Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert Amezquita"'
Autor:
Brian Rini, Mariangela Mariani, Alessandra di Pietro, Paul Nathan, Christian Kollmannsberger, Marc-Oliver Grimm, Martin H Voss, Bradley A McGregor, Mehmet A Bilen, Yoshihiko Tomita, Bo Huang, Robert Amezquita, Matthew Tucker, Yu-Wei Chen
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective We report post hoc analyses of efficacy with first-line avelumab plus axitinib or sunitinib according to baseline neutrophil-to-eosinophil ratio (NER) in patients with advanced renal cell carcinoma (aRCC) from the JAVELIN Renal 101 phase 3
Externí odkaz:
https://doaj.org/article/e21e585079dc450abadbe8a2b44d6e73
Autor:
Vladimir Makarov, Paul Nghiem, Jaehyuk Choi, Timothy A Chan, Kimberly S Smythe, Jean S Campbell, Robert H Pierce, Raphael Gottardo, Candice Church, David M Koelle, Thomas Pulliam, Natalie Longino, Song Y Park, Nadeem Riaz, Lichen Jing, Robert Amezquita
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Merkel cell carcinoma (MCC) often responds to PD-1 pathway blockade, regardless of tumor-viral status (~80% of cases driven by the Merkel cell polyomavirus (MCPyV)). Prior studies have characterized tumor-specific T cell responses to MCPyV
Externí odkaz:
https://doaj.org/article/5ad5aa1d8a2c41f09cc92ec9ecc890fa
Autor:
Kristen W. Cohen, Yuan Tian, Casey Thayer, Aaron Seese, Robert Amezquita, M. Juliana McElrath, Stephen C. De Rosa, Raphael Gottardo
Publikováno v:
The Journal of Immunology. 209:526-534
Ag-specific T cells play a critical role in responding to viral infections. In the RV144 HIV vaccine clinical trial, a rare subset of HIV-specific polyfunctional CD4+ T cells correlated with reduced risk of HIV-1 infection. Polyfunctional T cells are
Autor:
Andrew Nager, David Schaer, Rebecca Gallego, Eleanore Hendrickson, Sergei Timofeevski, Manqing Li, Allison Rohner, Ruth Seelige, Samuel Stoner, Christopher Dillon, Paulina Cuenca, Cinthia Jones, Sarah Firdaus, Robert Amezquita, Clifford Restaino, Derek Bartlett, Timothy Fisher
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Candice Church, Thomas Pulliam, Natalie Longino, Song Y Park, Kimberly S Smythe, Vladimir Makarov, Nadeem Riaz, Lichen Jing, Robert Amezquita, Jean S Campbell, Raphael Gottardo, Robert H Pierce, Jaehyuk Choi, Timothy A Chan, David M Koelle, Paul Nghiem
Publikováno v:
Journal for immunotherapy of cancer. 10(9)
BackgroundMerkel cell carcinoma (MCC) often responds to PD-1 pathway blockade, regardless of tumor-viral status (~80% of cases driven by the Merkel cell polyomavirus (MCPyV)). Prior studies have characterized tumor-specific T cell responses to MCPyV,
Publikováno v:
Nature methods. 17(6)
Publikováno v:
Cancer Immunology Research. 4:IA07-IA07
Activated T cells engage aerobic glycolysis and anabolic metabolism for growth, proliferation, and effector functions. In contrast, resting memory CD8 T cells depend less on high rates of glycolysis and more on fatty acid oxidation to persist, self-r