Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Robert B. Rebhun"'
Autor:
Aryana M. Razmara, Alicia A. Gingrich, Christine M. Toedebusch, Robert B. Rebhun, William J. Murphy, Michael S. Kent, Robert J. Canter
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
The field of cancer immunology has seen a meteoric rise in interest and application due to the discovery of immunotherapies that target immune cells, often leading to dramatic anti-tumor effects. However, successful cellular immunotherapy for solid t
Externí odkaz:
https://doaj.org/article/1d5aeb038c354764ab226468ad278eb5
Publikováno v:
Veterinary Medicine and Science, Vol 8, Iss 3, Pp 966-981 (2022)
Abstract Background The use of fenbendazole (FBZ) in terminal cancer patients has recently increased, as anthelminthic drugs, such as FBZ and benzimidazole, exhibit anti‐tubulin effects in tumour cells. Objectives The present study evaluated the in
Externí odkaz:
https://doaj.org/article/951bc0c7b05d4e67a9e7d6d541eb08a1
Autor:
Kara T. Kleber, Khurshid R. Iranpur, Lauren M. Perry, Sylvia M. Cruz, Aryana M. Razmara, William T. N. Culp, Michael S. Kent, Jonathan A. Eisen, Robert B. Rebhun, Robert J. Canter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The microbiome has clearly been established as a cutting-edge field in tumor immunology and immunotherapy. Growing evidence supports the role of the microbiome in immune surveillance, self-tolerance, and response to immune checkpoint inhibitors such
Externí odkaz:
https://doaj.org/article/d49176b5b5bc4a278c3941ab0c484e7f
Autor:
Sean J. Judge, Joshua D. Bloomstein, Cyrus J. Sholevar, Morgan A. Darrow, Kevin M. Stoffel, Logan V. Vick, Cordelia Dunai, Sylvia M. Cruz, Aryana M. Razmara, Arta M. Monjazeb, Robert B. Rebhun, William J. Murphy, Robert J. Canter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeClinical successes using current T-cell based immunotherapies have been limited in soft tissue sarcomas (STS), while pre-clinical studies have shown evidence of natural killer (NK) cell activity. Since tumor immune infiltration, especially tum
Externí odkaz:
https://doaj.org/article/9ec99ada9f4e4f46aeaeab1be4c9ae38
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 5, Pp 2048-2055 (2020)
Abstract Background Azotemia occurs in cats administered doxorubicin, but risk factors have not been explored. Objective To determine incidence of progressive increases in serum creatinine concentration in cats with cancer receiving doxorubicin in si
Externí odkaz:
https://doaj.org/article/0b990b15822b46d0bebdaa6bd3a68dfc
Autor:
Maureen A. Griffin, William T. N. Culp, Michelle A. Giuffrida, Peter Ellis, Joanne Tuohy, James A. Perry, Allison Gedney, Cassie N. Lux, Milan Milovancev, Mandy L. Wallace, Jonathan Hash, Kyle Mathews, Julius M. Liptak, Laura E. Selmic, Ameet Singh, Carrie A. Palm, Ingrid M. Balsa, Philipp D. Mayhew, Michele A. Steffey, Robert B. Rebhun, Jenna H. Burton, Michael S. Kent
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 1, Pp 274-282 (2020)
Abstract Background Lower urinary tract transitional cell carcinoma (TCC) is an important but rarely described disease of cats. Objectives To report the clinical characteristics, treatments, and outcomes in a cohort of cats with lower urinary tract T
Externí odkaz:
https://doaj.org/article/3ec47d04213d4d9eb2109be36a77ab2c
Autor:
Ellen E. Sparger, Hong Chang, Ning Chin, Robert B. Rebhun, Sita S. Withers, Hung Kieu, Robert J. Canter, Arta M. Monjazeb, Michael S. Kent
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Investigation of canine T cell immunophenotypes in canine melanomas as prognostic biomarkers for disease progression or predictive biomarkers for targeted immunotherapeutics remains in preliminary stages. We aimed to examine T cell phenotypes and fun
Externí odkaz:
https://doaj.org/article/0cfee634520c4c68a85e229019c24a1f
Autor:
Aryana M. Razmara, Sean J. Judge, Alicia A. Gingrich, Sylvia M. Cruz, William T. N. Culp, Michael S. Kent, Robert B. Rebhun, Robert J. Canter
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Metastatic osteosarcoma has a bleak prognosis in both humans and dogs, and there have been minimal therapeutic advances in recent decades to improve outcomes. Naturally occurring osteosarcoma in dogs is shown to be a highly suitable model for human o
Externí odkaz:
https://doaj.org/article/0bd5c69fb3ea4ae58b877a3761fa8741
Autor:
Alicia A. Gingrich, Taylor E. Reiter, Sean J. Judge, Daniel York, Mio Yanagisawa, Aryana Razmara, Ian Sturgill, Ugur Nur Basmaci, Rachel V. Brady, Kevin Stoffel, William J. Murphy, Robert B. Rebhun, C. Titus Brown, Robert J. Canter
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are key effectors of the innate immune system, but major differences between human and murine NK cells have impeded translation. Outbred dogs offer an important link for studies of NK biology and immunotherapy. We analyzed g
Externí odkaz:
https://doaj.org/article/d91ccafa84ab4e79b697999b7b13c921
Autor:
Sami Al-Nadaf, Robert B. Rebhun, Kaitlin M. Curran, Rachel O. Venable, Katherine A. Skorupski, Jennifer L. Willcox, Jenna H. Burton
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-8 (2018)
Abstract Background A doxorubicin (DOX)-based chemotherapy protocol, CHOP, is the most effective treatment for canine high-grade B-cell lymphoma; however, the cost and time requirements associated with this protocol are not feasible for many pet owne
Externí odkaz:
https://doaj.org/article/40e72e53425e447e93c72d615b5c02a3