Výsledky vyhledávání - "Robert B Kleiman"

False Negative ECG Device Results May Increase the Risk of Adverse Events in Clinical Oncology Trials

Publikováno v: Therapeutic innovationregulatory science. 56(4)

Background Sites participating in clinical trials may not have the expertise and infrastructure to accurately measure cardiac intervals on 12-lead ECGs and rely heavily on the automated ECG device generated results for clinical decision-making. Metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79982d476965b128be7e37063d84f4f6
https://pubmed.ncbi.nlm.nih.gov/35471562

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Thorough QT/QTc Evaluation of the Cardiac Safety of Enarodustat (JTZ-951), an Oral Erythropoiesis-Stimulating Agent, in Healthy Adults

Autor: Qingtao Mike Huang, Ryosuke Koretomo, Rui Zhuo, Robert B Kleiman, Hiroyuki Yamada, Sudhakar M. Pai

Publikováno v: Clinical pharmacology in drug developmentReferences. 10(8)

This study evaluated the effect of enarodustat on cardiac repolarization in healthy subjects. Enarodustat (20 and 150 mg [supratherapeutic dose]), placebo, and moxifloxacin (positive control, 400 mg) were administered orally to males and females (N =

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8f84e807d584da0b15829a276f59c1
https://pubmed.ncbi.nlm.nih.gov/34159762

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Comparison of Simultaneous Versus Sequential Defibrillation Pulsing Techniques Using a Nonthoracotomy System

Autor: Belinda T. Flores, Henry H. Hsia, Francis E. Marchlinski, Robert B. Kleiman

Publikováno v: Pacing and Clinical Electrophysiology. 17:1222-1230

The defibrillation threshold (DFT) using simultaneous (SIML) versus sequential (SEQ) pathways for shock delivery was compared in 16 patients with an implanted cardioverter defibrillator. All patients had three-lead nonthoracotomy systems (NTL) using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd64984717f2bcd65cd5453a0c40f311
https://doi.org/10.1111/j.1540-8159.1994.tb01489.x

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Failure of Defibrillator Paddle as Mimic for Subcutaneous Patch Lead During Nonthoracotomy Implantable Cardioverter Defibrillator Lead Configuration Assessment

Autor: Roman T. Pachulski, Robert B. Kleiman, Mark E. Josephson, Francis E. Marchlinski

Publikováno v: Pacing and Clinical Electrophysiology. 15:1253-1257

It is a common, although virtually unsubstantiated, practice to assess the efficacy of nonthoracotomy lead systems for implantable cardioverter defibrillators using a defibrillator paddle as mimic for the subcutaneous patch lead. We report a case in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21542e8def1890d61a7c69baabe8247
https://doi.org/10.1111/j.1540-8159.1992.tb03136.x

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Effectiveness of noninvasive programmed stimulation for initiating ventricular tachyarrhythmias in patients with third-generation implantable cardioverter defibrillators

Autor: Bruce G. Hook, Francis E. Marchlinski, David J. Callans, Robert B. Kleiman

Publikováno v: Pacing and clinical electrophysiology : PACE. 17(9)

Previous generations of implantable cardioverter defibrillators (ICDs) required invasive electrophysiological testing to assess defibrillator function. Newer third-generation ICDs include the capability for performing noninvasive programmed stimulati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0aa42d42ae1313d8993901a930bc26
https://pubmed.ncbi.nlm.nih.gov/7991416

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Implantable cardioverter-defibrillator therapy in the absence of significant symptoms. Rhythm diagnosis and management aided by stored electrogram analysis

Autor: David J. Callans, Bruce G. Hook, Belinda T. Flores, Francis E. Marchlinski, Robert B. Kleiman

Publikováno v: Circulation. 87(6)

BACKGROUND This report describes the value of stored ventricular electrogram analysis in the diagnosis and management of patients experiencing minimal or no symptoms before implantable cardioverter-defibrillator (ICD) therapy. METHODS AND RESULTS The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23609a8ccbf27b13979a2760d4d7089c
https://pubmed.ncbi.nlm.nih.gov/8504502

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Endocardial mapping during sinus rhythm in patients with coronary artery disease and nonsustained ventricular tachycardia

Autor: Robert B. Kleiman, Alfred E. Buxton, Kindwall Ke, Mark E. Josephson

Publikováno v: The American journal of cardiology. 71(8)

Programmed stimulation in patients with nonsustained ventricular tachycardia (VT) and coronary artery disease (CAD) induces sustained VT in 30 to 50% of patients. The presence of inducible, sustained VT identifies patients at high risk for sudden dea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7771fb241af865ac3182df480963fc00
https://pubmed.ncbi.nlm.nih.gov/8447267

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Acute and chronic cycle length dependent increase in ventricular pacing threshold

Autor: David J. Callans, Belinda T. Flores, Francis E. Marchlinski, Robert B. Kleiman, Richard L. Perlman, Bruce G. Hook, Michael S. Hanna

Publikováno v: Pacing and clinical electrophysiology : PACE. 15(10 Pt 1)

Several factors have been shown to influence ventricular pacing threshold in humans, including pacing lead location (endocardial vs epicardial), lead maturation, and antiarrhythmic agents. To determine whether ventricular pacing rate has a significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c93e629911cd74c9f93e2e3ca01476a
https://pubmed.ncbi.nlm.nih.gov/1383954

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