Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robert Bronstein"'
Autor:
Nehaben A. Gujarati, Bismark O. Frimpong, Malaika Zaidi, Robert Bronstein, Monica P. Revelo, John D. Haley, Igor Kravets, Yiqing Guo, Sandeep K. Mallipattu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Diabetic kidney disease (DKD) is the main cause of chronic kidney disease worldwide. While injury to the podocytes, visceral epithelial cells that comprise the glomerular filtration barrier, drives albuminuria, proximal tubule (PT) dysfuncti
Externí odkaz:
https://doaj.org/article/cdbd1df04e2d45b397f79f55bb2a24c9
Autor:
Arafat Meah, Vadanasundari Vedarethinam, Robert Bronstein, Nehaben Gujarati, Tanya Jain, Sandeep K. Mallipattu, Yueming Li, Jun Wang
Publikováno v:
Biosensors, Vol 13, Iss 9, p 852 (2023)
High-multiplex detection of protein biomarkers across tissue regions has been an attractive spatial biology approach due to significant advantages over traditional immunohistochemistry (IHC) methods. Different from most methods, spatial multiplex in
Externí odkaz:
https://doaj.org/article/03deb02cbeac4dbfaa5ba1d5639cbda2
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Kidney disease is an epidemic that affects more than 600 million people worldwide. The socioeconomic impacts of the disease disproportionately affect Hispanic and non-Hispanic Black Americans, making the disease an issue of social inequality. The urg
Externí odkaz:
https://doaj.org/article/4a435f27d5924c458214ce48fe7a7291
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Mouse cortical development relies heavily on a delicate balance between neurogenesis and gliogenesis. The lateral ventricular zone produces different classes of excitatory pyramidal cells until just before birth, when the production of astroglia begi
Externí odkaz:
https://doaj.org/article/af9bee6d822941b8a51932743d0614c1
Autor:
Ariel B Abraham, Robert Bronstein, Avanish S Reddy, Mirjana Maletic-Savatic, Adan Aguirre, Stella E Tsirka
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84838 (2013)
Neural stem and progenitor cells (NSCs/NPCs) are distinct groups of cells found in the mammalian central nervous system (CNS). Previously we determined that members of the High Mobility Group (HMG) B family of chromatin structural proteins modulate N
Externí odkaz:
https://doaj.org/article/fe51f4e334b84971945d9ad822c5f947
Publikováno v:
Journal of the American Society of Nephrology. 34:737-750
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f7f65562add0c7d300d007ddd7a5f4
https://doi.org/10.1681/asn.0000000000000104
https://doi.org/10.1681/asn.0000000000000104
Autor:
John Cijiang He, Yaqi Yang, Agnieszka B. Bialkowska, David J. Salant, Vincent W. Yang, John D. Haley, Nehaben A. Gujarati, Yiqing Guo, Robert Bronstein, Sandeep K. Mallipattu, Jesse Pace, Chelsea Estrada
Publikováno v:
Science Advances. 7
Podocyte loss triggering aberrant activation and proliferation of parietal epithelial cells (PECs) is a central pathogenic event in proliferative glomerulopathies. Podocyte-specific Krüppel-like factor 4 (KLF4), a zinc-finger transcription factor, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89027b7270677cada3aedd649185e4ab
https://doi.org/10.1126/sciadv.abg6600
https://doi.org/10.1126/sciadv.abg6600
The transcription factor estrogen receptor α (ERα) is a principal regulator of sex differences in the vertebrate brain and can modulate mood, behavior, and energy balance in females and males. However, the genes regulated by ERα in the brain remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0d67be52384246546b162b8fabd6ba5
https://doi.org/10.1101/2020.10.21.349290
https://doi.org/10.1101/2020.10.21.349290
Autor:
Robert Bronstein, Stella E. Tsirka
Tissue-type plasminogen activator (tPA) is a protein whose enzymatic and nonenzymatic properties make it critical to normal and pathological events within the central nervous system. Here we outline the known roles of tPA in common proteolytic and he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b8e81b1149cc1efe06f476b36efd42
https://doi.org/10.1016/b978-0-12-803058-5.00060-6
https://doi.org/10.1016/b978-0-12-803058-5.00060-6
Autor:
Robert Bronstein, Erin H. Norris, Sidney Strickland, Justin Paul, Daria Zamolodchikov, Hyung Jin Ahn, Marta Cortes-Canteli, Shivaprasad Bhuvanendran, Katherine M. Fenz
Publikováno v:
Neuron. 66(5):695-709
Alzheimer's disease (AD) is a neurodegenerative disorder in which vascular pathology plays an important role. Since the beta-amyloid peptide (Abeta) is a critical factor in this disease, we examined its relationship to fibrin clot formation in AD. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f6a956b405c205225b748ef743e712