Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Robert B. Rosenblatt"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Non-ablative ultrasound (US)-based techniques to improve targeted tropism of systemically infused cell therapies, particularly mesenchymal stromal cell (MSC), have gained attention in recent years. Mechanotransduction following targeted US sonication
Externí odkaz:
https://doaj.org/article/6483e646f86e4e5a9d8813bb709c3322
Publikováno v:
Theranostics
Mechanical forces from non-ablative pulsed focused ultrasound (pFUS) generate pro-inflammatory tumor microenvironments (TME), marked by increased cytokines, chemokines, and trophic factors, as well as immune cell infiltration and reduced tumor growth
Publikováno v:
Journal of Cellular and Molecular Medicine
Image‐guided pulsed focused ultrasound (pFUS) is a non‐invasive technique that can increase tropism of intravenously (IV)‐infused mesenchymal stromal cells (MSC) to sonicated tissues. MSC have shown promise for cardiac regenerative medicine str
Autor:
Parwathy Chandran, Robert B. Rosenblatt, Omer Aydin, Scott R. Burks, Lauren E. Tomlinson, Gadi Cohen, Joseph A. Frank, Rebecca M. Lorsung
Publikováno v:
Cancers, Vol 13, Iss 1546, p 1546 (2021)
Cancers
Volume 13
Issue 7
Cancers
Volume 13
Issue 7
Simple Summary This study provides a conceptual overview correlating temporal changes in the tumor immune-microenvironment (TIME) to the non-ablative pulse focused ultrasound (pFUS) in two different types of tumors. The pFUS-induced immunomodulation
Autor:
Joseph A. Frank, Gadi Cohen, Robert B. Rosenblatt, Scott R. Burks, Rebecca M. Lorsung, Lauren E. Tomlinson, Parwathy Chandran
Publikováno v:
Cancer Research. 81:2790-2790
Various cellular and biological immunotherapies have revolutionized the treatment of human malignancies by augmenting endogenous immune responses within the tumor microenvironment (TME). Although non-ablative pulsed-FUS (pFUS) has received less atten
Publikováno v:
Cancer Research. 80:3577-3577
Non-ablative pulsed focused ultrasound (pFUS) has shown promise as an immunomodulatory anti-cancer therapeutic. While largely nondestructive to tissues compared ablative ultrasound, pFUS can generate anti-tumor molecular microenvironments and enhance