Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Robert Alun Saunders"'
Autor:
Michael Graz, Gareth J. S. Evans, James Stansall, Alastair Baker, Filipa V.M. Silva, Robert Alun Saunders, Mehkman S. Yusubov, Thomas Wirth, Weronika Michalska
Publikováno v:
European Journal of Organic Chemistry. 2018:2134-2137
A packed bed reactor with oxone has been employed for selective oxidations of sulfur compounds. Various sulfides containing different functional groups are efficiently oxidized to the corresponding sulfoxides without formation of sulfones or other si
Autor:
Robert Alun Saunders, Ilaria Pitotti, Alastair Baker, Thomas Wirth, Michael Graz, Gareth J. S. Evans
Publikováno v:
Journal of Flow Chemistry. 5:65-68
Rapid alkylations of thiols are performed in a packed-bed flow reactor where potassium carbonate acts as a heterogeneous base in anhydrous solvents at ambient temperature. The reaction also has a high efficiency as the removal of the solvent is the o
Autor:
Thomas Wirth, Sandra Kaul, Robert Alun Saunders, Alastair Baker, Gareth J. S. Evans, Michael Graz
Publikováno v:
Journal of Flow Chemistry. 3:118-121
Using mild conditions and short reaction times, symmetrical disulfides have been synthesized in flow chemistry using phase transfer catalysts to facilitate the substitution of organohalides with disodium disulfide. Also, the synthesis of symmetrical
Autor:
David Lloyd, Coralie Ode Millet, Joanne Cable, Gareth J. S. Evans, David R. Williams, Robert Alun Saunders, Catrin Ffion Williams
Publikováno v:
Experimental Parasitology. 127:490-499
Spironucleus is a genus of small, flagellated parasites, many of which can infect a wide range of vertebrates and are a significant problem in aquaculture. Following the ban on the use of metronidazole in food fish due to toxicity problems, no satisf
Publikováno v:
Journal of Fluorine Chemistry. 125:1291-1298
A model for the prediction of fluorophilicity based on the regression of experimental values for 93 organic molecules against molecular surface area descriptors has been constructed. The model is predictively accurate, with R 2 =0.94 and RMS=0.638. A
Publikováno v:
Journal of Physical Organic Chemistry. 17:431-438
Models of critical micelle concentration (CMC) using two separate methods, the linear free energy relationship of Abraham and a modified polar surface area approach, are reported. Individual models are developed for anionic, non-ionic and structurall
Publikováno v:
Journal of Fluorine Chemistry. 115:119-128
Linear free energy relation (LFER) models of the partition of 91 organic compounds between organic and fluorous solvents are presented. By reducing organic/fluorous partition to a sum of solvent–solute interaction terms we have developed accurate p
Publikováno v:
Journal of Physical Organic Chemistry. 14:612-617
Linear free energy relationship (LFER) methods were used to construct a model for the solubility of a species in supercritical CO2. The final model was based on 64 molecules and 782 data points, employing a modified version of the Abraham LFER equati
Publikováno v:
New Journal of Chemistry. 28:166
Modifications to the standard definition of polar surface area (PSA) are reported and tested against the octanol–water, chloroform–water and cyclohexane–water partition coefficients of 110 organic and drug-like molecules. It is shown that incre