Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Robert B. Wellner"'
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 451:642-645
Previously (Wellner et al., Pflugers Arch 441:49-56, 2000) we suggested that the localization of the aquaporins (AQPs) AQP5 and AQP8 in the apical and basolateral membranes of rat submandibular gland (SMG) acinar cells, respectively, provides for tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59071ab114464263ecd1f344eb9d66be
https://doi.org/10.1007/s00424-005-1489-0
https://doi.org/10.1007/s00424-005-1489-0
Publikováno v:
Tissue Engineering. 11:1449-1458
To reengineer polarized epithelial cell functions directly in situ, or ex vivo in the fabrication of an artificial organ, it is necessary to understand mechanisms that account for polarized membrane sorting. We have used the aquaporins (AQPs), a fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41523292dcc11ff13f66ba1a442b381a
https://doi.org/10.1089/ten.2005.11.1449
https://doi.org/10.1089/ten.2005.11.1449
Publikováno v:
Biochemical and Biophysical Research Communications. 330:172-177
AQP5 and AQP8 possess targeting/retention motifs which mediate their localization to the apical and basolateral membranes, respectively, of polarized MDCK-II cells. As targeting/retention motifs have been localized to the N- or C-termini of other AQP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551f64c5c7b84437e30f14a0800ba0a7
https://doi.org/10.1016/j.bbrc.2005.02.146
https://doi.org/10.1016/j.bbrc.2005.02.146
Autor:
Stanley R. Pillemer, Anastasia L. Sowers, James B. Mitchell, Ana P. Cotrim, Angelo Russo, Joseph M. Vitolo, Bruce J. Baum, Robert B. Wellner
Publikováno v:
Clinical Cancer Research. 10:1807-1812
Purpose: Radiotherapy is commonly used to treat a majority of patients with head and neck cancers. The long-term radiation-induced reduction of saliva output significantly contributes to the posttreatment morbidity experienced by these patients. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e022e423b20b6c2964e01798e6fd385
https://doi.org/10.1158/1078-0432.ccr-03-0194
https://doi.org/10.1158/1078-0432.ccr-03-0194
Autor:
A.T.M. Shamsul Hoque, Lorena Baccaglini, Vidya Sankar, Albert Kingman, Corinne M. Goldsmith, Bruce J. Baum, Carl J. Wheeler, Kerry M. Barnhart, Robert S. Redman, Robert B. Wellner
Publikováno v:
The Journal of Gene Medicine. 3:82-90
BACKGROUND Previously we have shown that gene transfer to salivary gland epithelial cells readily occurs via recombinant adenoviruses, although the response is short-lived and results in a potent host immune response. The aim of the present study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2f248ef1e875d7a2854819921d8efee
https://doi.org/10.1002/1521-2254(2000)9999:9999<::aid-jgm151>3.0.co
https://doi.org/10.1002/1521-2254(2000)9999:9999<::aid-jgm151>3.0.co
Publikováno v:
Pflügers Archiv. 441:49-56
It is possible that, during primary saliva formation, aquaporins (AQPs) facilitate transcellular water flow across acinar cells to the lumina of salivary glands. In the rat submandibular gland (rSMG) AQP5 is localized in the apical membranes of acina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca871a13421c6965d328a16f60b68a9
https://doi.org/10.1007/s004240000396
https://doi.org/10.1007/s004240000396
Autor:
Lorena Baccaglini, Doron J. Aframian, Robert B. Wellner, Bruce J. Baum, Chuantian Ding, A.T.M. Shamsul Hoque, Brian O'Connell, Seiichi Yamano, Changyu Zheng, Corinne M. Goldsmith
Publikováno v:
International Journal of Oral and Maxillofacial Surgery. 29:163-166
The potential applications of gene transfer technology to all branches of medicine are increasing. It is quite likely that within the next 10-20 years surgical practice routinely will utilize gene transfer, at least adjunctively. The purpose of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a7278ac57c3ff1cb6761ea6329bf9d
https://doi.org/10.1016/s0901-5027(00)80086-7
https://doi.org/10.1016/s0901-5027(00)80086-7
Autor:
Hisako Yamagishi, Albert F. Parlow, Mark E. Berkman, Corinne M. Goldsmith, Julie Chao, Jane C. Atkinson, Bruce J. Baum, Lorena Baccaglini, Hideaki Kagami, Songlin Wang, Robert B. Wellner, A.T.M. Shamsul Hoque, Yitzhak Marmary
Publikováno v:
Human Gene Therapy. 10:2789-2797
Previously (Kagami et al. Hum. Gene Ther. 1996;7:2177-2184) we have shown that salivary glands are able to secrete a transgene-encoded protein into serum as well as saliva. This result and other published data suggest that salivary glands may be a us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1607fbcebab992208f54aa96075db573
https://doi.org/10.1089/10430349950016528
https://doi.org/10.1089/10430349950016528
Autor:
Albert F. Parlow, Corinne M. Goldsmith, Yitzhak Marmary, Xinjun He, Lynnette K. Nieman, Martin Kriete, Kazuhito Satomura, Pamela Gehron Robey, Bruce J. Baum, Robert B. Wellner
Publikováno v:
Endocrinology. 140:260-265
We have constructed a recombinant, replication-deficient, first-generation adenovirus-encoding mouse GH (mGH), AdCMVmGH. This virus directed mGH production from an epithelial cell line in vitro in a dose-dependent manner. When injected into the quadr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e94549dd3c7eee285044c94e5e8796c
https://doi.org/10.1210/endo.140.1.6400
https://doi.org/10.1210/endo.140.1.6400
Autor:
Christine Delporte, J A Kulakusky, Virginia R. Braddon, Corinne M. Goldsmith, A. T. M. S. Hoque, Bruce J. Baum, Robert B. Wellner
Publikováno v:
Biochemical and Biophysical Research Communications. 246:584-588
AdhAQP1, a recombinant adenovirus encoding the human water channel aquaporin 1 (AQP1), has been shown to be useful for gene therapy of salivary glands rendered hypofunctional following irradiation. Here we utilized AdhAQP1 to examine the relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efbbf5a8b4f62e644388c6503485695
https://doi.org/10.1006/bbrc.1998.8668
https://doi.org/10.1006/bbrc.1998.8668