Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert A. Meigs"'
Publikováno v:
Endocrine research. 20(3)
Absolute values of cytochrome P-450 (cyt. P-450) content were determined by dual beam spectrophotometry in mitochondrial and microsomal fractions of granulosa cells and stroma (theca and interstitial cells) obtained from ovaries of immature rats trea
Autor:
Robert A. Meigs
Publikováno v:
Life sciences. 46(5)
All oxidative functions of aromatase, i.e., estrogen production, 19-oxygenated androgen production and 7-ethoxycoumarin deethylation, were inhibited in parallel in placental microsomes from non-smokers by the mechanism-based, time-dependent inactivat
Autor:
Robert A. Meigs, Arturo A. Olivera
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 376:426-435
Human term placental mitochondria were resolved by differential centrifugation into three fractions, heavy mitochondria, light mitochondria and a third, less dense fraction. Approximately equal amounts of mitochondrial protein were found in the three
Autor:
Robert A. Meigs
Publikováno v:
Biochemical and Biophysical Research Communications. 145:1012-1018
The constitutive 7-ethoxycoumarin deethylase activity of human placental microsomes from non-smokers was acutely inhibited by a number of androgens which serve as substrates for and/or competitive inhibitors of estrogen synthesis by the aromatase act
Autor:
Krishna B. Moorthy, Robert A. Meigs
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 528:222-229
Structural and functional aspects of the association of aromatizing activity with placental mitochondrial preparations were examined. Total mitochondrial preparations, previously characterized with respect to their capacity for oxidative phosphorylat
Autor:
Robert A. Meigs, Kenneth J. Ryan
Publikováno v:
Journal of Biological Chemistry. 246:83-87
Intermediate steps in the aromatization of 4-androstene-3,17-dione to estrone, catalyzed by human placental microsomes, have been evaluated through the use of normal and hypothetical intermediate compounds as substrates and the oxidases involved have
Autor:
Clarence F. Pautzke, Robert C. Meigs
Publikováno v:
Transactions of the American Fisheries Society. 70:209-220
Steelhead trout are taken in great numbers as immature fish by stream anglers during the regular trout season. They also are caught during the winter months as they ascend the rivers to spawn. Posters were put up along the rivers describing the taggi
Autor:
Kenneth J. Ryan, Robert A. Meigs
Publikováno v:
Journal of Biological Chemistry. 241:4011-4015
16α-Hydroxysteroid dehydrogenase, an estrogen-induced, soluble enzyme from rat kidneys, has been concentrated, partially purified, and separated from 16β- and 17β-hydroxysteroid dehydrogenase activities by a carboxymethyl cellulose column fraction
Autor:
Robert A. Meigs, Lewis L. Engel
Publikováno v:
Endocrinology. 69:152-162
Adrenocortical steroids were incubated with preparations of human liver and term placenta and the metabolic products were isolated and characterized. Human liver homogenates interconverted cortisol and cortisone and reduced the latter substance to 5
Autor:
C. Albert Kind, Robert A. Meigs
Publikováno v:
The Journal of Organic Chemistry. 20:1116-1118