Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Robert A. de Man"'
Autor:
Michiel S. Oerbekke, Robert A. de Man, Frederike G. I. van Vilsteren, Maarten W. Nijkamp, Eric Tjwa, Charlotte M. W. Gaasterland, Maarten J. van der Laan, Lotty Hooft
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract We aim to illustrate the role of complete and transparent reporting coupled with access to data sourced from published systematic reviews, especially assisting in the identification of evidence for subgroups within the context of a rare dise
Externí odkaz:
https://doaj.org/article/5291d8546b254862a053c84197d51f90
Autor:
Sylvia M. Brakenhoff, Heng Chi, Pieter Friederich, Michail Doukas, Caroline den Hoed, Hajo J. Flink, Robert J. de Knegt, Robert A. de Man
Publikováno v:
Case Reports in Gastroenterology, Vol 18, Iss 1, Pp 252-259 (2024)
Introduction: Emerging evidence suggests that long-term nucleos(t)ide analogue (NA) therapy can be ceased in a selective group of chronic hepatitis B (CHB). This is being gradually implemented in clinical practice. Case Presentation: A 68-year-old ma
Externí odkaz:
https://doaj.org/article/b5104e93061d4d369b3810d06033a46f
Autor:
Boris J. B. Beudeker, Rael Guha, Kalina Stoyanova, Jan N. M. IJzermans, Robert A. de Man, Dave Sprengers, Andre Boonstra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The incidence of hepatocellular carcinoma (HCC) in non-cirrhotic livers is rising significantly, but clear risk factors for screening remain elusive. This study sought to characterize non-cirrhotic HCC etiologies. HCC cases from 2009 to 2020
Externí odkaz:
https://doaj.org/article/9db4c47edbaf4f7eb508af6c03cccdda
Autor:
Diahann T. S. L. Jansen, Monique T. A. de Beijer, Robbie J. Luijten, Kitty Kwappenberg, Anna-Sophia Wiekmeijer, Amy L. Kessler, Roel F. A. Pieterman, Rachid Bouzid, Willem-Jan Krebber, Robert A. de Man, Cornelis J. M. Melief, Sonja I. Buschow
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTherapeutic vaccination based on synthetic long peptides (SLP®) containing both CD4+ and CD8+ T cell epitopes is a promising treatment strategy for chronic hepatitis B infection (cHBV).MethodsWe designed SLPs for three HBV proteins, HBcA
Externí odkaz:
https://doaj.org/article/42979833c13449608bd111357e727466
Autor:
Sylvia M. Brakenhoff, Robert J. de Knegt, Margo J.H. van Campenhout, Annemiek A. van der Eijk, Willem P. Brouwer, Florian van Bömmel, André Boonstra, Bettina E. Hansen, Thomas Berg, Harry L.A. Janssen, Robert A. de Man, Milan J. Sonneveld
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 56, Iss 1, Pp 31-39 (2023)
Background/Purpose(s): Since ALT flares after therapy withdrawal are associated with adverse outcomes, risk stratification is of major importance. We aimed to study whether off-treatment flares are related with virological outcomes, and if serum leve
Externí odkaz:
https://doaj.org/article/f650211b839742969e63754dc2c70f24
Autor:
Monique T.A. de Beijer, Karel Bezstarosti, Robbie Luijten, Wouter A.S. Doff, Patrick P.C. Boor, Roel F.A. Pieterman, Rachid Bouzid, Paula J. Biesta, Jan N.M. Ijzermans, Michail Doukas, Robert A. de Man, Andrea M. Woltman, Jeroen A.A. Demmers, Sonja I. Buschow
Publikováno v:
JHEP Reports, Vol 4, Iss 11, Pp 100576- (2022)
Background & Aims: Antigen-specific immunotherapy is a promising strategy to treat HBV infection and hepatocellular carcinoma (HCC). To facilitate killing of malignant and/or infected hepatocytes, it is vital to know which T cell targets are presente
Externí odkaz:
https://doaj.org/article/0c287e8b13e0403da76d048046b18aa2
Autor:
Yunlong Li, Changbo Qu, Bart Spee, Ruyi Zhang, Louis C. Penning, Robert A. de Man, Maikel P. Peppelenbosch, Hille Fieten, Qiuwei Pan
Publikováno v:
Irish Veterinary Journal, Vol 73, Iss 1, Pp 1-5 (2020)
Abstract Hepatitis E virus (HEV) as an emerging zoonotic pathogen causes a major public health issue. Transmission from domestic, wildlife and zoo animals to human has been widely reported. Whether pets also serve as reservoirs remains an intriguing
Externí odkaz:
https://doaj.org/article/e5fda4415dfe41d5bd13d11750f5b386
Autor:
Laurens A. van Kleef, Hannah S.J. Choi, Willem P. Brouwer, Bettina E. Hansen, Keyur Patel, Robert A. de Man, Harry L.A. Janssen, Robert J. de Knegt, Milan J. Sonneveld
Publikováno v:
JHEP Reports, Vol 3, Iss 5, Pp 100350- (2021)
Background & Aims: A recent consensus document has defined metabolic dysfunction-associated fatty liver disease (MAFLD) as hepatic steatosis together with overweight, diabetes, and/or a combination of other metabolic risk factors. The clinical releva
Externí odkaz:
https://doaj.org/article/608f7207c79146e982662214621c9049
Autor:
Warshan K. Katwaroe, Sylvia M. Brakenhoff, Daniël P. C. van der Spek, Robert J. de Knegt, Laurens A. van Kleef, Robert A. de Man, Adriaan J. P. van der Meer, Milan J. Sonneveld, the ICARUS Study Group
Publikováno v:
Viruses, Vol 14, Iss 10, p 2229 (2022)
Background and aims: Adherence to guidelines is associated with improved long-term outcomes in patients with chronic hepatitis B (CHB). We aimed to study the degree of adherence and determinants of non-adherence to management guidelines in a low ende
Externí odkaz:
https://doaj.org/article/cf14816242f74d6d8e6415a905a78352
Publikováno v:
International Journal of Infectious Diseases, Vol 87, Iss , Pp 39-42 (2019)
Objective: We report the immune response during a case of acute HEV response in a patient with an acute hepatitis E virus (HEV) genotype 3 infection in the Netherlands. Methods: Cytokine evaluation was performed via multiplex cytokine array for 65 im
Externí odkaz:
https://doaj.org/article/9f27391b107a452199ed3e760cca4272