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Autor:
Leticia Sansores-Garcia, Kathleen M Gajewski, Robert Andrew Mills, Leen Van Huffel, Mardelle Atkins, Violaine Mottier-Pavie, Jana Mach, Weronika Kowalczyk, Jun Xie, Georg Halder, Gordon B. Mills
Publikováno v:
Proceedings of the National Academy of Sciences. 115:10684-10689
The Hippo tumor-suppressor pathway regulates organ growth, cell proliferation, and stem cell biology. Defects in Hippo signaling and hyperactivation of its downstream effectors-Yorkie (Yki) in Drosophila and YAP/TAZ in mammals-result in progenitor ce