Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Robert Beaty"'
Autor:
Anirban Maitra, Gregory J. Riggins, Alfonso Diaz, Fernando Pimentel, Luis Ibañez, Ivan Roa, Michael Mullendore, Seung-Mo Hong, Georg Feldmann, Robert Beaty, Jennifer Edwards, Francisco Murillo, Pedram Argani, Juan C. Roa, Alejandro Corvalan, Hector Alvarez
Background: Gallbladder cancer (GBC) is an uncommon neoplasm in the United States, but one with high mortality rates. This malignancy remains largely understudied at the molecular level such that few targeted therapies or predictive biomarkers exist.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a330592e76fc3501a486901e4aa9b56
https://doi.org/10.1158/1078-0432.c.6516931
https://doi.org/10.1158/1078-0432.c.6516931
Autor:
Anirban Maitra, Gregory J. Riggins, Alfonso Diaz, Fernando Pimentel, Luis Ibañez, Ivan Roa, Michael Mullendore, Seung-Mo Hong, Georg Feldmann, Robert Beaty, Jennifer Edwards, Francisco Murillo, Pedram Argani, Juan C. Roa, Alejandro Corvalan, Hector Alvarez
Supplementary Data from Serial Analysis of Gene Expression Identifies Connective Tissue Growth Factor Expression as a Prognostic Biomarker in Gallbladder Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c630adc4ae31f8e1188391e96919a89
https://doi.org/10.1158/1078-0432.22439470.v1
https://doi.org/10.1158/1078-0432.22439470.v1
Autor:
Anirban Maitra, William Matsui, Kathleen L. Gabrielson, Antonio Jimeno, Christine Iacobuzio-Donahue, Hector Alvarez, Collins Karikari, Michael Mullendore, Robert Beaty, Djahida Bedja, Volker Fendrich, Surajit Dhara, Georg Feldmann
Supplementary Table 1 and Figure Legend from Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53f93e1ace940fd9e48f4344f4d8f30
https://doi.org/10.1158/0008-5472.22366886.v1
https://doi.org/10.1158/0008-5472.22366886.v1
Autor:
Anirban Maitra, William Matsui, Kathleen L. Gabrielson, Antonio Jimeno, Christine Iacobuzio-Donahue, Hector Alvarez, Collins Karikari, Michael Mullendore, Robert Beaty, Djahida Bedja, Volker Fendrich, Surajit Dhara, Georg Feldmann
Supplementary Figure 1 from Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a1833e25d60ee31b6070fcf49a8751
https://doi.org/10.1158/0008-5472.22366889.v1
https://doi.org/10.1158/0008-5472.22366889.v1
Autor:
Anirban Maitra, William Matsui, Kathleen L. Gabrielson, Antonio Jimeno, Christine Iacobuzio-Donahue, Hector Alvarez, Collins Karikari, Michael Mullendore, Robert Beaty, Djahida Bedja, Volker Fendrich, Surajit Dhara, Georg Feldmann
In the context of pancreatic cancer, metastasis remains the most critical determinant of resectability, and hence survival. The objective of this study was to determine whether Hedgehog (Hh) signaling plays a role in pancreatic cancer invasion and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3994901d7a9dce68da1b08ddd45da849
https://doi.org/10.1158/0008-5472.c.6495335
https://doi.org/10.1158/0008-5472.c.6495335
Autor:
Hong Liang, Mihoko Kamiyama, Jun O. Liu, Robert Beaty, F. William Schuler, Joong Sup Shim, Balasubramanyam Karanam, Ming Tseh Lin, James R. Eshleman, Hirohiko Kamiyama, Ralph H. Hruban, H. A. Jinnah, Manuel Hidalgo, Collins Karikari, Elizabeth M. Jaffee, Anirban Maitra, Guanglan Mo, Sherri Rauenzahn, Antonio Jimeno, Georg Feldmann, Michael Mullendore, Li Hua, Richard B.S. Roden
Publikováno v:
Clinical Cancer Research. 19:1139-1146
Purpose: High-throughput chemosensitivity testing of low-passage cancer cell lines can be used to prioritize agents for personalized chemotherapy. However, generating cell lines from primary cancers is difficult because contaminating stromal cells ov
Autor:
Emmanouil P. Pappou, William Matsui, David Feller-Kopman, Lonny Yarmus, Yi Cai, Carine Robert, Il Minn, Alana L. Welm, James C. Harris, Robert Beaty, Huili Li, Feyruz V. Rassool, Jean Pierre J. Issa, James Shin, Vered Stearns, Yoon Young Jang, Yi Chun Lin, Nita Ahuja, Cynthia A. Zahnow, Saul J. Sharkis, Kirsten Harbom, Hsing-Chen Tsai, Leander Van Neste, Ray Whay Chiu Yen, Malcolm V. Brock, Stephen B. Baylin
Publikováno v:
Cancer Cell. 21:430-446
SummaryReversal of promoter DNA hypermethylation and associated gene silencing is an attractive cancer therapy approach. The DNA methylation inhibitors decitabine and azacitidine are efficacious for hematological neoplasms at lower, less toxic, doses
Autor:
Volker Fendrich, Savita Bisht, Michael Mullendore, Robert Beaty, Georg Feldmann, Nabeel Bardeesy, Nils Habbe, Collins Karikari, Anirban Maitra, Surajit Dhara, Michel M. Ouellette, Wayne Yu, Hector A Alvarez
Publikováno v:
Gut. 57:1420-1430
Background and aims: Pancreatic cancer is among the most dismal of human malignancies. Current therapeutic strategies are virtually ineffective in controlling advanced, metastatic disease. Recent evidence suggests that the Hedgehog signalling pathway
Autor:
Robert Beaty, Rosana Delcelo, Janete M. Cerutti, Jennifer Shoemaker, Pedro Michaluart, Gisele Oler, Gregory J. Riggins
Publikováno v:
Cancer Research. 67:7885-7892
Biomarkers of papillary thyroid carcinoma (PTC) metastasis can accurately identify metastatic cells and aggressive tumor behavior. To find new markers, serial analysis of gene expression (SAGE) was done on three samples from the same patient: normal
Autor:
Robert Beaty, Kathy Boon, James E. Conway, Gregory J. Riggins, Jennifer B. Edwards, I-Mei Siu
Publikováno v:
Journal of Neuro-Oncology. 81:241-248
Glioblastomas are a highly aggressive brain tumor, with one of the highest rates of new blood vessel formation. In this study we used a combined experimental and bioinformatics strategy to determine which genes were highly expressed and specific for