Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Robert B. Stein"'
Autor:
Yury Patskovsky, Aswin Natarajan, Larysa Patskovska, Samantha Nyovanie, Bishnu Joshi, Benjamin Morin, Christine Brittsan, Olivia Huber, Samuel Gordon, Xavier Michelet, Florian Schmitzberger, Robert B. Stein, Mark A. Findeis, Andy Hurwitz, Marc Van Dijk, Eleni Chantzoura, Alvaro S. Yague, Daniel Pollack Smith, Jennifer S. Buell, Dennis Underwood, Michelle Krogsgaard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Altered protein phosphorylation in cancer cells often leads to surface presentation of phosphopeptide neoantigens. However, their role in cancer immunogenicity remains unclear. Here we describe a mechanism by which an HLA-B*0702-specific acu
Externí odkaz:
https://doaj.org/article/90c3efa5a9bc4657b99b525a37d24797
Autor:
Yury Patskovsky, Aswin Natarajan, Larysa Patskovska, Samantha Nyovanie, Bishnu Joshi, Benjamin Morin, Christine Brittsan, Olivia Huber, Samuel Gordon, Xavier Michelet, Florian Schmitzberger, Robert B. Stein, Mark A. Findeis, Andy Hurwitz, Marc Van Dijk, Eleni Chantzoura, Alvaro S. Yague, Daniel Pollack Smith, Jennifer S. Buell, Dennis Underwood, Michelle Krogsgaard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/728e056355c04efaad198cf4c8ba6b89
Autor:
Armen R. Karapetyan, Chawaree Chaipan, Katharina Winkelbach, Sandra Wimberger, Jun Seop Jeong, Bishnu Joshi, Robert B. Stein, Dennis Underwood, John C. Castle, Marc van Dijk, Volker Seibert
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Adoptive T cell therapy using patient T cells redirected to recognize tumor-specific antigens by expressing genetically engineered high-affinity T-cell receptors (TCRs) has therapeutic potential for melanoma and other solid tumors. Clinical trials im
Externí odkaz:
https://doaj.org/article/9673919d3cd542e98438952fe7b716f0
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mutation-derived neoantigens distinguish tumor from normal cells. T cells can sense the HLA-presented mutations, recognize tumor cells as non-self and destroy them. Therapeutically, immunotherapy antibodies can increase the virulence of the immune sy
Externí odkaz:
https://doaj.org/article/586ad57d3b344640b7693de49af58947
Autor:
Yury Patskovsky, Aswin Natarajan, Larysa Patskovska, Samantha Nyovanie, Bishnu Joshi, Benjamin Morin, Christine Brittsan, Olivia Huber, Samuel Gordon, Xavier Michelet, Florian Schmitzberger, Robert B. Stein, Mark A. Findeis, Andy Hurwitz, Marc Van Dijk, Jennifer S. Buell, Dennis Underwood, Michelle Krogsgaard
Altered protein phosphorylation in cancer cells often leads to surface presentation of phosphopeptide neoantigens. However, their role in cancer immunogenicity remains unclear. Here we describe a mechanism by which an HLA-B*0702-specific acute myeloi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86bb850ac390b9d0dcf033a5b7a2314e
https://doi.org/10.21203/rs.3.rs-2327641/v1
https://doi.org/10.21203/rs.3.rs-2327641/v1
Provides detailed clinical guidance on the management of ulcerative colitis by disease severity. Clinical presentation and diagnosis criteria are presented along with epidemiology, etiopathogenesis and environmental risk factors. The book contains th
Autor:
Anthony Sferruzza, Henry J. Pieniaszek, Dietmar A. Seiffert, Gregory F Hollis, Robert N. Daly, Donna L. Pedicord, Robert B. Stein, Tsushung A. Hua, Andrew M. Stern, Debra Cromley, Cathy J. Kieras, William Ebling, Bokang He, Richard Wynn, Richard J. Rossi, Yu Chen Barrett, Jeffrey T. Billheimer
Publikováno v:
Blood. 101:58-63
Thrombocytopenia is a relatively common side effect observed during glycoprotein (GP) IIb/IIIa antagonist therapy. With the oral antagonist roxifiban, we observed thrombocytopenia, defined as 50% reduction of platelets over predose values or below 90
Autor:
Mitchell A. Lazar, Robert B. Stein, Thomas A. Judge, Linda B. Hurd, Julius J. Deren, James D. Lewis, Sue A. Keilbaugh, Emma E. Furth, E.J Demissie, Gary R. Lichtenstein, Chinyu G. Su, Gary D. Wu, Franz Fogt
Publikováno v:
The American Journal of Gastroenterology. 96:3323-3328
OBJECTIVES: Previous research has demonstrated that ligands for the γ subtype of peroxisome proliferator-activated receptors (PPARs) reduce inflammation in two different murine models of colitis. This study was designed to examine the potential effi
Publikováno v:
American Journal of Gastroenterology. 96:1977-1997
Crohn’s disease and ulcerative colitis are two idiopathic inflammatory disorders of the GI tract. Manifestations of disease can be severe and lead to long term therapy with a variety of medications and/or surgery. Standard medical therapy consists
Autor:
Robert B. Stein, Gary R. Lichtenstein
Publikováno v:
Surgical Clinics of North America. 81:71-101
Crohn's disease is an inflammatory disorder of the bowel of unknown cause. Crohn's disease seems to result from stimulation of the intestinal immune cascade in genetically susceptible individuals. Although the specific antigen perpetuating this infla