Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Robert A. Mosey"'
Autor:
Daljinder K. Woloch, Jetze J. Tepe, Jason S. Fisk, Michael R. Kuszpit, Lauren M. Azevedo, Dillon P. Cogan, Jacob R. Ludwig, Theresa A. Lansdell, Gregory P. Patten, Robert A. Mosey
Publikováno v:
Journal of Medicinal Chemistry. 56:5974-5978
The proteasome has emerged as the primary target for the treatment of multiple myeloma. Unfortunately, nearly all patients develop resistance to competitive-type proteasome inhibitors, such as bortezomib. Herein, we describe the optimization of non-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2164432caa60c11da3c0eb317bb4a20c
https://doi.org/10.1021/jm400235r
https://doi.org/10.1021/jm400235r
Publikováno v:
Tetrahedron: Asymmetry. 19:2755-2762
Quaternary α-amino acids play vital roles in protein and synthetic chemistries. Stereoselective access to such molecules has been an intensive focus of research in recent years, and new methods are continuously being explored. The present mini-revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38775c13a348f321ef1b46733290564d
https://doi.org/10.1016/j.tetasy.2008.11.033
https://doi.org/10.1016/j.tetasy.2008.11.033
Autor:
Jetze J. Tepe, Robert A. Mosey
Publikováno v:
Tetrahedron Letters. 50:295-297
We report herein a racemic key intermediate in the synthesis of salinosporamide A via a tert -alkyl amino hydroxy carboxylic ester produced in an ene-type reaction of an oxazolone with an enol ether.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e5f2d4d370d9d9fb266995ef2b522b
https://doi.org/10.1016/j.tetlet.2008.10.154
https://doi.org/10.1016/j.tetlet.2008.10.154
Publikováno v:
ChemInform. 40
Quaternary α-amino acids play vital roles in protein and synthetic chemistries. Stereoselective access to such molecules has been an intensive focus of research in recent years, and new methods are continuously being explored. The present mini-revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8b58634f217b4ec3ea0d98aabe83f5
https://doi.org/10.1002/chin.200922229
https://doi.org/10.1002/chin.200922229
Autor:
Jetze J. Tepe, Robert A. Mosey
Publikováno v:
ChemInform. 40
We report herein a racemic key intermediate in the synthesis of salinosporamide A via a tert -alkyl amino hydroxy carboxylic ester produced in an ene-type reaction of an oxazolone with an enol ether.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f8359a9224f1c1fd3d7bc8750ed2c4
https://doi.org/10.1002/chin.200917204
https://doi.org/10.1002/chin.200917204
Publikováno v:
ChemInform. 39
tert-Alkyl amino hydroxy carboxylic acids are abundantly present within the structure of many biologically active natural products. We describe herein the synthesis of these substrates using an oxazolone-mediated ene-type reaction with enol ethers fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b579804b31f90f51338689e0890bfbae
https://doi.org/10.1002/chin.200831064
https://doi.org/10.1002/chin.200831064
Publikováno v:
Organic letters. 10(5)
tert-Alkyl amino hydroxy carboxylic acids are abundantly present within the structure of many biologically active natural products. We describe herein the synthesis of these substrates using an oxazolone-mediated ene-type reaction with enol ethers fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8420c1a83157dfd9a4eba3e94b36130d
https://pubmed.ncbi.nlm.nih.gov/18232699
https://pubmed.ncbi.nlm.nih.gov/18232699
Publikováno v:
Chemical Society reviews. 36(9)
The assembly of structurally diverse scaffolds via substrate controlled diversity oriented synthesis (DOS) has proven to be an effective tool in the discovery of novel biologically important compounds. This tutorial review aims to summarize some of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf7ed3adf20c3e7c00eb73b435401f4
https://pubmed.ncbi.nlm.nih.gov/17660876
https://pubmed.ncbi.nlm.nih.gov/17660876
Publikováno v:
Organic Letters; Mar2008, Vol. 10 Issue 5, p825-828, 4p