Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Robert B. Macgregor"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Of all methods exercised in modern molecular biology, modification of cellular properties through the introduction or removal of nucleic acids is one of the most fundamental. As such, several methods have arisen to promote this process; thes
Externí odkaz:
https://doaj.org/article/87568a22fd7f44459752e89120d61dd8
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e18318- (2023)
Multidrug nanomedicine is an effective therapeutic approach for the treatment of chronic diseases and cancers. However, co-encapsulation and release of drug combination at a fixed ratio by nanoparticles, particularly for long acting ocular formulatio
Externí odkaz:
https://doaj.org/article/63a5e94fd2a1486d890f4ee54fab985a
Autor:
Xinyang Li, Chen Liang, Yexuan Guo, Jing Su, Xi Chen, Robert B. Macgregor, Rui Xue Zhang, Hong Yan
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1235 (2023)
Posterior capsule opacification (PCO) remains the most common cause of vision loss post cataract surgery. The clinical management of PCO formation is limited to either physical impedance of residual lens epithelial cells (LECs) by implantation of spe
Externí odkaz:
https://doaj.org/article/55d5016a5aab4bf7813e53ca99d89106
Publikováno v:
Life, Vol 12, Iss 5, p 765 (2022)
The G-quadruplex (GQ), a tetrahelix formed by guanine-rich nucleic acid sequences, is a potential drug target for several diseases. Monomolecular GQs are stabilized by guanine tetrads and non-guanine regions that form loops. Hydrostatic pressure dest
Externí odkaz:
https://doaj.org/article/7b8a0e4eb7f24ccea6ef361402cdda7c
Publikováno v:
Biology, Vol 10, Iss 8, p 813 (2021)
Four-stranded non-canonical DNA structures including G-quadruplexes and i-motifs have been found in the genome and are thought to be involved in regulation of biological function. These structures have been implicated in telomere biology, genomic ins
Externí odkaz:
https://doaj.org/article/33cceb8a60cf4c3c865dbeb5ffd7941b
Autor:
Hasan Y. Alniss, Chen Chu, Wafaa S. Ramadan, Yousef A. Msallam, Vunnam Srinivasulu, Raafat El-Awady, Robert B. Macgregor, Taleb H. Al-Tel
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1867:130347
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35785181763b7743a1adc01360bbf0d4
https://doi.org/10.1016/j.bbagen.2023.130347
https://doi.org/10.1016/j.bbagen.2023.130347
Autor:
David N. Dubins, Lutan Liu, Nabeel Tariq, Takuma Kume, Lily Scott, Robert B. Macgregor, Tigran V. Chalikian
Publikováno v:
The Journal of Physical Chemistry B. 125:7406-7416
The kinetic and thermodynamic stabilities of G-quadruplex structures have been extensively studied. In contrast, systematic investigations of the volumetric properties of G-quadruplexes determining their pressure stability are still relatively scarce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70535d87b58b0c0cde38fa2ca305223
https://doi.org/10.1021/acs.jpcb.1c04075
https://doi.org/10.1021/acs.jpcb.1c04075
Publikováno v:
Biophysical Chemistry. :107043
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac6501837f813082fa156c014f0839c
https://doi.org/10.1016/j.bpc.2023.107043
https://doi.org/10.1016/j.bpc.2023.107043
Autor:
Jaiwoo Lee, Quoc-Viet Le, Seungbeom Ko, Sungtaek Kang, Robert B. Macgregor, Gayong Shim, Yu-Kyoung Oh
Publikováno v:
Biomaterials. 289
We report polymeric DNA-supported gold clusters that achieve interparticle plasmon-coupling, generate immunotherapeutic effects at the tumor tissue, but decluster in the bloodstream. As immunostimulating DNA, we used polyCpG DNA, which could act as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8108a3da537eb8762659524a7f7a02b2
https://pubmed.ncbi.nlm.nih.gov/36058030
https://pubmed.ncbi.nlm.nih.gov/36058030
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed2492d994c550fdef8832a7c130affe
https://doi.org/10.1007/978-981-16-1313-5_3-1
https://doi.org/10.1007/978-981-16-1313-5_3-1
