Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robert Bergstrand"'
Publikováno v:
Cardiovascular Drugs and Therapy. 10:539-547
The aim of the present study was to assess the frequency dependency of the effects of almokalant, a selective class III antiarrhythmic drug, on ventricular repolarization using recordings of monophasic action potentials and measurements of ventricula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397ede397e5fdc199a03bfbadedf36ac
https://doi.org/10.1007/bf00050994
https://doi.org/10.1007/bf00050994
Publikováno v:
Journal of Cardiovascular Pharmacology. 26:530-540
Almokalant, a recently developed potassium-channel blocker, has exhibited properties of a selective class III agent in vitro and in animal experiments. We report the first invasive study in humans in which the electrophysiological characteristics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9dbed73372c4cb0ed344e11d13dd354
https://doi.org/10.1097/00005344-199510000-00005
https://doi.org/10.1097/00005344-199510000-00005
Autor:
Robert Bergstrand, Börje Darpö, Nils Edvardsson, Christer Gottfridsson, Olle Almgren, Bengt Sandstedt, Catharina Bäärnhielm
Publikováno v:
Journal of Cardiovascular Pharmacology. 25:681-690
Almokalant, (4-(3-ethyl(3-propylsulfinyl)propyl)amino)-2-hydroxy-propoxy)- benzonitrile), is a newly developed Ik channel blocker that exhibits pure class III effects. Using a noninvasive approach with transesophageal atrial stimulation (TAS), we wis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8554236145bb405e978b0b1f60e2154
https://doi.org/10.1097/00005344-199505000-00001
https://doi.org/10.1097/00005344-199505000-00001
Publikováno v:
Clinical Drug Investigation. 9:67-71
12 healthy male volunteers participated in this open, randomised, crossover study. On 2 study days at least 6 days apart the volunteers were given a single oral dose of lansoprazole 30mg with or without a standardised breakfast. When lansoprazole was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4233b7542dba68851ba5b58e95a89385
https://doi.org/10.2165/00044011-199509020-00002
https://doi.org/10.2165/00044011-199509020-00002
Autor:
Harold L. Kennedy, Maria Mori Brooks, Allan H. Barker, Robert Bergstrand, Melissa L. Huther, Donald S. Beanlands, J. Thomas Bigger, Sidney Goldstein, null The CAST Investigators
Publikováno v:
The American Journal of Cardiology. 74:674-680
The Cardiac Arrhythmia Suppression Trial (CAST) showed antiarrhythmic drug suppression of asymptomatic or mildly symptomatic ventricular arrhythmias in survivors of myocardial infarction to be harmful. This study retrospectively searched the CAST res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5473a2a4475d6a2bcf9dc0fa3ced127
https://doi.org/10.1016/0002-9149(94)90308-5
https://doi.org/10.1016/0002-9149(94)90308-5
Publikováno v:
Pharmaceutical Research. 10:28-34
Steady-state bioavailability and day-to-day variability of plasma levels were evaluated in 18 healthy male subjects in a crossover study of multiple once-daily administration of two novel oral drug delivery systems of metoprolol and an immediate-rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40eff1c6720e4194e907c04323f5a5d4
https://doi.org/10.1023/a:1018960626925
https://doi.org/10.1023/a:1018960626925
Autor:
Inger Skånberg, C. Cederberg, Robert Bergstrand, Tommy B. Andersson, Per-Olof Lagerstrom, Sven Eriksson
Publikováno v:
Gastroenterology. 101:943-947
This study was performed to investigate the possible influence of repeated omeprazole dosing on the metabolism of caffeine, which has been shown to reflect the activity of one specific enzyme within the hepatic cytochrome P450 family, P450IA2. Ten he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7214d257dea29d5764ba7b11530c64f0
https://doi.org/10.1016/0016-5085(91)90719-2
https://doi.org/10.1016/0016-5085(91)90719-2
Autor:
Carl-Gunnar Regårdh, Bertil Abrahamsson, Bertil Olofsson, Robert Bergstrand, P. W. Lucker, Anders Sandberg, Ingrid Wieselgren
Publikováno v:
The Journal of Clinical Pharmacology. 30:S46-S54
Four studies using different daily doses (100 mg, 200 mg, 300 mg and 400 mg) have examined the bioequivalence of the once daily formulation metoprolol CR/ZOK and conventional metoprolol tablets (CT). These studies showed metoprolol CR/ZOK to have a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da56377b47687142506b5825a193aaf1
https://doi.org/10.1002/j.1552-4604.1990.tb03495.x
https://doi.org/10.1002/j.1552-4604.1990.tb03495.x
Publikováno v:
The Journal of Clinical Pharmacology. 30:S17-S27
Four studies of identical design, each on 18 young healthy subjects, were undertaken to study the pharmacokinetics and beta 1-receptor blockade at steady state after a once daily dose (od) of 100, 200, 300 and 400 mg of metoprolol CR/ZOK (a new contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fd89eddca4a3b7e06746f27c06e2df
https://doi.org/10.1002/j.1552-4604.1990.tb03491.x
https://doi.org/10.1002/j.1552-4604.1990.tb03491.x
Autor:
Harry J.G.M. Crijns, Olle Almgren, Robert Bergstrand, Ans C.P. Wiesfeld, Kong I. Lie, Hans L. Hillege
Publikováno v:
American Heart Journal, 126(4), 1008-1011. MOSBY-ELSEVIER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfa5ad0dbf9d7912aae46265b3f297b
https://research.rug.nl/en/publications/77c2301a-2800-457b-99f8-195ecbe0ad7d
https://research.rug.nl/en/publications/77c2301a-2800-457b-99f8-195ecbe0ad7d
