Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robert Betterton"'
Autor:
Erica I Williams, Robert Betterton, Joshua A Stanton, Jeffrey J Lochhead, Thomas P Davis, Patrick T Ronaldson
Publikováno v:
Stroke. 54
Clinical development of new drugs for ischemic stroke has been challenging. In contrast, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (i.e., statins) are routinely administered to stroke patients because they improve neurological outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dfb50d08e463d5e4a26622596f1fe6d
https://doi.org/10.1161/str.54.suppl_1.tp205
https://doi.org/10.1161/str.54.suppl_1.tp205
Autor:
Robert Betterton, Erica I Williams, Joshua Stanton, Jeffrey Lochhead, Tom Davis, Patrick Ronaldson
Publikováno v:
Stroke. 54
Objectives: We have shown that transforming growth factor-β (TGF-β)/activin-like kinase 1 (ALK1) signaling at the blood-brain barrier (BBB) can regulate organic anion transporting polypeptide 1a4 (Oatp1a4), a transporter involved in brain uptake of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9835402b64986f28f1a1d810a461cf8d
https://doi.org/10.1161/str.54.suppl_1.tp209
https://doi.org/10.1161/str.54.suppl_1.tp209
Autor:
Joshua Stanton, Erica I Williams, Robert Betterton, Jeffrey Lochhead, Thomas Davis, Patrick Ronaldson
Publikováno v:
Stroke. 54
Purpose: Cationic drugs have often been considered for stroke treatment but their utility is dependent upondelivery across the blood-brain barrier (BBB). This process can involve transporters for cationic substratessuch as organic cation transporters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dba37c64474fba09ebc0f14a3ee17a6b
https://doi.org/10.1161/str.54.suppl_1.wp244
https://doi.org/10.1161/str.54.suppl_1.wp244