Zobrazeno 1 - 10 of 67 pro vyhledávání: '"Robert B. Low"'
1
Functional Effects of the Hypertrophic Cardiomyopathy R403Q Mutation Are Different in an α- or β-Myosin Heavy Chain Backbone
Autor: Arthur S. Rovner, Susan Lowey, James Gulick, Leanne M. Lesko, Robert B. Low, Sheryl L. White, Mercedes Rincon, Alex R. Hodges, Jeffrey Robbins
Publikováno v: Journal of Biological Chemistry. 283:20579-20589
The R403Q mutation in the beta-myosin heavy chain (MHC) was the first mutation to be linked to familial hypertrophic cardiomyopathy (FHC), a primary disease of heart muscle. The initial studies with R403Q myosin, isolated from biopsies of patients, s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769c613f40c8e4797d624bfe70cd6944
https://doi.org/10.1074/jbc.m800554200
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2
(+)Insert smooth muscle myosin heavy chain (SM-B): From single molecule to human
Autor: Robert B. Low, Anne-Marie Lauzon, Renaud Léguillette
Publikováno v: The International Journal of Biochemistry & Cell Biology. 38:1862-1874
In smooth muscle, alternative mRNA splicing of a single gene produces four myosin heavy chain (SMMHC) isoforms. Two of these isoforms differ by the presence [(+)insert] or absence [(-)insert] of a seven amino acid insert in the motor domain. This ins
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa593f978be5f7954eee3d928faf01a8
https://doi.org/10.1016/j.biocel.2006.03.014
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3
Microvessel precursor smooth muscle cells express head-inserted smooth muscle myosin heavy chain (SM-B) isoform in hyperoxic
Autor: Margaretha Jacobson, Robert B. Low, Wolfgang Steudel, Rosemary Jones, Sheryl L. White
Publikováno v: Cell and Tissue Research. 295:453-465
The present study analyzes smooth muscle myosin heavy chain (SMMHC) expression as lung microvascular precursor smooth muscle cells (PSMCs), cells derived from fibroblasts and intermediate cells (immature SMCs), acquire a smooth muscle phenotype in an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5949843ac69ee4bc9919b9cdf5c7753c
https://doi.org/10.1007/s004410051251
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5
Increased collagen synthesis and decreased collagen degradation in right ventricular hypertrophy induced by pressure overload
Autor: Geoffrey J. Laurent, Robert B. Low, Suzanne Rhodes, William S. Stirewalt, Jill E. Bishop
Publikováno v: Cardiovascular Research. 28:1581-1585
Objective: The aim was to examine the effect of pressure overload in rabbits on ventricular collagen metabolism and procollagen gene expression. Methods: Right ventricular hypertrophy was induced by banding the pulmonary artery such that the diameter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd2a1b64e0e1097b2a0852704e0cb33
https://doi.org/10.1093/cvr/28.10.1581
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6
Myosin Isoform Expression in Developing and Remodeling Rat Lung
Autor: Janet Woodcock-Mitchell, Robert B. Low, John D. Mitchell, William S. Stirewalt, Muthu Periasamy, Sheryl L. White
Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 8:617-625
The tissue distribution of myosin isoforms was examined in developing smooth muscle of rat lung. Antisera employed included a general smooth muscle myosin antibody (aSMMG) and two smooth muscle myosin isoform specific antisera (aSM1 and aSM2). In the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60546aede05b73fad560360ab2b7d4d
https://doi.org/10.1165/ajrcmb/8.6.617
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7
Serum and Bronchoalveolar Lavage of N-Terminal Type III Procollagen Peptides in Idiopathic Pulmonary Fibrosis
Autor: Talmadge E. King, Pamela M. Vacek, Robert B. Low, Michael S. Giancola, Gerald S. Davis, Jane Chapitis
Publikováno v: American Review of Respiratory Disease. 146:701-706
Collagen deposition is a prime determinant of clinical course in idiopathic pulmonary fibrosis (IPF). Identification of a marker of connective tissue metabolism would significantly enhance the ability to stage the disease and monitor the course of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701d56706bbedcfbf10a039447ce4e29
https://doi.org/10.1164/ajrccm/146.3.701
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8
Serum Type III Procollagen N-Terminal Peptide in Coal Miners
Autor: Robert B. Low, Paul J. A. Borm, Yvonne M. W. Janssen, Michael S. Giancola, Pamela M. Vacek, John J. M. Engelen
Publikováno v: Experimental Lung Research. 18:1-8
Health surveillance of workers exposed to fibrogenic agents ideally should identify individuals at risk or detect pulmonary fibrosis in preclinical stages. We investigated serum procollagen type III N-terminal peptide (PIIIP) in several groups of act
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f249fbe3031b8aac56f0a076de17dfb
https://doi.org/10.3109/01902149209020646
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10
Alpha smooth muscle actin expression in developing and adult human lung
Autor: Robert B. Low, John J. Mitchell, Janet Woodcock-Mitchell, Kevin O. Leslie
Publikováno v: Differentiation. 44:143-149
Myofibroblast-like cells containing smooth muscle actin have been identified in lung injury and repair. These cells differ from typical smooth muscle cells by architectural configuration, location and lack of smooth muscle myosin. Their progenitors a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6df6d1977bfe698619119660dc5fd35
https://doi.org/10.1111/j.1432-0436.1990.tb00547.x
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