancers and has been implicated in cancer progression. However, the mechanisms by which SIK2 regulates cancer cell motility, migration
Externí odkaz:
https://doaj.org/article/79adc25e6b85439bb2e5bb149f97ac33
Publikováno v:
Oncogenesis, Vol 10, Iss 9, Pp 1-12 (2021)
Abstract To understand the role of polyploid giant cancer cells (PGCCs) in drug resistance and disease relapse, we examined the mRNA expression profile of PGCCs following treatment with paclitaxel in ovarian cancer cells. An acute activation of IL-6
Externí odkaz:
https://doaj.org/article/3cbf22e5819e4e2faf0144cacf392814
Autor:
Zhen Lu, Weiqun Mao, Hailing Yang, Janice M. Santiago-O’Farrill, Philip J. Rask, Jayanta Mondal, Hu Chen, Cristina Ivan, Xiuping Liu, Chang-Gong Liu, Yuanxin Xi, Kenta Masuda, Eli M. Carrami, Meng Chen, Yitao Tang, Lan Pang, David S. Lakomy, George A. Calin, Han Liang, Ahmed A. Ahmed, Hariprasad Vankayalapati, Robert C. Bast Jr.
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Poly(ADP-ribose) polymerase inhibitors (PARP inhibitors) have had an increasing role in the treatment of ovarian and breast cancers. PARP inhibitors are selectively active in cells with homologous recombination DNA repair deficiency caused by mutatio
Externí odkaz:
https://doaj.org/article/2135cd9f007a441e941965d7b77e03eb