Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert B. Naso"'
Autor:
Robert B. Naso, Ali Fattom, Huan-Ming Chen, Kishna Kalicharran, Michal Minczuk, Ning Zhang, Herbert Schmitz, Piotr P. Stepien, Verena Koch, Ramachandra S. Hosmane, Peter Borowski
Publikováno v:
Journal of Medicinal Chemistry. 46:4776-4789
A series of ring-expanded ("fat") nucleoside analogues (RENs) containing the 6-aminoimidazo[4,5-e][1,3]diazepine-4,8-dione ring system have been synthesized and screened for inhibition of NTPase/helicase of the West Nile Virus (WNV). To assess the se
Autor:
Brent E. Korba, Ramachandra S. Hosmane, Earl R. Kern, Ramesh K. Sood, Ali Fattom, Vishweshwar S. Bhadti, Robert B. Naso, Huan-Ming Chen
Publikováno v:
Antiviral Research. 53:159-164
Novel ring-expanded nucleoside (REN) analogs (1-3) containing 5:7 fused ring systems as the heterocyclic base were found to be potent and selective inhibitors of hepatitis B virus (HBV) replication in cultured human hepatoblastoma 2.2.15 cells. The m
Autor:
Ali Ibrahim Fattom, Robert B. Naso
Publikováno v:
Advances in Renal Replacement Therapy. 3:302-308
Staphylococcus aureus infections are a major cause of morbidity in both hemodialysis and peritoneal dialysis patients. The availability of a safe and effective protective vaccine would be of great benefit to these patients, but attempts at using vacc
Publikováno v:
Drug Discovery Today. 1:381-387
The conjugation of polysaccharides to carrier proteins generally enhances polysaccharide immunogenicity and renders the immune response T-cell dependent. Such enhancement of immunogenicity has made the use of conjugate vaccines possible in population
Publikováno v:
Infection and Immunity. 64:1659-1665
The efficacy of capsular polysaccharide (CP)-specific antibodies elicited by active immunization with vaccines composed of Staphylococcus aureus types 5 and 8 CP linked to Pseudomonas aeruginosa exoprotein A or with immune immunoglobulin G (I-IgG) ob
Autor:
Yun Hee Cho, Abbas Hawwari, Sara E. Shepherd, Robert B. Naso, Amy Burns, Scott Winston, Richard T. Coughlin, Xiuru Li, Ali Ibrahim Fattom
Publikováno v:
Vaccine. 13:1288-1293
Conjugate vaccines were prepared with S. aureus type 8 capsular polysaccharide (CP) using three carrier proteins: Pseudomonas aeruginosa exotoxin A (ETA), a non-toxic recombinant ETA (rEPA), and diphtheria toxoid (DTd). Adipic acid dihydrazide (ADH)
Publikováno v:
American Journal of Health-System Pharmacy. 49:1455-1458
The stability, potency, and preservative effectiveness of two dilutions of epoetin alfa containing a bacteriostatic diluent were studied. Epoetin alfa 10,000 units/mL in single-use vials was diluted 1:1 and 1:1.5 with bacteriostatic 0.9% sodium chlor
Publikováno v:
American heart journal. 147(4)
Background Staphylococcus aureus , the first or second most common pathogen isolated from patients, is capsulated; there are at least 12 capsular types, and types 5 and 8 comprise approximately 85% of blood. Types 5 and 8, composed of a trisaccharide
Publikováno v:
Vaccine. 22(7)
Staphylococcus aureus is the most common nosocomial pathogen and is responsible for approximately one-third of hospital-acquired bacteremias. The emergence of strains with multidrug resistance, including resistance to vancomycin, the antibiotic of la
Autor:
Peter Borowski, Herbert Schmitz, Ali Ibrahim Fattom, Ramachandra S. Hosmane, Verena Koch, Vishweshwar S. Bhadti, Huan-Ming Chen, Ching-Len Liao, Maria Bretner, Robert B. Naso, Ning Zhang
Publikováno v:
Journal of medicinal chemistry. 46(19)
A series of ring-expanded ("fat") heterocycles, nucleoside and nucleotide analogues (RENs) containing the imidazo[4,5-e][1,3]diazepine ring system (9, 14, 15, 18, 24-26, 28, 31, and 33) and imidazo[4,5-e][1,2,4]triazepine ring systems (30b, 30c, 32,