Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Robert Brownlie"'
Autor:
GuanQun Liu, Yao Lu, Sathya N. Thulasi Raman, Fang Xu, Qi Wu, Zhubing Li, Robert Brownlie, Qiang Liu, Yan Zhou
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
RIG-I senses cytoplasmic viral RNA, resulting in induction of an antiviral response. Here, the authors identify nuclear RIG-I and show that it binds nuclear influenza A virus RNA, resulting in a cooperative interferon induction along with its cytopla
Externí odkaz:
https://doaj.org/article/f9f0aa1f28d042be8ac6b3988ac72a18
Autor:
Robert Brownlie, Wanda C Allen, Christopher D. Richardson, Peter Robertson, Ali Toloue Ostadgavahi, Gary Sisson, Ryan Booth, Darryl Falzarano, Matthew Miller, May El Sherif, Michelle Warhuus, Nichole McMullen
Publikováno v:
The Journal of Infection in Developing Countries. 15:653-656
Understanding the efficacy and durability of heterologous immunization schedules against SARS-CoV-2 is critical, as supply demands and vaccine choices become significant issues in the global vaccination strategy. Here we characterize the neutralizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70a37e5e0e20558ec67e5a88b7df584
https://doi.org/10.3855/jidc.15368
https://doi.org/10.3855/jidc.15368
Autor:
Robert Brownlie, Brenda Allan, J. Alex Pasternak, Milan R. Obradovic, Heather L. Wilson, Siew Hon Ng
Publikováno v:
Veterinary Microbiology. 235:270-279
Lawsonia intracellularis is an obligate intracellular microorganism and the causative agent of porcine proliferative enteropathy. Due to its obligate intracellular nature, characterization of antigens and proteins involved in host-pathogen interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfba33aa3864233511006df721268c4
https://doi.org/10.1016/j.vetmic.2019.07.014
https://doi.org/10.1016/j.vetmic.2019.07.014
Publikováno v:
Developmental & Comparative Immunology. 127:104271
The α- and β-adrenergic receptors (ARs) bind the stress hormones epinephrine (E), norepinephrine (NE), and dopamine and activate diverse physiological responses. A lack of information on AR gene expression in leukocytes limits our understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13801a6903ebf8ed394d1f86542d8220
https://doi.org/10.1016/j.dci.2021.104271
https://doi.org/10.1016/j.dci.2021.104271
Autor:
S. van Drunen Littel-van den Hurk, Volker Gerdts, Andrew A. Potter, Ravendra Garg, Robert Brownlie, Laura J.P. Latimer
Publikováno v:
Vaccine. 35:7139-7146
Human parainfluenza virus type 3 (PIV3) is a major cause of lower respiratory disease i.e. bronchitis, bronchiolitis or pneumonia, in infants and young children. Presently there is no licensed vaccine against PIV3. To produce an effective subunit vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40c4a4f4131ba7042aff48b638f9eca
https://doi.org/10.1016/j.vaccine.2017.10.095
https://doi.org/10.1016/j.vaccine.2017.10.095
Autor:
Heather L. Wilson, Siew Hon Ng, Kezia R. Fourie, Milan R. Obradovic, Robert Brownlie, Pooja Choudhary, Sanjeev K. Anand
Publikováno v:
Veterinary Immunology and Immunopathology. 237:110256
Lawsonia intracellularis is an economically important bacterium that causes ileitis in pigs. Current vaccines for L. intracellularis do not allow for differentiation between infected and vaccinated animals (DIVA), which is beneficial for disease trac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedfa691a121e7bd06004e6ac74ea988
https://doi.org/10.1016/j.vetimm.2021.110256
https://doi.org/10.1016/j.vetimm.2021.110256
Autor:
Sylvia van Drunen Littel-van den Hurk, Sams Mohammad Anowar Sadat, Marlene Snider, Ravendra Garg, Robert Brownlie
Publikováno v:
Vaccine. 35:3466-3473
Bovine viral diarrhea virus (BVDV) is one of the most serious pathogens in cattle. Recently, we developed a novel adjuvant platform (TriAdj) that includes a toll-like receptor 3 agonist, poly (I:C); an innate defense regulatory peptide; and water-sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1717c97a8db97d9c923cd22c4c5f1f39
https://doi.org/10.1016/j.vaccine.2017.05.029
https://doi.org/10.1016/j.vaccine.2017.05.029
Autor:
Shelby Landreth, Yan Zhou, Yao Lu, Robert Brownlie, Sylvia van Drunen Littel-van den Hurk, Amit Gaba, GuanQun Liu, Volker Gerdts
Publikováno v:
Vaccine. 38(10)
The highly pathogenic avian influenza (HPAI) H5N1 viruses and their spillover into the human population pose substantial economic and public health threats. Although antiviral drugs have some effect in treating influenza infection, vaccination is sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5125580cf7b8695b6e420936e20e61b9
https://pubmed.ncbi.nlm.nih.gov/32014270
https://pubmed.ncbi.nlm.nih.gov/32014270
Autor:
Robert Brownlie, Suresh K. Tikoo, Kuan Zhang, Soumya Sucharita, Marlene Snider, Tara Donovan, Sylvia van Drunen Littel-van den Hurk
Publikováno v:
Journal of Virology. 93
Bovine herpesvirus 1 (BoHV-1) infects bovine species, causing respiratory infections, genital disorders and abortions. VP8 is the most abundant tegument protein of BoHV-1 and is critical for virus replication in cattle. In this study, the cellular tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ef4d6f93cc1cd7d2e162dbbeae98e9
https://doi.org/10.1128/jvi.02151-18
https://doi.org/10.1128/jvi.02151-18
Publikováno v:
Journal of Virology. 90:4889-4904
The U L 47 gene product, VP8, is the most abundant tegument protein of bovine herpesvirus 1 (BoHV-1). Previously, we demonstrated that a U L 47 -deleted BoHV-1 mutant (BoHV1-ΔU L 47) exhibits 100-fold-reduced virulence in vitro and is avirulent in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a708dd1eaa5a6e803e02bdb9be8398
https://doi.org/10.1128/jvi.00017-16
https://doi.org/10.1128/jvi.00017-16