Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert A. Swyka"'
Publikováno v:
Isr J Chem
Two catalytic systems for the formate-mediated cross-electrophile reductive coupling of 4-iodoansiole with 6-bromopyridines are described. Using homogenous rhodium or heterogeneous palladium catalysts, the product of reductive biaryl cross-coupling c
Autor:
Robert A. Swyka, David B. Berkowitz
Publikováno v:
Current Protocols in Chemical Biology. 9:285-305
The importance of discovering new chemical transformations and/or optimizing catalytic combinations has led to a flurry of activity in reaction screening. The in situ enzymatic screening (ISES) approach described here utilizes biological tools (enzym
Autor:
Guillaume Malik, David B. Berkowitz, Gregory A. Applegate, Virendra Kumar Tiwari, Xiang Fei, Robert A. Swyka
Publikováno v:
Chemical Science. 8:8050-8060
Herein we describe a formal thiocyanopalladation/carbocyclization transformation and its parametrization and optimization using a new elevated temperature plate-based version of our visual colorimetric enzymatic screening method for reaction discover
Autor:
Robert A. Swyka, William G. Shuler, Michael J. Krische, Tabitha T. Schempp, Brian J. Spinello
Publikováno v:
Chemistry
Direct conversion of aldehydes to ketones is achieved via rhodium-catalyzed vinyl triflate-aldehyde reductive coupling-redox isomerization mediated by potassium formate. This method circumvents premetalated C-nucleophiles and discrete redox manipulat
Autor:
Michael J. Krische, Robert A. Swyka, Wandi Zhang, Chunling Lan, William G. Shuler, Brian J. Spinello
Publikováno v:
J Am Chem Soc
A regiodivergent catalytic method for direct conversion of aldehydes to branched or linear alkyl ketones is described. Rhodium complexes modified by P(t)Bu(2)Me, catalyze formate-mediated aldehyde-vinyl bromide reductive coupling-redox isomerization
Publikováno v:
Journal of the American Chemical Society. 141(5)
The first intermolecular carbonyl arylations via transfer hydrogenative reductive coupling are described. Using rhodium catalysts modified by (t)Bu(2)PMe, sodium formate-mediated reductive coupling of aryl iodides with aldehydes occurs in a chemosele
Autor:
Sangeeta Dey, Sandip K. Roy, Weijun Shen, Xiang Fei, Kannan R. Karukurichi, Robert A. Swyka, David B. Berkowitz, Sylvain Broussy
Publikováno v:
Science Advances
Enzymes lead to the discovery of new, shape-tunable ligands for controlling catalytic chemistry.
This study introduces new methods of screening for and tuning chiral space and in so doing identifies a promising set of chiral ligands for asymmetr
This study introduces new methods of screening for and tuning chiral space and in so doing identifies a promising set of chiral ligands for asymmetr