Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Robert B. Crawford"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Innate-like B cells (ILBs) are a heterogeneous population B cells which participate in innate and adaptive immune responses. This diverse subset of B cells is characterized by the expression of CD5 and has been shown to secrete high levels of immunog
Externí odkaz:
https://doaj.org/article/5660827bccf64d4ea97f9b8727080b34
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Xenobiotic-mediated activation of the aryl hydrocarbon receptor (AHR) is immunotoxic in a number of immune cell types, with the B cell being a well-established sensitive target. Recent advances have provided evidence that the B cell repertoire is a h
Externí odkaz:
https://doaj.org/article/7769771e5e904e0bb3abea3b549ac8fb
Autor:
Robert D. Stedtfeld, Benli Chai, Robert B. Crawford, Tiffany M. Stedtfeld, Maggie R. Williams, Shao Xiangwen, Tomomi Kuwahara, James R. Cole, Norbert E. Kaminski, James M. Tiedje, Syed A. Hashsham
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Environmental toxicants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an aryl hydrocarbon receptor (AhR), are known to induce host toxicity and structural shifts in the gut microbiota. Key bacterial populations with similar or opposing function
Externí odkaz:
https://doaj.org/article/79683224aaae476997103cbe375fdcec
Autor:
Lance K. Blevins, Anthony P. Bach, Robert B. Crawford, Jiajun Zhou, Joseph E. Henriquez, Michael D. Rizzo, Sera Sermet, D.M. Isha Olive Khan, Helen Turner, Andrea L. Small-Howard, Norbert E. Kaminski
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 170
Cannabis is well established as possessing immune modulating activity. The objective of this study was to evaluate the anti-inflammatory properties of selected cannabis-derived terpenes and cannabinoids. Based on their activity in cannabis-chemovar s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a8cd2e3c5149c4d855b05cb36a2b14
https://pubmed.ncbi.nlm.nih.gov/36228902
https://pubmed.ncbi.nlm.nih.gov/36228902
Publikováno v:
Journal of Leukocyte Biology. 110:123-140
Translocator protein 18 kDa (TSPO) is a well-known outer mitochondrial membrane protein and it is widely used as a biomarker of neuroinflammation and brain injury. Although it is thought that TSPO plays key roles in a multitude of host cell functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d13f4c032fd84e3b8e601db2515b6d2
https://doi.org/10.1002/jlb.3a1219-729rr
https://doi.org/10.1002/jlb.3a1219-729rr
Autor:
Norbert E. Kaminski, Robert B. Crawford, Michael D. Rizzo, Anthony Bach, Lance K. Blevins, Joseph E. Henriquez
Publikováno v:
J Neuroimmune Pharmacol
HIV infection affects an estimated 38 million people. Approximately 50% of HIV patients exhibit neurocognitive dysfunction termed HIV-Associated Neurocognitive Disorder (HAND). HAND is a consequence of chronic low-level neuroinflammation due to HIV e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f67cd1e0e83170b9c2623c401ec5a8a
https://doi.org/10.1007/s11481-020-09918-7
https://doi.org/10.1007/s11481-020-09918-7
Autor:
Karina M Matos-Fernandez, Robert B. Crawford, Anthony Bach, Joseph E. Henriquez, Norbert E. Kaminski
Publikováno v:
J Neuroimmune Pharmacol
CD8+ T cells can contribute to neuroinflammation by secretion of inflammatory cytokines like interferon γ (IFNγ) and tumor necrosis factor α (TNFα). Astrocytes, a glial cell in the brain, can be stimulated by IFNγ and TNFα to secrete the inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd0985c3cc51acbf81e48e7a23e7274
https://doi.org/10.1007/s11481-020-09912-z
https://doi.org/10.1007/s11481-020-09912-z
Autor:
Robert B. Crawford, Shao Ju Chien, Manish Neupane, Feng Rong Chuang, Te Chuan Chen, Chia-Cheng Chang, Norbert E. Kaminski
Publikováno v:
Stem Cells and Development. 28:1424-1433
Dome formation can occur in cultured tubular epithelial cells originating from various tissues, including the mammary gland and the kidney. The isolation and characterization of normal kidney epithelial stem cells that give rise to dome-forming tubul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85f1e07403ecffae3f057dcd4636bfd
https://doi.org/10.1089/scd.2019.0049
https://doi.org/10.1089/scd.2019.0049
Autor:
Andrea Amalfitano, Robert B. Crawford, Michael D. Rizzo, Sera Sermet, Anthony Bach, Norbert E. Kaminski
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 371:191-201
Cannabis is widely used in the United States, with an estimated prevalence of 9.5%. Certain cannabinoids in Cannabis sativa, Δ9-tetrahydrocannabinol (THC) in particular, possess immune-modulating and anti-inflammatory activity. Depending on the cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c62e08978f55f0bf75e50c17ac9f1627
https://doi.org/10.1124/jpet.119.260661
https://doi.org/10.1124/jpet.119.260661
Publikováno v:
Toxicol Appl Pharmacol
Plasmacytoid dendritic cells (pDC) compose 0.2–0.5% of circulating leukocytes but play a significant role in mounting host immune responses. Elevated and chronic activation of pDC are implicated in autoimmune disease like systemic lupus erythematos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50ba2ba58d2b5e1460a4465e7f1bb44
https://doi.org/10.1016/j.taap.2019.02.013
https://doi.org/10.1016/j.taap.2019.02.013