Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Robert Bähring"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191911 (2018)
Kv4.2 channels mediate a subthreshold-activating somatodendritic A-type current (ISA) in hippocampal neurons. We examined the role of accessory Kv channel interacting protein (KChIP) binding in somatodendritic surface expression and activity-dependen
Externí odkaz:
https://doaj.org/article/4f1f074ef64644e496d1d6d1aaeec920
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0171213 (2017)
The transient outward current (Ito) in cardiomyocytes is largely mediated by Kv4 channels associated with Kv Channel Interacting Protein 2 (KChIP2). A knockout model has documented the critical role of KChIP2 in Ito expression. The present study was
Externí odkaz:
https://doaj.org/article/f87a0d15abc0485ca38deb6a429bbb7a
Autor:
Daniel Minge, Robert Bähring
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26664 (2011)
Pathophysiological remodeling processes at an early stage of an acquired epilepsy are critical but not well understood. Therefore, we examined acute changes in action potential (AP) dynamics immediately following status epilepticus (SE) in mice. SE w
Externí odkaz:
https://doaj.org/article/1bfd114067a14cb2b95d926ce1eb1f60
KCND2 variants associated with global developmental delay differentially impair Kv4.2 channel gating
Autor:
Claudia Schob, Heidi L. Rehm, Johannes R. Lemke, Brianna Pruniski, Yongqiang Zhang, Stefan Kindler, Claudia A. L. Ruivenkamp, Tiffani L McDonough, Arie van Haeringen, Ulrike B. S. Hedrich, Robert Bähring, Grace E. VanNoy, Hanno J. Bolz, Emily Bryant, Trine Prescott, Holger Lerche, Georgios Tachtsidis, Kristian Tveten, Heather M. McLaughlin, Mahmoud Koko, Thorsten Gerstner, Stephanie DiTroia, U. Zechner
Publikováno v:
Human Molecular Genetics, 30(23), 2300-2314. OXFORD UNIV PRESS
Hum Mol Genet
Hum Mol Genet
Here, we report on six unrelated individuals, all presenting with early-onset global developmental delay, associated with impaired motor, speech and cognitive development, partly with developmental epileptic encephalopathy and physical dysmorphisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8438641d24be9f024344f14a1dc669a1
https://hdl.handle.net/1887/3257107
https://hdl.handle.net/1887/3257107
Publikováno v:
J Biol Chem
Voltage-gated potassium (Kv) channels of the Kv4 subfamily associate with Kv channel–interacting proteins (KChIPs), which leads to enhanced surface expression and shapes the inactivation gating of these channels. KChIP3 has been reported to also in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20df05a2c4321baca43ad8d38cbf777
https://europepmc.org/articles/PMC7443505/
https://europepmc.org/articles/PMC7443505/
Autor:
Robert Bähring
Publikováno v:
Channels
Kv channel-interacting proteins (KChIPs) belong to the neuronal calcium sensor (NCS) family of Ca2+-binding EF-hand proteins. KChIPs constitute a group of specific auxiliary β-subunits for Kv4 channels, the molecular substrate of transient potassium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce40f396b1864afc5225493a817131ae
https://doi.org/10.1080/19336950.2018.1491243
https://doi.org/10.1080/19336950.2018.1491243
Autor:
Christiane Groen, Robert Bähring
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 469:1457-1470
The transient outward current (I to) in the human heart is mediated by Kv4.3 channels complexed with Kv channel interacting protein (KChIP) 2, a cytoplasmic Ca2+-binding EF-hand protein known to modulate Kv4.3 inactivation gating upon heterologous co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd6c35c20b018ac79cda2ece244ac60
https://doi.org/10.1007/s00424-017-2039-2
https://doi.org/10.1007/s00424-017-2039-2
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0171213 (2017)
PLoS ONE
PLoS ONE
The transient outward current (Ito) in cardiomyocytes is largely mediated by Kv4 channels associated with Kv Channel Interacting Protein 2 (KChIP2). A knockout model has documented the critical role of KChIP2 in Ito expression. The present study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c169c68739b7dd4e77be964afa51bff1
http://europepmc.org/articles/PMC5283746?pdf=render
http://europepmc.org/articles/PMC5283746?pdf=render
Autor:
Robert Bähring, Christiane K. Bauer
Publikováno v:
Advances in Physiology Education. 38:253-264
The generation and conduction of neuronal action potentials (APs) were the subjects of a cell physiology exercise for first-year medical students. In this activity, students demonstrated the all-or-none nature of AP generation, measured conduction ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218be4af3d1d91a26fa6c634e02e3e4f
https://doi.org/10.1152/advan.00137.2013
https://doi.org/10.1152/advan.00137.2013
Publikováno v:
Neuropharmacology. 63:1389-1403
We examined the effects of the sulfonylurea compound NS5806 on neuronal A-type channel function. Using whole-cell patch-clamp we studied the effects of NS5806 on the somatodendritic A-type current (ISA) in cultured hippocampal neurons and the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35ff847353e575c59db6cd10defa410
https://doi.org/10.1016/j.neuropharm.2012.08.017
https://doi.org/10.1016/j.neuropharm.2012.08.017